ENSG00000148400

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000651671 ENSG00000148400 No_inf pgKDN_inf NOTCH1 protein_coding protein_coding 82.79545 34.26134 97.10361 0.921201 1.04231 1.502671 10.395103 1.637021 15.981970 1.6370206 5.4865005 3.27941718 0.1088750 0.047800 0.163275 0.115475 0.457515434 0.009310135 FALSE TRUE
ENST00000679969 ENSG00000148400 No_inf pgKDN_inf NOTCH1 protein_coding retained_intron 82.79545 34.26134 97.10361 0.921201 1.04231 1.502671 3.034361 3.128274 1.345433 0.5190961 0.3057949 -1.21121741 0.0486750 0.092575 0.013950 -0.078625 0.009310135 0.009310135 FALSE TRUE
ENST00000680003 ENSG00000148400 No_inf pgKDN_inf NOTCH1 protein_coding retained_intron 82.79545 34.26134 97.10361 0.921201 1.04231 1.502671 10.163293 7.457103 7.674898 0.8735186 1.2797562 0.04147766 0.1420750 0.216275 0.078725 -0.137550 0.032271108 0.009310135 FALSE TRUE
ENST00000680218 ENSG00000148400 No_inf pgKDN_inf NOTCH1 protein_coding protein_coding 82.79545 34.26134 97.10361 0.921201 1.04231 1.502671 10.655716 4.530165 9.482918 1.6008264 5.2515671 1.06410702 0.1288917 0.133525 0.099200 -0.034325 0.882275402 0.009310135 FALSE TRUE
ENST00000680778 ENSG00000148400 No_inf pgKDN_inf NOTCH1 protein_coding protein_coding 82.79545 34.26134 97.10361 0.921201 1.04231 1.502671 44.345155 15.359171 56.792541 0.3039379 0.3770221 1.88591608 0.5181333 0.448825 0.585175 0.136350 0.050295376 0.009310135 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000148400 E001 0.1268540 1.236872e-02 1.732356e-01   9 136494433 136494443 11 - 0.000 0.147 11.094
ENSG00000148400 E002 4.6969342 7.743132e-03 8.556567e-01 9.491770e-01 9 136494444 136494456 13 - 0.712 0.736 0.095
ENSG00000148400 E003 750.2236363 3.863486e-05 2.090480e-05 6.395231e-04 9 136494457 136495735 1279 - 2.817 2.863 0.150
ENSG00000148400 E004 817.8263749 4.383197e-05 3.008079e-02 1.631958e-01 9 136495736 136497558 1823 - 2.862 2.884 0.073
ENSG00000148400 E005 54.6158650 3.015202e-03 3.815599e-01 6.679775e-01 9 136498899 136498996 98 - 1.688 1.731 0.146
ENSG00000148400 E006 0.1170040 1.179379e-02 1.000000e+00   9 136498997 136499111 115 - 0.060 0.000 -12.469
ENSG00000148400 E007 52.1584691 2.727866e-04 6.979145e-01 8.767048e-01 9 136499112 136499259 148 - 1.676 1.694 0.060
ENSG00000148400 E008 12.1998124 1.276475e-02 5.523065e-09 4.103044e-07 9 136499260 136500551 1292 - 0.850 1.388 1.943
ENSG00000148400 E009 96.5967161 5.800768e-04 7.329706e-01 8.938145e-01 9 136500552 136500847 296 - 1.941 1.953 0.040
ENSG00000148400 E010 56.4951203 3.684966e-04 7.630610e-01 9.075758e-01 9 136501748 136501913 166 - 1.712 1.725 0.045
ENSG00000148400 E011 31.6549913 4.437297e-04 8.717392e-02 3.059696e-01 9 136502001 136502088 88 - 1.440 1.538 0.334
ENSG00000148400 E012 42.5387851 3.222231e-03 5.741470e-01 8.092524e-01 9 136502272 136502436 165 - 1.586 1.617 0.104
ENSG00000148400 E013 19.9891362 6.741369e-04 9.485214e-01 9.866788e-01 9 136502437 136502488 52 - 1.278 1.282 0.016
ENSG00000148400 E014 5.0508678 2.938310e-03 2.697614e-05 7.937431e-04 9 136502489 136502775 287 - 0.547 1.029 1.941
ENSG00000148400 E015 7.4331892 2.782931e-03 1.415676e-09 1.174663e-07 9 136502776 136503181 406 - 0.615 1.224 2.336
ENSG00000148400 E016 39.9218225 3.624724e-04 5.145176e-01 7.710858e-01 9 136503182 136503330 149 - 1.578 1.543 -0.119
ENSG00000148400 E017 99.4506854 1.909142e-04 2.415714e-03 2.935762e-02 9 136504673 136505104 432 - 1.985 1.879 -0.356
ENSG00000148400 E018 111.4526316 1.427697e-04 1.954888e-01 4.758820e-01 9 136505310 136505881 572 - 2.018 1.976 -0.140
ENSG00000148400 E019 28.6943562 1.716842e-03 1.845066e-01 4.616859e-01 9 136506527 136506639 113 - 1.452 1.365 -0.299
ENSG00000148400 E020 28.1593568 5.379802e-04 1.476181e-02 1.038835e-01 9 136506716 136506835 120 - 1.461 1.300 -0.557
ENSG00000148400 E021 28.2012528 1.749455e-02 1.926437e-01 4.724961e-01 9 136506836 136506973 138 - 1.450 1.342 -0.373
ENSG00000148400 E022 32.8314340 5.318730e-03 5.964319e-01 8.226171e-01 9 136507305 136507437 133 - 1.495 1.460 -0.121
ENSG00000148400 E023 32.9350197 8.559162e-03 5.097723e-01 7.675183e-01 9 136507955 136508139 185 - 1.474 1.517 0.147
ENSG00000148400 E024 14.8116909 6.853778e-03 8.461178e-01 9.453847e-01 9 136508232 136508292 61 - 1.162 1.143 -0.065
ENSG00000148400 E025 14.0436519 6.389084e-03 2.791787e-01 5.724528e-01 9 136508293 136508385 93 - 1.162 1.060 -0.364
ENSG00000148400 E026 27.0884670 8.944111e-03 1.258299e-01 3.761121e-01 9 136508870 136509071 202 - 1.436 1.318 -0.410
ENSG00000148400 E027 0.0000000       9 136509072 136509343 272 -      
ENSG00000148400 E028 33.5044361 4.366585e-04 7.023819e-04 1.138631e-02 9 136509733 136509961 229 - 1.544 1.334 -0.724
ENSG00000148400 E029 0.3811266 2.729553e-02 1.184559e-02   9 136510510 136510652 143 - 0.000 0.345 14.775
ENSG00000148400 E030 32.0246765 9.285391e-03 8.463845e-02 3.005909e-01 9 136510653 136510800 148 - 1.508 1.380 -0.438
ENSG00000148400 E031 11.5276154 1.745172e-03 5.187791e-01 7.736501e-01 9 136510801 136510805 5 - 1.073 1.012 -0.223
ENSG00000148400 E032 28.5407245 4.779024e-04 7.490641e-02 2.792178e-01 9 136511152 136511271 120 - 1.457 1.342 -0.396
ENSG00000148400 E033 0.2444846 1.654860e-02 4.332212e-01   9 136512693 136512773 81 - 0.060 0.147 1.443
ENSG00000148400 E034 0.0000000       9 136512774 136512848 75 -      
ENSG00000148400 E035 24.6990894 1.823294e-02 2.239272e-01 5.115328e-01 9 136513021 136513134 114 - 1.396 1.282 -0.396
ENSG00000148400 E036 30.1108586 2.191069e-02 2.257935e-01 5.136641e-01 9 136513392 136513537 146 - 1.478 1.365 -0.390
ENSG00000148400 E037 0.0000000       9 136513538 136513551 14 -      
ENSG00000148400 E038 27.1167220 4.724228e-04 1.013410e-01 3.323842e-01 9 136514510 136514702 193 - 1.433 1.326 -0.373
ENSG00000148400 E039 20.4204243 8.245733e-04 2.432861e-01 5.332815e-01 9 136515290 136515400 111 - 1.311 1.224 -0.305
ENSG00000148400 E040 37.0183748 8.079113e-04 3.191527e-01 6.118984e-01 9 136515483 136515716 234 - 1.551 1.495 -0.192
ENSG00000148400 E041 17.5968120 4.306631e-03 6.329640e-01 8.428373e-01 9 136515981 136516094 114 - 1.216 1.254 0.135
ENSG00000148400 E042 13.8945374 3.894541e-03 8.906974e-02 3.096885e-01 9 136517272 136517385 114 - 1.170 1.012 -0.573
ENSG00000148400 E043 19.8872881 1.506440e-03 2.491163e-02 1.451245e-01 9 136517752 136517937 186 - 1.320 1.143 -0.623
ENSG00000148400 E044 17.6561701 7.670793e-04 3.007833e-01 5.937069e-01 9 136518137 136518292 156 - 1.250 1.168 -0.290
ENSG00000148400 E045 29.6232863 4.725950e-04 5.024685e-02 2.214898e-01 9 136518591 136518824 234 - 1.474 1.350 -0.429
ENSG00000148400 E046 14.1412564 9.876466e-03 2.712375e-01 5.649583e-01 9 136519443 136519565 123 - 1.166 1.060 -0.380
ENSG00000148400 E047 0.7428375 1.391074e-02 4.425670e-02 2.057530e-01 9 136522572 136522849 278 - 0.113 0.417 2.443
ENSG00000148400 E048 26.6766757 6.273922e-04 4.785191e-01 7.444887e-01 9 136522850 136523188 339 - 1.411 1.365 -0.159
ENSG00000148400 E049 22.9981170 6.217728e-04 1.448905e-02 1.026606e-01 9 136523717 136523924 208 - 1.380 1.202 -0.624
ENSG00000148400 E050 9.3169900 7.009823e-03 2.063949e-02 1.294384e-01 9 136523925 136523979 55 - 1.033 0.767 -1.017
ENSG00000148400 E051 8.6925774 1.965800e-03 8.989659e-04 1.381334e-02 9 136544024 136544102 79 - 1.027 0.626 -1.579
ENSG00000148400 E052 11.0905399 1.225641e-03 2.916163e-03 3.380826e-02 9 136545726 136546048 323 - 1.110 0.796 -1.178

Help

Please Click HERE to learn more details about the results from DEXseq.