ENSG00000149532

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000394888 ENSG00000149532 No_inf pgKDN_inf CPSF7 protein_coding protein_coding 39.46614 42.68904 36.27531 0.7459317 1.129674 -0.2348178 12.908698 13.11712 13.409762 1.431824 1.8621647 0.03180898 0.3298583 0.307350 0.369525 0.062175 0.834313651 0.003655395 FALSE TRUE
ENST00000439958 ENSG00000149532 No_inf pgKDN_inf CPSF7 protein_coding protein_coding 39.46614 42.68904 36.27531 0.7459317 1.129674 -0.2348178 14.261844 10.96389 16.016108 1.465364 1.1638871 0.54634913 0.3677333 0.258550 0.443875 0.185325 0.179511964 0.003655395 FALSE TRUE
MSTRG.4807.3 ENSG00000149532 No_inf pgKDN_inf CPSF7 protein_coding   39.46614 42.68904 36.27531 0.7459317 1.129674 -0.2348178 5.026139 11.17061 1.289759 1.770695 0.7035767 -3.10468181 0.1205583 0.260075 0.034700 -0.225375 0.003655395 0.003655395 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149532 E001 0.1272623 1.233398e-02 7.106498e-01   11 61402641 61402648 8 - 0.000 0.084 9.616
ENSG00000149532 E002 1.3316289 1.217566e-01 2.358844e-01 5.252545e-01 11 61402649 61402720 72 - 0.472 0.268 -1.206
ENSG00000149532 E003 2.5841723 5.526471e-03 9.859054e-01 9.991944e-01 11 61402721 61402728 8 - 0.548 0.551 0.015
ENSG00000149532 E004 328.2324991 7.433238e-05 3.134443e-01 6.065839e-01 11 61402729 61404287 1559 - 2.502 2.517 0.051
ENSG00000149532 E005 44.2369345 5.284322e-04 4.529954e-01 7.258640e-01 11 61404288 61404418 131 - 1.668 1.635 -0.110
ENSG00000149532 E006 67.3859244 3.446216e-04 4.816778e-02 2.160147e-01 11 61404419 61404704 286 - 1.868 1.798 -0.237
ENSG00000149532 E007 2.4869609 5.780798e-03 2.357276e-01 5.250489e-01 11 61405932 61406170 239 - 0.429 0.600 0.823
ENSG00000149532 E008 1.7521896 1.098721e-01 1.556100e-01 4.215305e-01 11 61410572 61410937 366 - 0.266 0.524 1.475
ENSG00000149532 E009 27.5974232 1.168587e-03 1.810066e-01 4.568279e-01 11 61410938 61411006 69 - 1.492 1.417 -0.258
ENSG00000149532 E010 28.8275778 6.466707e-04 1.562736e-01 4.225429e-01 11 61411007 61411105 99 - 1.512 1.435 -0.264
ENSG00000149532 E011 34.7325347 4.137828e-04 7.724180e-01 9.123428e-01 11 61411769 61411937 169 - 1.537 1.553 0.054
ENSG00000149532 E012 26.8757062 5.720367e-04 5.072692e-01 7.657476e-01 11 61415666 61415784 119 - 1.415 1.455 0.136
ENSG00000149532 E013 14.2451148 7.546031e-03 1.925916e-12 2.410032e-10 11 61415785 61416104 320 - 0.641 1.353 2.674
ENSG00000149532 E014 17.5452585 4.011665e-03 2.511107e-01 5.423220e-01 11 61416105 61416162 58 - 1.209 1.296 0.305
ENSG00000149532 E015 11.6782288 5.896917e-03 2.156645e-02 1.330146e-01 11 61416163 61416177 15 - 0.962 1.172 0.765
ENSG00000149532 E016 9.7917631 1.368023e-02 1.524062e-01 4.163650e-01 11 61416178 61416178 1 - 0.934 1.082 0.546
ENSG00000149532 E017 24.4321025 6.118755e-04 3.700961e-01 6.584017e-01 11 61416179 61416296 118 - 1.366 1.421 0.191
ENSG00000149532 E018 14.1476149 9.742738e-04 7.801496e-01 9.152571e-01 11 61416297 61416363 67 - 1.186 1.166 -0.072
ENSG00000149532 E019 7.1544596 2.248634e-03 7.989640e-01 9.245007e-01 11 61416364 61416368 5 - 0.889 0.916 0.103
ENSG00000149532 E020 7.7689270 2.311090e-03 7.776047e-01 9.146684e-01 11 61416369 61416384 16 - 0.920 0.949 0.109
ENSG00000149532 E021 11.6073659 4.326333e-02 5.694545e-01 8.064269e-01 11 61416385 61416428 44 - 1.057 1.119 0.224
ENSG00000149532 E022 14.4414219 9.462537e-04 4.161404e-01 6.960063e-01 11 61416429 61416464 36 - 1.144 1.208 0.227
ENSG00000149532 E023 13.7675667 1.214485e-03 5.986887e-01 8.240431e-01 11 61416465 61416499 35 - 1.186 1.146 -0.141
ENSG00000149532 E024 14.4352205 9.548657e-04 6.073202e-02 2.474121e-01 11 61416500 61416519 20 - 1.259 1.119 -0.497
ENSG00000149532 E025 5.7018364 2.508335e-03 4.635570e-03 4.690710e-02 11 61419922 61419948 27 - 0.975 0.665 -1.219
ENSG00000149532 E026 14.1559029 2.164225e-03 1.046983e-02 8.272486e-02 11 61419949 61419969 21 - 1.279 1.082 -0.699
ENSG00000149532 E027 19.7005431 6.976043e-04 4.515664e-02 2.077939e-01 11 61419970 61420030 61 - 1.381 1.251 -0.453
ENSG00000149532 E028 11.5041523 1.194358e-03 1.213261e-01 3.687367e-01 11 61420031 61420034 4 - 1.161 1.034 -0.461
ENSG00000149532 E029 11.6240780 1.886964e-03 1.002349e-01 3.307809e-01 11 61420035 61420040 6 - 1.170 1.034 -0.491
ENSG00000149532 E030 12.0136032 3.970595e-02 3.557286e-01 6.455136e-01 11 61420041 61420056 16 - 1.161 1.066 -0.341
ENSG00000149532 E031 10.5695158 3.534208e-02 6.977575e-01 8.766455e-01 11 61420057 61420057 1 - 1.078 1.042 -0.131
ENSG00000149532 E032 17.2300503 2.353677e-03 9.039641e-01 9.690774e-01 11 61420058 61420094 37 - 1.259 1.251 -0.027
ENSG00000149532 E033 15.7384543 8.800403e-04 7.360237e-01 8.952192e-01 11 61420470 61420493 24 - 1.231 1.208 -0.083
ENSG00000149532 E034 15.4303568 9.423986e-04 2.945398e-01 5.879575e-01 11 61420494 61420530 37 - 1.161 1.241 0.282
ENSG00000149532 E035 10.9842261 1.761835e-02 4.261000e-01 7.049033e-01 11 61420531 61420546 16 - 1.023 1.105 0.295
ENSG00000149532 E036 11.8979643 2.777319e-02 6.245863e-01 8.385050e-01 11 61420547 61420573 27 - 1.135 1.082 -0.190
ENSG00000149532 E037 2.9578448 5.339767e-03 8.923117e-01 9.641748e-01 11 61420574 61420992 419 - 0.581 0.600 0.086
ENSG00000149532 E038 1.1178855 1.255754e-02 5.566464e-01 7.988483e-01 11 61420993 61421053 61 - 0.266 0.358 0.600
ENSG00000149532 E039 2.8333461 5.250168e-03 9.665971e-01 9.932828e-01 11 61421054 61421127 74 - 0.581 0.576 -0.021
ENSG00000149532 E040 1.5890796 3.343820e-02 4.535084e-01 7.261898e-01 11 61421128 61421130 3 - 0.472 0.358 -0.622
ENSG00000149532 E041 1.2354246 1.219333e-02 8.482816e-01 9.462857e-01 11 61421131 61421191 61 - 0.327 0.358 0.185
ENSG00000149532 E042 1.3785810 9.491155e-03 8.300359e-02 2.969038e-01 11 61421192 61421224 33 - 0.194 0.465 1.770
ENSG00000149532 E043 1.6406575 9.408270e-03 4.900263e-03 4.886130e-02 11 61421225 61421257 33 - 0.108 0.551 3.185
ENSG00000149532 E044 1.2591226 1.448823e-02 2.360529e-02 1.404908e-01 11 61421258 61421313 56 - 0.108 0.465 2.770
ENSG00000149532 E045 1.7492284 7.825611e-03 9.275963e-02 3.162512e-01 11 61421314 61421389 76 - 0.266 0.524 1.475
ENSG00000149532 E046 9.9445415 1.056603e-02 6.540277e-01 8.547623e-01 11 61421390 61421394 5 - 1.057 1.016 -0.149
ENSG00000149532 E047 39.5170915 3.518520e-04 8.929924e-01 9.645020e-01 11 61421395 61421608 214 - 1.597 1.604 0.026
ENSG00000149532 E048 0.0000000       11 61428898 61429181 284 -      
ENSG00000149532 E049 7.8586831 6.104728e-03 5.586775e-01 8.002049e-01 11 61429182 61429290 109 - 0.975 0.916 -0.219
ENSG00000149532 E050 0.0000000       11 61429291 61429304 14 -      
ENSG00000149532 E051 0.7523083 1.408281e-02 1.755422e-01 4.496125e-01 11 61429450 61429634 185 - 0.108 0.315 1.922
ENSG00000149532 E052 0.2543986 1.599809e-02 3.539158e-01   11 61429635 61429756 122 - 0.000 0.154 12.824
ENSG00000149532 E053 0.2346346 1.561981e-02 1.605313e-01   11 61429757 61429840 84 - 0.194 0.000 -14.066
ENSG00000149532 E054 0.2346346 1.561981e-02 1.605313e-01   11 61429841 61429886 46 - 0.194 0.000 -14.066
ENSG00000149532 E055 0.1176306 1.174551e-02 4.046839e-01   11 61429887 61429913 27 - 0.108 0.000 -13.128
ENSG00000149532 E056 0.3707734 1.678288e-02 7.712026e-01   11 61429914 61430031 118 - 0.108 0.154 0.600

Help

Please Click HERE to learn more details about the results from DEXseq.