ENSG00000149091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000527211 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding retained_intron 165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 8.511336 11.98619 5.387880 0.5604728 0.06611829 -1.1521111 0.05017500 0.058800 0.042525 -0.016275 6.878598e-01 1.07132e-09 FALSE TRUE
ENST00000528173 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding retained_intron 165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 7.462017 14.21808 2.027176 0.8514945 0.31178153 -2.8040983 0.04095000 0.069950 0.016000 -0.053950 6.179867e-04 1.07132e-09 TRUE TRUE
ENST00000529660 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding protein_coding_CDS_not_defined 165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 14.512205 20.15947 9.601051 1.9654443 1.63987509 -1.0694068 0.08543333 0.099350 0.075750 -0.023600 7.925891e-01 1.07132e-09 FALSE FALSE
ENST00000529698 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding retained_intron 165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 9.251724 14.87806 6.532008 1.6448718 1.02125056 -1.1863502 0.05404167 0.072800 0.051550 -0.021250 6.964917e-01 1.07132e-09 FALSE TRUE
ENST00000534802 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding retained_intron 165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 3.414674 10.24402 0.000000 1.9809451 0.00000000 -10.0019741 0.01679167 0.050375 0.000000 -0.050375 1.071320e-09 1.07132e-09 FALSE TRUE
MSTRG.4692.5 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding   165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 77.454152 77.29247 69.636977 3.6616250 2.70913288 -0.1504537 0.48256667 0.379400 0.549875 0.170475 2.138353e-03 1.07132e-09 FALSE TRUE
MSTRG.4692.6 ENSG00000149091 No_inf pgKDN_inf DGKZ protein_coding   165.5605 203.7105 126.6538 2.517318 1.013057 -0.6855867 15.024387 17.44629 16.785733 3.8608358 2.92461142 -0.0556523 0.09405833 0.085675 0.132425 0.046750 6.353312e-01 1.07132e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149091 E001 0.0000000       11 46332905 46333487 583 +      
ENSG00000149091 E002 0.6351783 0.0336957202 8.109591e-02 2.926028e-01 11 46338598 46338890 293 + 0.000 0.288 10.778
ENSG00000149091 E003 0.0000000       11 46345267 46345381 115 +      
ENSG00000149091 E004 0.1170040 0.0117271967 3.082481e-01   11 46345382 46345390 9 + 0.120 0.000 -13.046
ENSG00000149091 E005 0.2441403 0.0164887991 6.805353e-01   11 46345391 46345402 12 + 0.120 0.075 -0.764
ENSG00000149091 E006 0.2441403 0.0164887991 6.805353e-01   11 46345403 46345413 11 + 0.120 0.075 -0.764
ENSG00000149091 E007 0.8541100 0.0151580791 2.878268e-01 5.813014e-01 11 46345414 46345422 9 + 0.357 0.194 -1.179
ENSG00000149091 E008 4.4101516 0.0065792050 1.240489e-01 3.731431e-01 11 46345423 46345431 9 + 0.829 0.642 -0.764
ENSG00000149091 E009 4.5271556 0.0074364054 8.681186e-02 3.054392e-01 11 46345432 46345433 2 + 0.849 0.642 -0.842
ENSG00000149091 E010 4.9081873 0.0331326667 2.311830e-01 5.196991e-01 11 46345434 46345436 3 + 0.849 0.694 -0.619
ENSG00000149091 E011 77.2164918 0.0002148003 1.705141e-04 3.671261e-03 11 46345437 46345585 149 + 1.954 1.823 -0.441
ENSG00000149091 E012 4.3089092 0.0307653034 5.204068e-01 7.747280e-01 11 46345586 46345589 4 + 0.762 0.677 -0.349
ENSG00000149091 E013 0.3716522 0.2314423023 1.000000e+00   11 46347463 46347522 60 + 0.120 0.138 0.235
ENSG00000149091 E014 0.7346216 0.0144814775 5.232421e-01 7.766548e-01 11 46347523 46347587 65 + 0.292 0.194 -0.764
ENSG00000149091 E015 1.7152385 0.0109583881 3.329238e-01 6.249708e-01 11 46347588 46347820 233 + 0.510 0.365 -0.764
ENSG00000149091 E016 0.0000000       11 46361522 46361605 84 +      
ENSG00000149091 E017 0.0000000       11 46361606 46361606 1 +      
ENSG00000149091 E018 0.8534780 0.0159834260 2.883018e-01 5.818683e-01 11 46361607 46361706 100 + 0.357 0.194 -1.179
ENSG00000149091 E019 1.4783677 0.0091936591 7.461981e-01 8.996211e-01 11 46361707 46361963 257 + 0.414 0.365 -0.278
ENSG00000149091 E020 4.7799812 0.0030954818 1.435873e-01 4.035349e-01 11 46366015 46366243 229 + 0.849 0.677 -0.690
ENSG00000149091 E021 9.1476415 0.0279231960 7.675640e-03 6.721222e-02 11 46366244 46366526 283 + 1.158 0.857 -1.112
ENSG00000149091 E022 15.1632689 0.0008895621 3.209252e-01 6.139388e-01 11 46366527 46366984 458 + 1.237 1.162 -0.266
ENSG00000149091 E023 33.7111789 0.0004352405 1.713290e-02 1.144552e-01 11 46367291 46367314 24 + 1.598 1.473 -0.425
ENSG00000149091 E024 83.5718691 0.0001792100 2.371497e-02 1.408948e-01 11 46367315 46367399 85 + 1.956 1.879 -0.256
ENSG00000149091 E025 54.1269277 0.0002544493 1.351997e-01 3.908797e-01 11 46367652 46367654 3 + 1.762 1.699 -0.211
ENSG00000149091 E026 101.7771042 0.0001591923 8.457829e-03 7.181606e-02 11 46367655 46367747 93 + 2.043 1.963 -0.270
ENSG00000149091 E027 1.6036204 0.0086691525 9.183590e-01 9.743996e-01 11 46367748 46368001 254 + 0.414 0.398 -0.085
ENSG00000149091 E028 34.4623707 0.0010786569 5.351803e-02 2.303441e-01 11 46368002 46368004 3 + 1.594 1.492 -0.349
ENSG00000149091 E029 76.1344888 0.0087953073 2.396368e-02 1.417790e-01 11 46368005 46368079 75 + 1.940 1.823 -0.393
ENSG00000149091 E030 9.5471368 0.0154806514 2.377399e-04 4.820399e-03 11 46368080 46368177 98 + 0.684 1.115 1.651
ENSG00000149091 E031 75.6941029 0.0008765336 2.802445e-22 9.566271e-20 11 46368178 46369363 1186 + 1.557 1.972 1.403
ENSG00000149091 E032 15.5510905 0.0009272274 1.072432e-06 4.952103e-05 11 46369364 46369493 130 + 0.886 1.309 1.531
ENSG00000149091 E033 77.4269856 0.0042013786 3.373073e-02 1.747750e-01 11 46369494 46369550 57 + 1.934 1.840 -0.315
ENSG00000149091 E034 14.7736683 0.0085656435 1.673426e-12 2.103836e-10 11 46369551 46369940 390 + 0.550 1.332 3.005
ENSG00000149091 E035 58.6194550 0.0002485235 5.291472e-04 9.123730e-03 11 46369941 46370009 69 + 1.840 1.702 -0.466
ENSG00000149091 E036 49.1696436 0.0002923884 8.016001e-02 2.906258e-01 11 46371313 46371384 72 + 1.729 1.653 -0.260
ENSG00000149091 E037 83.8906557 0.0023314997 2.451998e-01 5.356574e-01 11 46371487 46371603 117 + 1.938 1.893 -0.152
ENSG00000149091 E038 47.3683032 0.0007027375 2.305553e-01 5.190056e-01 11 46371704 46371724 21 + 1.700 1.645 -0.185
ENSG00000149091 E039 63.1571018 0.0002314263 8.122414e-01 9.309356e-01 11 46371725 46371775 51 + 1.794 1.785 -0.031
ENSG00000149091 E040 79.1216907 0.0002006137 2.107222e-01 4.953620e-01 11 46372075 46372170 96 + 1.912 1.869 -0.147
ENSG00000149091 E041 70.8986108 0.0072677978 1.579412e-01 4.247372e-01 11 46372428 46372510 83 + 1.882 1.811 -0.241
ENSG00000149091 E042 1.6499766 0.0101236199 1.301089e-03 1.835066e-02 11 46372511 46372616 106 + 0.000 0.537 14.846
ENSG00000149091 E043 63.5237684 0.0025965064 1.703936e-01 4.426099e-01 11 46372617 46372677 61 + 1.828 1.768 -0.202
ENSG00000149091 E044 1.2618281 0.0105174562 5.432815e-02 2.321221e-01 11 46372678 46372770 93 + 0.120 0.430 2.406
ENSG00000149091 E045 47.1181936 0.0004283044 1.963047e-01 4.769572e-01 11 46372771 46372843 73 + 1.700 1.642 -0.198
ENSG00000149091 E046 32.8346373 0.0006012957 5.820406e-01 8.138723e-01 11 46372844 46372884 41 + 1.530 1.500 -0.101
ENSG00000149091 E047 1.3521493 0.0151731788 5.764252e-01 8.104891e-01 11 46372885 46372897 13 + 0.414 0.328 -0.501
ENSG00000149091 E048 32.9794301 0.0004835326 7.984780e-01 9.242035e-01 11 46372961 46373101 141 + 1.521 1.508 -0.047
ENSG00000149091 E049 45.0035748 0.0088004027 9.905885e-01 1.000000e+00 11 46374157 46374235 79 + 1.644 1.644 -0.001
ENSG00000149091 E050 74.3606484 0.0029205268 5.679259e-01 8.055837e-01 11 46374399 46374428 30 + 1.873 1.849 -0.080
ENSG00000149091 E051 68.9070195 0.0075982637 5.071115e-01 7.656500e-01 11 46374429 46374454 26 + 1.846 1.813 -0.112
ENSG00000149091 E052 93.9062489 0.0001899921 1.373925e-01 3.945478e-01 11 46374604 46374666 63 + 1.988 1.941 -0.160
ENSG00000149091 E053 0.5070689 0.2069802181 1.931774e-01 4.729811e-01 11 46374667 46374765 99 + 0.000 0.243 12.226
ENSG00000149091 E054 102.9349317 0.0001566356 2.069242e-02 1.295702e-01 11 46374766 46374839 74 + 2.042 1.971 -0.236
ENSG00000149091 E055 109.3638420 0.0007477097 1.983421e-01 4.797678e-01 11 46374934 46375023 90 + 2.049 2.009 -0.135
ENSG00000149091 E056 58.0657239 0.0004478262 6.990264e-02 2.674609e-01 11 46375024 46375045 22 + 1.798 1.725 -0.250
ENSG00000149091 E057 148.6135043 0.0011792895 5.914513e-01 8.193392e-01 11 46375432 46375631 200 + 2.166 2.150 -0.052
ENSG00000149091 E058 114.7444337 0.0002670559 1.195046e-01 3.654039e-01 11 46375851 46375951 101 + 2.073 2.028 -0.153
ENSG00000149091 E059 99.9402091 0.0012690076 6.325718e-01 8.426179e-01 11 46376066 46376145 80 + 1.995 1.979 -0.054
ENSG00000149091 E060 108.2911148 0.0027539310 3.812046e-01 6.676372e-01 11 46376328 46376397 70 + 1.998 2.031 0.109
ENSG00000149091 E061 0.0000000       11 46376520 46376523 4 +      
ENSG00000149091 E062 81.2046466 0.0026059566 2.973809e-01 5.905157e-01 11 46376524 46376564 41 + 1.922 1.881 -0.140
ENSG00000149091 E063 4.9810687 0.0058051080 2.118243e-01 4.968269e-01 11 46376565 46377072 508 + 0.654 0.809 0.635
ENSG00000149091 E064 49.0378700 0.0012207470 8.560600e-02 3.028002e-01 11 46377073 46377147 75 + 1.729 1.651 -0.266
ENSG00000149091 E065 30.9060809 0.0005023600 8.618384e-01 9.521763e-01 11 46377148 46377212 65 + 1.491 1.482 -0.033
ENSG00000149091 E066 88.6641557 0.0015201410 2.882869e-05 8.378128e-04 11 46377213 46377967 755 + 1.824 1.983 0.536
ENSG00000149091 E067 7.4924292 0.0125224310 3.465726e-02 1.779166e-01 11 46377968 46377969 2 + 0.738 0.984 0.952
ENSG00000149091 E068 23.5071129 0.0005933797 1.465565e-02 1.034112e-01 11 46377970 46378197 228 + 1.261 1.421 0.558
ENSG00000149091 E069 49.8217900 0.0057135597 8.824117e-01 9.604482e-01 11 46378198 46378229 32 + 1.692 1.684 -0.025
ENSG00000149091 E070 10.6568415 0.0101104319 1.142523e-04 2.650358e-03 11 46378230 46378456 227 + 0.738 1.156 1.579
ENSG00000149091 E071 94.6949790 0.0006620830 4.925964e-02 2.187722e-01 11 46378457 46378500 44 + 1.917 1.984 0.225
ENSG00000149091 E072 77.7573515 0.0002123553 5.223694e-28 2.657875e-25 11 46378501 46378893 393 + 1.538 1.990 1.531
ENSG00000149091 E073 33.0500991 0.0006123133 5.849283e-10 5.214466e-08 11 46378894 46378990 97 + 1.237 1.613 1.299
ENSG00000149091 E074 151.7033727 0.0022683604 1.120320e-01 3.516869e-01 11 46378991 46379111 121 + 2.131 2.182 0.170
ENSG00000149091 E075 94.9166336 0.0070506199 4.287995e-01 7.072053e-01 11 46379203 46379236 34 + 1.987 1.949 -0.127
ENSG00000149091 E076 43.7613518 0.0028857664 3.006448e-08 1.948915e-06 11 46379237 46379453 217 + 1.408 1.718 1.062
ENSG00000149091 E077 12.9149867 0.0015011372 1.731387e-05 5.453900e-04 11 46379454 46379468 15 + 0.829 1.230 1.476
ENSG00000149091 E078 158.1221859 0.0002623915 4.347199e-01 7.118575e-01 11 46379469 46379568 100 + 2.169 2.189 0.067
ENSG00000149091 E079 356.5018904 0.0007468519 7.985873e-01 9.242309e-01 11 46379831 46380554 724 + 2.531 2.536 0.016

Help

Please Click HERE to learn more details about the results from DEXseq.