ENSG00000149541

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265471 ENSG00000149541 No_inf pgKDN_inf B3GAT3 protein_coding protein_coding 55.36591 42.14786 59.00839 0.5720462 1.426526 0.485363 49.168535 37.24232 49.399484 0.7863741 2.40250 0.4074577 0.8866833 0.883775 0.839675 -0.044100 0.8512893652 0.0001468517 FALSE  
MSTRG.4849.1 ENSG00000149541 No_inf pgKDN_inf B3GAT3 protein_coding   55.36591 42.14786 59.00839 0.5720462 1.426526 0.485363 1.592427 0.00000 4.777281 0.0000000 2.15624 8.9030625 0.0267250 0.000000 0.080175 0.080175 0.0001468517 0.0001468517 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149541 E001 0.2451451 0.0160546673 0.881960173   11 62615296 62615296 1 - 0.087 0.104 0.278
ENSG00000149541 E002 4.5116047 0.0195278159 0.815128823 0.93239552 11 62615297 62615331 35 - 0.754 0.725 -0.115
ENSG00000149541 E003 28.4653248 0.0005453757 0.728998177 0.89194410 11 62615332 62615450 119 - 1.459 1.479 0.067
ENSG00000149541 E004 123.9941827 0.0001862629 0.058222875 0.24159889 11 62615451 62615799 349 - 2.074 2.120 0.153
ENSG00000149541 E005 0.8781246 0.0123216871 0.027632607 0.15504872 11 62615800 62616066 267 - 0.087 0.418 2.863
ENSG00000149541 E006 0.8807964 0.0124712493 0.027564405 0.15484832 11 62616067 62616236 170 - 0.087 0.418 2.863
ENSG00000149541 E007 0.2459004 0.0160861633 0.881877448   11 62616237 62616240 4 - 0.087 0.104 0.278
ENSG00000149541 E008 94.5768903 0.0001701517 0.974629705 0.99541136 11 62616506 62616688 183 - 1.979 1.980 0.005
ENSG00000149541 E009 54.2736795 0.0003401386 0.094658903 0.32014900 11 62616689 62616796 108 - 1.771 1.706 -0.219
ENSG00000149541 E010 1.7610584 0.0120249357 0.001913597 0.02473892 11 62616797 62616986 190 - 0.160 0.627 2.863
ENSG00000149541 E011 22.5071617 0.0011956919 0.255095077 0.54702787 11 62616987 62617004 18 - 1.402 1.332 -0.242
ENSG00000149541 E012 71.4905614 0.0002701652 0.197097991 0.47828143 11 62617005 62617337 333 - 1.879 1.837 -0.143
ENSG00000149541 E013 12.9321921 0.0048463326 0.996466795 1.00000000 11 62617338 62617347 10 - 1.143 1.144 0.005
ENSG00000149541 E014 2.2194738 0.0096460917 0.184530326 0.46168954 11 62617348 62617454 107 - 0.408 0.598 0.930
ENSG00000149541 E015 23.5563664 0.0009082935 0.964544643 0.99251477 11 62620497 62620671 175 - 1.390 1.388 -0.007
ENSG00000149541 E016 0.8630749 0.0136619433 0.531595415 0.78218707 11 62621055 62621123 69 - 0.222 0.318 0.693
ENSG00000149541 E017 2.4482836 0.0063409601 0.672829735 0.86447161 11 62621124 62621293 170 - 0.508 0.568 0.278
ENSG00000149541 E018 9.9798183 0.0014078550 0.492142490 0.75441147 11 62621866 62621875 10 - 1.067 1.007 -0.220
ENSG00000149541 E019 20.8589018 0.0050953136 0.741950130 0.89785138 11 62621876 62622154 279 - 1.349 1.327 -0.078

Help

Please Click HERE to learn more details about the results from DEXseq.