ENSG00000149480

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000278823 ENSG00000149480 No_inf pgKDN_inf MTA2 protein_coding protein_coding 53.94067 54.60915 52.42699 2.143527 2.135461 -0.05882204 27.630339 16.707464 35.304552 1.0492476 4.7869925 1.0789068 0.51684167 0.307325 0.680500 0.373175 0.01969752 0.01969752 FALSE TRUE
ENST00000524902 ENSG00000149480 No_inf pgKDN_inf MTA2 protein_coding protein_coding 53.94067 54.60915 52.42699 2.143527 2.135461 -0.05882204 11.172232 18.085886 8.309903 1.1595532 4.8285519 -1.1210231 0.20567500 0.330900 0.153650 -0.177250 0.44936441 0.01969752 FALSE TRUE
ENST00000526844 ENSG00000149480 No_inf pgKDN_inf MTA2 protein_coding retained_intron 53.94067 54.60915 52.42699 2.143527 2.135461 -0.05882204 2.989121 4.300931 1.438873 0.8074483 0.2755268 -1.5730685 0.05464167 0.077650 0.027475 -0.050175 0.25857767 0.01969752 FALSE FALSE
ENST00000527204 ENSG00000149480 No_inf pgKDN_inf MTA2 protein_coding protein_coding 53.94067 54.60915 52.42699 2.143527 2.135461 -0.05882204 3.365543 3.534199 2.507837 0.7116007 1.1315851 -0.4932749 0.06260000 0.064950 0.047175 -0.017775 0.82962580 0.01969752 FALSE TRUE
ENST00000531261 ENSG00000149480 No_inf pgKDN_inf MTA2 protein_coding retained_intron 53.94067 54.60915 52.42699 2.143527 2.135461 -0.05882204 4.489672 6.149969 2.904773 1.5886736 0.7175090 -1.0795397 0.08145000 0.111150 0.054100 -0.057050 0.55440581 0.01969752   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149480 E001 0.1271363 0.0126130943 0.506581983   11 62593214 62593214 1 - 0.000 0.098 10.354
ENSG00000149480 E002 70.8080576 0.0002792941 0.369311213 0.65754757 11 62593215 62593841 627 - 1.840 1.871 0.106
ENSG00000149480 E003 78.2743949 0.0002237085 0.906728814 0.97026927 11 62593842 62594040 199 - 1.901 1.897 -0.013
ENSG00000149480 E004 66.8509742 0.0003226604 0.087594716 0.30671518 11 62594259 62594407 149 - 1.799 1.861 0.208
ENSG00000149480 E005 56.8259649 0.0002864369 0.453734862 0.72640513 11 62594516 62594634 119 - 1.747 1.776 0.098
ENSG00000149480 E006 47.8320233 0.0002998456 0.157068920 0.42348694 11 62594981 62595070 90 - 1.657 1.718 0.204
ENSG00000149480 E007 79.7553063 0.0044139143 0.443840633 0.71849508 11 62595264 62595492 229 - 1.891 1.923 0.108
ENSG00000149480 E008 0.6149137 0.0285607409 0.611216289 0.83087050 11 62595748 62595751 4 - 0.169 0.245 0.671
ENSG00000149480 E009 53.7642454 0.0002679845 0.494452676 0.75596051 11 62595752 62595891 140 - 1.725 1.752 0.092
ENSG00000149480 E010 44.6038381 0.0003780841 0.374278504 0.66199904 11 62596010 62596107 98 - 1.639 1.678 0.133
ENSG00000149480 E011 27.3651632 0.0005178200 0.237740859 0.52671358 11 62596279 62596337 59 - 1.418 1.484 0.228
ENSG00000149480 E012 1.3635650 0.1592641984 0.462700111 0.73298987 11 62596338 62596457 120 - 0.290 0.442 0.893
ENSG00000149480 E013 37.0401977 0.0004270304 0.817687033 0.93361564 11 62596458 62596532 75 - 1.586 1.575 -0.038
ENSG00000149480 E014 2.1209445 0.0082624805 0.020110733 0.12740822 11 62596533 62596636 104 - 0.290 0.631 1.786
ENSG00000149480 E015 51.4088050 0.0006641200 0.370780949 0.65898850 11 62596637 62596765 129 - 1.738 1.700 -0.127
ENSG00000149480 E016 31.5410218 0.0004244673 0.788458152 0.91890468 11 62596766 62596825 60 - 1.520 1.505 -0.049
ENSG00000149480 E017 40.4109996 0.0007807471 0.011806725 0.08967247 11 62597316 62597415 100 - 1.673 1.554 -0.406
ENSG00000149480 E018 5.8459080 0.0312950356 0.004736445 0.04765071 11 62597416 62597609 194 - 0.612 0.981 1.472
ENSG00000149480 E019 39.6391449 0.0062776476 0.008759178 0.07353175 11 62597610 62597712 103 - 1.677 1.529 -0.507
ENSG00000149480 E020 35.0888284 0.0024680647 0.716842268 0.88590720 11 62598024 62598108 85 - 1.567 1.548 -0.065
ENSG00000149480 E021 21.4498822 0.0046083024 0.480571891 0.74589670 11 62598109 62598141 33 - 1.326 1.375 0.168
ENSG00000149480 E022 2.8642208 0.0048766498 0.014226933 0.10137664 11 62598142 62598288 147 - 0.385 0.723 1.588
ENSG00000149480 E023 0.8696264 0.0128067260 0.224273785 0.51180764 11 62598289 62598326 38 - 0.169 0.354 1.408
ENSG00000149480 E024 31.6008783 0.0004625055 0.546623157 0.79234502 11 62598327 62598390 64 - 1.497 1.529 0.108
ENSG00000149480 E025 1.8671413 0.0201225495 0.057911123 0.24087133 11 62598391 62598521 131 - 0.290 0.577 1.545
ENSG00000149480 E026 43.2977519 0.0011554350 0.891808777 0.96407798 11 62598522 62598639 118 - 1.643 1.650 0.021
ENSG00000149480 E027 0.2542726 0.3711338816 0.303992504   11 62599218 62599317 100 - 0.000 0.177 11.359
ENSG00000149480 E028 32.1067661 0.0039550881 0.025059904 0.14562879 11 62600166 62600259 94 - 1.581 1.451 -0.445
ENSG00000149480 E029 0.3731628 0.2150699068 0.601839614   11 62600260 62600346 87 - 0.093 0.177 1.086
ENSG00000149480 E030 25.1825735 0.0005573984 0.031604012 0.16793406 11 62600622 62600689 68 - 1.477 1.351 -0.436
ENSG00000149480 E031 2.1929696 0.0071626973 0.734388114 0.89458865 11 62601023 62601422 400 - 0.528 0.480 -0.236
ENSG00000149480 E032 39.0339495 0.0004551013 0.003839351 0.04129867 11 62601423 62601865 443 - 1.666 1.529 -0.469

Help

Please Click HERE to learn more details about the results from DEXseq.