ENSG00000149177

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000418331 ENSG00000149177 No_inf pgKDN_inf PTPRJ protein_coding protein_coding 89.79875 51.65092 114.0268 1.642615 0.6231978 1.142354 35.311362 13.352070 51.409587 2.4088588 1.105494 1.9441745 0.3694583 0.260125 0.450775 0.190650 0.09400964 0.04060492 FALSE  
MSTRG.4739.3 ENSG00000149177 No_inf pgKDN_inf PTPRJ protein_coding   89.79875 51.65092 114.0268 1.642615 0.6231978 1.142354 1.749209 3.378979 0.000000 2.6302168 0.000000 -8.4047069 0.0271500 0.063750 0.000000 -0.063750 0.35418743 0.04060492 FALSE  
MSTRG.4739.5 ENSG00000149177 No_inf pgKDN_inf PTPRJ protein_coding   89.79875 51.65092 114.0268 1.642615 0.6231978 1.142354 3.616683 4.378295 2.766845 0.7505690 0.244570 -0.6602138 0.0479500 0.083925 0.024250 -0.059675 0.04060492 0.04060492 FALSE  
MSTRG.4739.9 ENSG00000149177 No_inf pgKDN_inf PTPRJ protein_coding   89.79875 51.65092 114.0268 1.642615 0.6231978 1.142354 46.147625 28.683581 57.059692 0.4044832 1.276340 0.9919967 0.5217500 0.556575 0.500525 -0.056050 0.67319414 0.04060492 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149177 E001 0.1176306 0.0117887963 1.000000e+00   11 47980425 47980558 134 + 0.064 0.000 -8.258
ENSG00000149177 E002 0.1176306 0.0117887963 1.000000e+00   11 47980559 47980576 18 + 0.064 0.000 -10.311
ENSG00000149177 E003 0.2448930 0.0164964802 5.323248e-01   11 47980577 47980579 3 + 0.064 0.139 1.241
ENSG00000149177 E004 2.8776115 0.0050521203 2.694758e-01 5.631334e-01 11 47980580 47980722 143 + 0.605 0.460 -0.685
ENSG00000149177 E005 0.6001197 0.0150594455 6.080670e-01 8.292158e-01 11 47980723 47980726 4 + 0.214 0.139 -0.759
ENSG00000149177 E006 23.7041943 0.0079305232 9.518835e-02 3.211727e-01 11 47980727 47981008 282 + 1.390 1.289 -0.354
ENSG00000149177 E007 0.4978483 0.0314343119 7.643210e-02   11 48044804 48044871 68 + 0.064 0.328 2.826
ENSG00000149177 E008 0.3629695 0.0166533808 9.411011e-01   11 48046230 48046331 102 + 0.120 0.139 0.241
ENSG00000149177 E009 10.1487926 0.0244234945 3.683506e-07 1.879529e-05 11 48069121 48069812 692 + 0.749 1.321 2.111
ENSG00000149177 E010 9.4569600 0.0014401376 1.670238e-02 1.126881e-01 11 48110058 48110076 19 + 1.049 0.822 -0.852
ENSG00000149177 E011 12.6135506 0.0011100215 1.059559e-01 3.408385e-01 11 48112747 48112791 45 + 1.138 1.017 -0.437
ENSG00000149177 E012 38.6468943 0.0003574186 1.002941e-01 3.307841e-01 11 48112792 48112983 192 + 1.584 1.523 -0.209
ENSG00000149177 E013 54.8454701 0.0003021811 1.841632e-01 4.612700e-01 11 48121003 48121266 264 + 1.725 1.692 -0.112
ENSG00000149177 E014 48.1404508 0.0002841887 2.862182e-02 1.584727e-01 11 48123613 48123870 258 + 1.682 1.604 -0.268
ENSG00000149177 E015 48.4085539 0.0003450102 8.898884e-01 9.632796e-01 11 48124968 48125186 219 + 1.656 1.675 0.065
ENSG00000149177 E016 67.0236767 0.0002259356 9.977530e-01 1.000000e+00 11 48127780 48128043 264 + 1.792 1.818 0.086
ENSG00000149177 E017 71.1126664 0.0004148731 2.196257e-01 5.062430e-01 11 48130459 48130716 258 + 1.833 1.810 -0.076
ENSG00000149177 E018 6.5507008 0.0305427310 2.768306e-01 5.702484e-01 11 48131511 48132720 1210 + 0.796 0.949 0.589
ENSG00000149177 E019 0.4894765 0.0158810334 4.303177e-01   11 48136017 48136038 22 + 0.120 0.244 1.241
ENSG00000149177 E020 55.5740013 0.0046286654 1.329804e-03 1.866293e-02 11 48136039 48136296 258 + 1.761 1.616 -0.493
ENSG00000149177 E021 71.0375663 0.0002168176 3.140787e-02 1.672265e-01 11 48137003 48137281 279 + 1.843 1.784 -0.198
ENSG00000149177 E022 93.6950570 0.0005647737 4.711672e-04 8.332080e-03 11 48139486 48139776 291 + 1.972 1.874 -0.332
ENSG00000149177 E023 52.7181928 0.0010066635 2.725679e-02 1.535158e-01 11 48142919 48143050 132 + 1.721 1.642 -0.266
ENSG00000149177 E024 76.2131406 0.0002689396 5.618438e-04 9.564116e-03 11 48144675 48144885 211 + 1.886 1.779 -0.362
ENSG00000149177 E025 31.7156106 0.0004278995 1.072598e-02 8.412023e-02 11 48145000 48145077 78 + 1.519 1.393 -0.433
ENSG00000149177 E026 21.7447873 0.0006318332 3.216473e-02 1.697002e-01 11 48145078 48145124 47 + 1.361 1.235 -0.441
ENSG00000149177 E027 37.0450268 0.0003719050 6.975014e-01 8.765533e-01 11 48146876 48146963 88 + 1.547 1.552 0.016
ENSG00000149177 E028 30.1946026 0.0004625190 8.374389e-01 9.417713e-01 11 48149447 48149488 42 + 1.451 1.488 0.127
ENSG00000149177 E029 1.9527388 0.0214487385 3.034923e-01 5.968480e-01 11 48149489 48149866 378 + 0.386 0.560 0.878
ENSG00000149177 E030 21.5853709 0.0009519133 5.769448e-01 8.108544e-01 11 48149990 48149998 9 + 1.327 1.313 -0.047
ENSG00000149177 E031 47.3165635 0.0003177155 6.426257e-02 2.552523e-01 11 48150096 48150183 88 + 1.671 1.608 -0.215
ENSG00000149177 E032 57.5662962 0.0029042943 8.821992e-02 3.080081e-01 11 48153796 48153886 91 + 1.753 1.695 -0.195
ENSG00000149177 E033 60.6213993 0.0004727936 6.319449e-03 5.859260e-02 11 48155801 48155874 74 + 1.784 1.692 -0.314
ENSG00000149177 E034 82.2164737 0.0001861629 1.057645e-06 4.900602e-05 11 48155985 48156119 135 + 1.931 1.773 -0.533
ENSG00000149177 E035 75.6038909 0.0002328831 3.132743e-04 6.012860e-03 11 48159930 48160049 120 + 1.884 1.770 -0.384
ENSG00000149177 E036 84.5415881 0.0002085818 2.803668e-02 1.564380e-01 11 48163458 48163618 161 + 1.916 1.863 -0.179
ENSG00000149177 E037 70.5284093 0.0002435218 1.981479e-01 4.795347e-01 11 48164380 48164515 136 + 1.830 1.805 -0.083
ENSG00000149177 E038 1657.9908454 0.0006488515 4.287949e-21 1.263750e-18 11 48167204 48170839 3636 + 3.156 3.249 0.309

Help

Please Click HERE to learn more details about the results from DEXseq.