ENSG00000149483

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000278826 ENSG00000149483 No_inf pgKDN_inf TMEM138 protein_coding protein_coding 46.63602 22.79028 54.19574 0.8081583 2.911052 1.249394 27.848118 13.883464 29.917464 1.8689156 2.1148875 1.1070637 0.60075833 0.604100 0.559475 -0.044625 8.623114e-01 3.314214e-06 FALSE TRUE
ENST00000451389 ENSG00000149483 No_inf pgKDN_inf TMEM138 protein_coding protein_coding 46.63602 22.79028 54.19574 0.8081583 2.911052 1.249394 3.050537 1.114509 4.071542 0.3300928 0.5263725 1.8598187 0.06270000 0.049625 0.075950 0.026325 8.135370e-01 3.314214e-06 FALSE FALSE
ENST00000542946 ENSG00000149483 No_inf pgKDN_inf TMEM138 protein_coding protein_coding 46.63602 22.79028 54.19574 0.8081583 2.911052 1.249394 2.669773 3.070431 1.838150 0.4761974 0.4040509 -0.7370505 0.07430833 0.137200 0.034450 -0.102750 9.000584e-02 3.314214e-06 FALSE FALSE
ENST00000545420 ENSG00000149483 No_inf pgKDN_inf TMEM138 protein_coding protein_coding_CDS_not_defined 46.63602 22.79028 54.19574 0.8081583 2.911052 1.249394 4.611448 0.000000 8.207113 0.0000000 2.4522101 9.6824877 0.07561667 0.000000 0.146575 0.146575 3.314214e-06 3.314214e-06 FALSE FALSE
ENST00000691720 ENSG00000149483 No_inf pgKDN_inf TMEM138 protein_coding protein_coding 46.63602 22.79028 54.19574 0.8081583 2.911052 1.249394 2.238617 1.565805 2.426868 0.4038216 0.1855551 0.6289387 0.05325000 0.070425 0.044625 -0.025800 8.414005e-01 3.314214e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149483 E001 0.0000000       11 61361964 61362152 189 +      
ENSG00000149483 E002 0.5995554 0.0149856640 3.918773e-01 6.769622e-01 11 61362153 61362343 191 + 0.248 0.117 -1.312
ENSG00000149483 E003 1.0905400 0.0269157478 7.576223e-01 9.047983e-01 11 61362344 61362360 17 + 0.334 0.286 -0.312
ENSG00000149483 E004 0.9718369 0.0143488173 9.579310e-01 9.899059e-01 11 61362361 61362366 6 + 0.293 0.286 -0.049
ENSG00000149483 E005 1.0986909 0.0113535919 7.148047e-01 8.850613e-01 11 61362367 61362373 7 + 0.293 0.351 0.366
ENSG00000149483 E006 1.2156949 0.0104736787 9.180100e-01 9.742228e-01 11 61362374 61362377 4 + 0.334 0.351 0.103
ENSG00000149483 E007 2.8202564 0.0051120439 1.853028e-01 4.630338e-01 11 61362378 61362380 3 + 0.494 0.675 0.814
ENSG00000149483 E008 3.5618928 0.0082014478 7.509754e-02 2.796790e-01 11 61362381 61362385 5 + 0.545 0.776 0.988
ENSG00000149483 E009 5.9739217 0.0024219001 3.563479e-01 6.461310e-01 11 61362386 61362396 11 + 0.793 0.894 0.393
ENSG00000149483 E010 8.0018001 0.0017510053 7.347545e-01 8.947448e-01 11 61362397 61362409 13 + 0.959 0.927 -0.119
ENSG00000149483 E011 9.3522715 0.0015088173 9.181732e-01 9.743084e-01 11 61362410 61362420 11 + 1.003 1.014 0.040
ENSG00000149483 E012 0.2363338 0.0157018088 4.524972e-01   11 61362421 61362432 12 + 0.142 0.000 -11.058
ENSG00000149483 E013 1.0822017 0.0124409116 3.061383e-01 5.992866e-01 11 61362433 61362625 193 + 0.371 0.210 -1.119
ENSG00000149483 E014 0.4833718 0.4417003020 8.322387e-01   11 61362626 61362668 43 + 0.198 0.118 -0.899
ENSG00000149483 E015 0.8640860 0.0183795511 3.231186e-01 6.158517e-01 11 61362669 61363498 830 + 0.198 0.351 1.103
ENSG00000149483 E016 2.2947471 0.0072455251 5.428262e-01 7.899832e-01 11 61363499 61363868 370 + 0.545 0.457 -0.427
ENSG00000149483 E017 0.3561095 0.5245982448 4.774605e-01   11 61363869 61364249 381 + 0.199 0.000 -10.725
ENSG00000149483 E018 0.1187032 0.0117994789 9.043968e-01   11 61364250 61364251 2 + 0.077 0.000 -10.143
ENSG00000149483 E019 16.2702356 0.0009544872 9.194221e-01 9.748390e-01 11 61364252 61364315 64 + 1.226 1.234 0.031
ENSG00000149483 E020 30.5704221 0.0088673541 1.241907e-01 3.734082e-01 11 61364316 61364432 117 + 1.529 1.428 -0.346
ENSG00000149483 E021 37.0776957 0.0075549583 6.119767e-02 2.484477e-01 11 61364433 61364518 86 + 1.614 1.502 -0.382
ENSG00000149483 E022 1.7040912 0.0222963622 7.451056e-01 8.991635e-01 11 61364519 61364870 352 + 0.405 0.457 0.273
ENSG00000149483 E023 0.7144144 0.0143225388 2.562139e-01 5.482762e-01 11 61365703 61366044 342 + 0.293 0.117 -1.634
ENSG00000149483 E024 55.3649202 0.0015419377 1.276218e-04 2.894515e-03 11 61366045 61366216 172 + 1.800 1.639 -0.545
ENSG00000149483 E025 10.5319013 0.0179381748 8.901708e-06 3.087490e-04 11 61366217 61366978 762 + 0.819 1.265 1.637
ENSG00000149483 E026 7.8311642 0.0119348627 8.785735e-07 4.163883e-05 11 61366979 61367427 449 + 0.650 1.175 2.010
ENSG00000149483 E027 6.7902432 0.0489987898 7.677329e-03 6.721222e-02 11 61367428 61367904 477 + 0.703 1.063 1.383
ENSG00000149483 E028 1.5788826 0.0085946468 9.958814e-01 1.000000e+00 11 61367905 61367922 18 + 0.405 0.407 0.010
ENSG00000149483 E029 31.9971837 0.0005522599 6.446273e-03 5.942117e-02 11 61367923 61367998 76 + 1.562 1.418 -0.496
ENSG00000149483 E030 5.1776201 0.0675471149 6.566337e-02 2.581259e-01 11 61367999 61368251 253 + 0.651 0.927 1.103
ENSG00000149483 E031 2.9442395 0.0387443101 2.927645e-01 5.863117e-01 11 61368252 61368269 18 + 0.520 0.675 0.688
ENSG00000149483 E032 9.6017787 0.0025815734 1.475375e-03 2.019104e-02 11 61368270 61368596 327 + 0.878 1.166 1.060
ENSG00000149483 E033 11.7164182 0.0012755118 2.003751e-01 4.823481e-01 11 61368597 61368599 3 + 1.050 1.157 0.386
ENSG00000149483 E034 38.5520335 0.0003875494 3.968197e-01 6.813362e-01 11 61368600 61368771 172 + 1.604 1.565 -0.132
ENSG00000149483 E035 77.9826587 0.0003093486 8.187139e-01 9.339542e-01 11 61368772 61369509 738 + 1.885 1.894 0.030
ENSG00000149483 E036 5.0823021 0.0028477176 5.010167e-01 7.610821e-01 11 61373043 61373492 450 + 0.806 0.728 -0.312
ENSG00000149483 E037 13.2840608 0.0067481099 2.660158e-01 5.594579e-01 11 61376463 61377890 1428 + 1.106 1.202 0.342

Help

Please Click HERE to learn more details about the results from DEXseq.