ENSG00000149428

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000614711 ENSG00000149428 No_inf pgKDN_inf HYOU1 protein_coding protein_coding 141.4636 86.85548 152.0442 1.455985 3.341166 0.8077312 54.21171 31.571891 58.52832 1.199836 8.1777635 0.8902838 0.3797917 0.36445 0.38225 0.01780 0.95492354 0.00950986 FALSE TRUE
ENST00000617285 ENSG00000149428 No_inf pgKDN_inf HYOU1 protein_coding protein_coding 141.4636 86.85548 152.0442 1.455985 3.341166 0.8077312 16.72337 3.621318 20.79968 1.115175 5.1748645 2.5186897 0.1064833 0.04190 0.13895 0.09705 0.18334924 0.00950986 FALSE TRUE
ENST00000652093 ENSG00000149428 No_inf pgKDN_inf HYOU1 protein_coding protein_coding 141.4636 86.85548 152.0442 1.455985 3.341166 0.8077312 15.50017 9.934862 21.04326 2.373187 0.9215984 1.0820205 0.1119000 0.11365 0.13865 0.02500 0.82818222 0.00950986 FALSE TRUE
ENST00000694928 ENSG00000149428 No_inf pgKDN_inf HYOU1 protein_coding protein_coding 141.4636 86.85548 152.0442 1.455985 3.341166 0.8077312 45.36000 36.566115 42.58280 1.561120 1.9128521 0.2197077 0.3357500 0.42095 0.27970 -0.14125 0.00950986 0.00950986 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149428 E001 0.0000000       11 119044188 119044191 4 -      
ENSG00000149428 E002 0.0000000       11 119044192 119044259 68 -      
ENSG00000149428 E003 0.0000000       11 119044260 119044310 51 -      
ENSG00000149428 E004 0.0000000       11 119044311 119044451 141 -      
ENSG00000149428 E005 129.8149023 1.293219e-04 2.071967e-04 0.0043117315 11 119044452 119044907 456 - 2.060 2.161 0.338
ENSG00000149428 E006 244.7495813 6.274314e-04 1.339776e-05 0.0004395344 11 119044908 119045126 219 - 2.337 2.431 0.313
ENSG00000149428 E007 215.6517415 9.489646e-05 1.942100e-01 0.4739817741 11 119045127 119045310 184 - 2.308 2.336 0.095
ENSG00000149428 E008 86.7157570 5.492155e-03 4.005940e-01 0.6839550548 11 119045311 119045588 278 - 1.911 1.950 0.131
ENSG00000149428 E009 72.4527774 7.310546e-03 6.922155e-01 0.8740235066 11 119045589 119045654 66 - 1.856 1.836 -0.066
ENSG00000149428 E010 0.9643800 1.886659e-02 5.688640e-01 0.8060611006 11 119045655 119045780 126 - 0.315 0.224 -0.655
ENSG00000149428 E011 67.1144951 2.263426e-04 7.248687e-01 0.8895262272 11 119045781 119045831 51 - 1.811 1.825 0.049
ENSG00000149428 E012 8.0410082 8.027970e-03 2.087896e-01 0.4928502467 11 119045832 119045834 3 - 0.889 1.020 0.489
ENSG00000149428 E013 61.6929764 3.041871e-04 5.501822e-01 0.7946935101 11 119046417 119046462 46 - 1.771 1.796 0.084
ENSG00000149428 E014 43.9081903 3.339947e-04 5.679295e-01 0.8055837128 11 119046463 119046467 5 - 1.644 1.618 -0.088
ENSG00000149428 E015 183.0178175 1.061719e-04 7.862981e-01 0.9176781180 11 119046562 119046802 241 - 2.245 2.252 0.025
ENSG00000149428 E016 0.7362855 3.921929e-02 4.482271e-01 0.7223745740 11 119046803 119046831 29 - 0.185 0.304 0.930
ENSG00000149428 E017 2.8372466 2.811332e-02 1.711417e-02 0.1143928284 11 119047170 119047733 564 - 0.414 0.758 1.567
ENSG00000149428 E018 88.2308714 1.761921e-03 2.044829e-02 0.1286882302 11 119047734 119047818 85 - 1.900 1.987 0.292
ENSG00000149428 E019 101.9428525 5.257081e-03 6.582114e-02 0.2584635934 11 119047947 119048080 134 - 1.965 2.045 0.268
ENSG00000149428 E020 0.7529996 1.409524e-02 1.492506e-02 0.1047464128 11 119048081 119048106 26 - 0.071 0.430 3.252
ENSG00000149428 E021 82.7869340 2.146313e-04 6.834524e-02 0.2638605855 11 119048248 119048356 109 - 1.882 1.945 0.213
ENSG00000149428 E022 38.0811931 3.696776e-04 3.652759e-01 0.6538162158 11 119048357 119048359 3 - 1.558 1.604 0.158
ENSG00000149428 E023 39.1842892 3.449393e-04 3.190824e-01 0.6118226311 11 119048360 119048370 11 - 1.568 1.618 0.171
ENSG00000149428 E024 0.8498655 2.032925e-01 6.676060e-01 0.8616095115 11 119048371 119048475 105 - 0.233 0.304 0.516
ENSG00000149428 E025 66.4445557 2.317290e-04 6.968458e-01 0.8762517017 11 119048476 119048563 88 - 1.817 1.803 -0.047
ENSG00000149428 E026 89.3625737 2.739788e-04 4.051432e-01 0.6878847592 11 119048714 119048886 173 - 1.928 1.957 0.097
ENSG00000149428 E027 40.3896918 5.462011e-03 4.756746e-01 0.7423355690 11 119049018 119049050 33 - 1.614 1.574 -0.136
ENSG00000149428 E028 81.7246226 1.958734e-04 2.177876e-01 0.5042907849 11 119049051 119049203 153 - 1.915 1.873 -0.141
ENSG00000149428 E029 1.2044588 1.135326e-02 7.657017e-01 0.9089250813 11 119049204 119049370 167 - 0.350 0.304 -0.292
ENSG00000149428 E030 55.7880429 7.424903e-03 2.395215e-01 0.5285740631 11 119049556 119049635 80 - 1.759 1.696 -0.213
ENSG00000149428 E031 0.1186381 1.178636e-02 1.000000e+00   11 119049636 119049776 141 - 0.071 0.000 -10.942
ENSG00000149428 E032 50.7826098 1.251965e-03 2.739499e-02 0.1541011046 11 119049777 119049837 61 - 1.731 1.629 -0.347
ENSG00000149428 E033 80.6065497 2.594775e-04 1.014958e-01 0.3326519092 11 119051035 119051173 139 - 1.914 1.857 -0.192
ENSG00000149428 E034 102.3534880 4.258868e-04 5.819300e-01 0.8138722833 11 119051438 119051625 188 - 2.003 1.987 -0.055
ENSG00000149428 E035 78.1991406 2.099751e-04 2.080662e-01 0.4917976929 11 119051819 119051951 133 - 1.897 1.853 -0.148
ENSG00000149428 E036 51.9073252 4.049926e-03 1.087983e-02 0.0850054997 11 119052090 119052172 83 - 1.749 1.618 -0.444
ENSG00000149428 E037 58.9013737 1.346411e-03 2.764346e-03 0.0324678185 11 119052295 119052429 135 - 1.803 1.672 -0.446
ENSG00000149428 E038 73.2502677 5.922290e-04 1.425145e-03 0.0196582571 11 119052637 119052829 193 - 1.894 1.772 -0.412
ENSG00000149428 E039 32.9449652 4.403655e-04 1.533519e-03 0.0208177165 11 119054121 119054187 67 - 1.570 1.392 -0.613
ENSG00000149428 E040 27.2012998 5.440666e-04 1.644661e-02 0.1115482009 11 119054188 119054236 49 - 1.481 1.335 -0.506
ENSG00000149428 E041 40.4981952 3.485087e-04 2.121283e-02 0.1317353774 11 119054494 119054584 91 - 1.639 1.524 -0.392
ENSG00000149428 E042 41.2887265 1.101681e-03 8.610953e-01 0.9518539490 11 119054585 119054675 91 - 1.612 1.604 -0.026
ENSG00000149428 E043 1.4852616 1.291946e-02 2.593720e-02 0.1489297075 11 119054676 119054983 308 - 0.233 0.569 1.930
ENSG00000149428 E044 38.8544534 4.176205e-03 8.633628e-01 0.9527895762 11 119054984 119055056 73 - 1.587 1.578 -0.030
ENSG00000149428 E045 17.7758969 5.037523e-03 6.647955e-01 0.8606389167 11 119055057 119055060 4 - 1.268 1.236 -0.115
ENSG00000149428 E046 0.2346346 1.559738e-02 5.567094e-01   11 119055061 119055154 94 - 0.132 0.000 -11.878
ENSG00000149428 E047 0.1265070 1.230034e-02 2.708519e-01   11 119055155 119055184 30 - 0.000 0.126 11.427
ENSG00000149428 E048 23.3094270 2.470801e-03 3.388683e-01 0.6305511559 11 119055185 119055201 17 - 1.391 1.328 -0.219
ENSG00000149428 E049 59.3013248 1.696825e-03 2.017136e-01 0.4840897802 11 119055202 119055339 138 - 1.782 1.727 -0.186
ENSG00000149428 E050 0.1186381 1.178636e-02 1.000000e+00   11 119055340 119055418 79 - 0.071 0.000 -10.942
ENSG00000149428 E051 47.3550088 2.975438e-04 6.036696e-03 0.0567613602 11 119055493 119055571 79 - 1.709 1.582 -0.433
ENSG00000149428 E052 1.2310817 4.114133e-01 3.973060e-01 0.6814751236 11 119055572 119055749 178 - 0.233 0.481 1.514
ENSG00000149428 E053 41.7539907 3.474030e-03 7.581459e-02 0.2813391928 11 119055750 119055843 94 - 1.646 1.550 -0.329
ENSG00000149428 E054 29.9977144 1.269224e-02 7.986729e-01 0.9243031362 11 119056070 119056167 98 - 1.481 1.463 -0.061
ENSG00000149428 E055 0.4989795 3.072252e-02 1.057740e-01   11 119056279 119056405 127 - 0.071 0.304 2.515
ENSG00000149428 E056 0.0000000       11 119056406 119056418 13 -      
ENSG00000149428 E057 0.8511214 1.364516e-02 6.504091e-01 0.8528229435 11 119056805 119057000 196 - 0.233 0.304 0.515
ENSG00000149428 E058 0.0000000       11 119057001 119057019 19 -      
ENSG00000149428 E059 3.5012286 1.550305e-01 9.949102e-01 1.0000000000 11 119057020 119057026 7 - 0.658 0.606 -0.222
ENSG00000149428 E060 5.9102648 6.942000e-02 5.544837e-01 0.7972862273 11 119057027 119057074 48 - 0.858 0.758 -0.392
ENSG00000149428 E061 4.4499394 4.884707e-02 2.572086e-01 0.5495292702 11 119057075 119057152 78 - 0.776 0.606 -0.708
ENSG00000149428 E062 3.9065700 8.383166e-03 1.612318e-01 0.4293622572 11 119057153 119057227 75 - 0.604 0.783 0.749

Help

Please Click HERE to learn more details about the results from DEXseq.