ENSG00000149571

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000525144 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding protein_coding 5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 0.7804370 1.1930358 0.0000000 0.02000759 0.00000000 -6.910536 0.16559167 0.328625 0.000000 -0.328625 0.0002346633 0.0002346633 FALSE TRUE
ENST00000525704 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding protein_coding 5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 0.3800102 0.0000000 0.6900028 0.00000000 0.10314382 6.129289 0.05877500 0.000000 0.112275 0.112275 0.1031497610 0.0002346633 FALSE TRUE
ENST00000526519 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding protein_coding_CDS_not_defined 5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 0.3184763 0.9554290 0.0000000 0.56016599 0.00000000 -6.593098 0.07222500 0.216675 0.000000 -0.216675 0.3723816289 0.0002346633 TRUE FALSE
ENST00000526764 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding retained_intron 5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 1.4294067 1.6438025 0.9498008 0.42389266 0.62119015 -0.784980 0.25947500 0.424725 0.134600 -0.290125 0.3776753303 0.0002346633   FALSE
ENST00000529097 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding protein_coding 5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 0.5315019 0.0000000 1.2982983 0.00000000 0.09845324 7.031548 0.08080833 0.000000 0.203600 0.203600 0.0077495452 0.0002346633 FALSE TRUE
MSTRG.5757.3 ENSG00000149571 No_inf pgKDN_inf KIRREL3 protein_coding   5.794322 3.926762 6.365268 0.6253363 0.3749097 0.6954763 2.3218695 0.1025551 3.4271661 0.10255513 0.29290609 4.932516 0.35820833 0.024075 0.549525 0.525450 0.0005654272 0.0002346633 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149571 E001 0.0000000       11 126423358 126423494 137 -      
ENSG00000149571 E002 19.2578450 0.001377621 3.251952e-05 9.240821e-04 11 126423495 126425023 1529 - 1.245 1.366 0.424
ENSG00000149571 E003 1.5918812 0.057269260 3.389889e-01 6.306449e-01 11 126425638 126425673 36 - 0.370 0.458 0.481
ENSG00000149571 E004 2.4876861 0.006779394 6.005753e-03 5.649011e-02 11 126425674 126425724 51 - 0.370 0.676 1.480
ENSG00000149571 E005 2.3533106 0.008568918 4.004253e-02 1.939578e-01 11 126429179 126429288 110 - 0.409 0.624 1.036
ENSG00000149571 E006 3.1911680 0.005243115 2.496632e-07 1.326634e-05 11 126430942 126431418 477 - 0.848 0.000 -16.091
ENSG00000149571 E007 3.0253292 0.005426017 4.101292e-01 6.921467e-01 11 126431419 126431526 108 - 0.682 0.497 -0.829
ENSG00000149571 E008 1.5892024 0.011292586 6.423460e-01 8.483168e-01 11 126435268 126435303 36 - 0.409 0.416 0.036
ENSG00000149571 E009 1.4533158 0.022784751 6.466160e-01 8.503871e-01 11 126436811 126436863 53 - 0.446 0.316 -0.742
ENSG00000149571 E010 2.9019123 0.005288598 5.016261e-01 7.615773e-01 11 126436864 126437009 146 - 0.661 0.497 -0.742
ENSG00000149571 E011 3.3510793 0.007152773 3.539217e-02 1.800563e-01 11 126440449 126440549 101 - 0.773 0.416 -1.616
ENSG00000149571 E012 1.7404156 0.008765730 1.652921e-02 1.119776e-01 11 126440550 126440818 269 - 0.278 0.565 1.580
ENSG00000149571 E013 0.4906372 0.018237174 6.815088e-01   11 126440822 126440850 29 - 0.161 0.186 0.258
ENSG00000149571 E014 0.3641302 0.087772596 8.920682e-01   11 126440851 126440882 32 - 0.161 0.103 -0.742
ENSG00000149571 E015 2.4751193 0.006375524 7.115014e-06 2.546588e-04 11 126444979 126445105 127 - 0.756 0.000 -15.757
ENSG00000149571 E016 3.6723338 0.005629950 8.859043e-07 4.194940e-05 11 126445452 126445837 386 - 0.887 0.103 -4.649
ENSG00000149571 E017 0.0000000       11 126446759 126446886 128 -      
ENSG00000149571 E018 0.0000000       11 126449009 126449157 149 -      
ENSG00000149571 E019 0.1268540 0.012506486 3.493372e-01   11 126456349 126456454 106 - 0.000 0.103 11.674
ENSG00000149571 E020 0.0000000       11 126463157 126463307 151 -      
ENSG00000149571 E021 0.1268540 0.012506486 3.493372e-01   11 126473309 126473466 158 - 0.000 0.103 11.674
ENSG00000149571 E022 0.0000000       11 126521315 126521464 150 -      
ENSG00000149571 E023 0.0000000       11 126526538 126526687 150 -      
ENSG00000149571 E024 0.0000000       11 126549284 126549417 134 -      
ENSG00000149571 E025 0.0000000       11 126549418 126549538 121 -      
ENSG00000149571 E026 0.0000000       11 126549539 126550647 1109 -      
ENSG00000149571 E027 0.0000000       11 126550648 126550651 4 -      
ENSG00000149571 E028 0.1268540 0.012506486 3.493372e-01   11 126562835 126562912 78 - 0.000 0.103 11.674
ENSG00000149571 E029 0.0000000       11 127000455 127000870 416 -      
ENSG00000149571 E030 0.0000000       11 127000871 127001165 295 -      
ENSG00000149571 E031 0.0000000       11 127003256 127003460 205 -      

Help

Please Click HERE to learn more details about the results from DEXseq.