ENSG00000149781

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000345728 ENSG00000149781 No_inf pgKDN_inf FERMT3 protein_coding protein_coding 339.3925 292.3997 386.2974 3.679298 10.21532 0.4017579 199.40891 148.449087 241.81481 4.976049 5.973806 0.7038969 0.5827083 0.50800 0.628075 0.120075 0.04958571 0.0242555 FALSE TRUE
ENST00000544997 ENSG00000149781 No_inf pgKDN_inf FERMT3 protein_coding protein_coding 339.3925 292.3997 386.2974 3.679298 10.21532 0.4017579 22.87781 6.214438 34.22096 2.618770 4.046155 2.4592865 0.0645250 0.02105 0.088675 0.067625 0.12459400 0.0242555 FALSE TRUE
ENST00000545896 ENSG00000149781 No_inf pgKDN_inf FERMT3 protein_coding protein_coding 339.3925 292.3997 386.2974 3.679298 10.21532 0.4017579 68.61981 87.142558 68.89874 3.215273 11.686761 -0.3388560 0.2067583 0.29775 0.176375 -0.121375 0.02425550 0.0242555 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000149781 E001 1.1239641 1.062619e-02 4.196600e-02 1.993477e-01 11 64205926 64206626 701 + 0.157 0.466 2.144
ENSG00000149781 E002 0.3622142 1.653658e-02 7.380510e-01   11 64206627 64206631 5 + 0.157 0.106 -0.663
ENSG00000149781 E003 0.7243294 1.389120e-02 5.912493e-01 8.192067e-01 11 64206632 64206664 33 + 0.272 0.190 -0.663
ENSG00000149781 E004 0.7243294 1.389120e-02 5.912493e-01 8.192067e-01 11 64206665 64206669 5 + 0.272 0.190 -0.663
ENSG00000149781 E005 0.9786020 1.201124e-02 7.445710e-01 8.987986e-01 11 64206670 64206688 19 + 0.272 0.322 0.337
ENSG00000149781 E006 0.6163879 2.097868e-01 5.232920e-01 7.766548e-01 11 64206689 64206691 3 + 0.157 0.261 0.922
ENSG00000149781 E007 1.0969880 1.515218e-02 9.877512e-01 9.998311e-01 11 64206692 64206702 11 + 0.320 0.322 0.015
ENSG00000149781 E008 2.4221653 6.136247e-03 4.094733e-01 6.917196e-01 11 64206703 64206710 8 + 0.583 0.466 -0.557
ENSG00000149781 E009 2.9139052 5.868754e-03 5.128548e-01 7.698185e-01 11 64206711 64206715 5 + 0.630 0.541 -0.400
ENSG00000149781 E010 3.0315359 5.170758e-03 4.121613e-01 6.935635e-01 11 64206716 64206720 5 + 0.652 0.541 -0.494
ENSG00000149781 E011 3.8750681 4.213453e-02 3.085486e-01 6.017886e-01 11 64206721 64206722 2 + 0.746 0.605 -0.596
ENSG00000149781 E012 4.1295928 2.498925e-02 5.122997e-01 7.692198e-01 11 64206723 64206725 3 + 0.746 0.660 -0.355
ENSG00000149781 E013 4.7370468 9.000468e-03 4.852782e-01 7.491634e-01 11 64206726 64206728 3 + 0.794 0.710 -0.341
ENSG00000149781 E014 6.0862035 2.941453e-03 7.584882e-01 9.051660e-01 11 64206729 64206731 3 + 0.864 0.831 -0.129
ENSG00000149781 E015 9.5266879 1.493405e-03 7.308762e-01 8.931073e-01 11 64206732 64206737 6 + 1.006 1.037 0.114
ENSG00000149781 E016 10.7443263 1.260010e-03 8.137271e-01 9.318715e-01 11 64206738 64206741 4 + 1.059 1.079 0.073
ENSG00000149781 E017 11.4781265 1.249751e-03 7.648354e-01 9.085086e-01 11 64206742 64206743 2 + 1.083 1.108 0.090
ENSG00000149781 E018 24.1568096 9.718542e-04 9.443063e-01 9.845722e-01 11 64206744 64206758 15 + 1.401 1.397 -0.015
ENSG00000149781 E019 55.7198395 2.565636e-04 1.251320e-01 3.749741e-01 11 64206759 64206814 56 + 1.780 1.717 -0.212
ENSG00000149781 E020 5.6678835 2.483756e-03 5.163841e-02 2.254566e-01 11 64206815 64207105 291 + 0.711 0.926 0.843
ENSG00000149781 E021 1.4965603 1.119045e-01 6.617524e-02 2.590406e-01 11 64207106 64207107 2 + 0.218 0.541 1.922
ENSG00000149781 E022 5.4589396 2.549970e-02 4.782112e-03 4.799375e-02 11 64207108 64207271 164 + 0.607 0.966 1.436
ENSG00000149781 E023 3.3023303 4.924799e-03 6.846876e-01 8.695679e-01 11 64207272 64207350 79 + 0.607 0.660 0.230
ENSG00000149781 E024 36.4415893 2.714204e-03 6.633103e-01 8.597841e-01 11 64207351 64207353 3 + 1.583 1.559 -0.081
ENSG00000149781 E025 43.0236860 1.367002e-03 5.980415e-02 2.452886e-01 11 64207354 64207356 3 + 1.682 1.591 -0.310
ENSG00000149781 E026 232.3001860 1.618614e-03 4.843052e-04 8.519413e-03 11 64207357 64207524 168 + 2.406 2.315 -0.301
ENSG00000149781 E027 3.9546956 3.698974e-03 4.035113e-02 1.947993e-01 11 64207525 64207730 206 + 0.558 0.813 1.073
ENSG00000149781 E028 1.4666586 9.312586e-03 6.898644e-01 8.725806e-01 11 64207731 64207771 41 + 0.363 0.423 0.337
ENSG00000149781 E029 2.3318473 5.885168e-03 4.668208e-01 7.354417e-01 11 64207772 64207906 135 + 0.471 0.574 0.489
ENSG00000149781 E030 0.4992000 4.444196e-01 4.331418e-01   11 64207907 64207970 64 + 0.086 0.261 1.920
ENSG00000149781 E031 0.3723461 2.104814e-01 5.018324e-01   11 64207971 64207975 5 + 0.086 0.190 1.336
ENSG00000149781 E032 1.5892969 9.368363e-03 8.888904e-01 9.629884e-01 11 64207976 64208219 244 + 0.402 0.423 0.114
ENSG00000149781 E033 7.3199518 1.022069e-01 2.212143e-02 1.351426e-01 11 64208220 64208798 579 + 0.692 1.089 1.524
ENSG00000149781 E034 12.5426946 1.938880e-03 2.185009e-07 1.174938e-05 11 64208799 64209530 732 + 0.877 1.312 1.579
ENSG00000149781 E035 14.5336729 7.791939e-03 2.944294e-07 1.544724e-05 11 64209531 64210610 1080 + 0.936 1.372 1.565
ENSG00000149781 E036 311.6367115 1.195392e-04 2.242567e-06 9.332608e-05 11 64210611 64210791 181 + 2.530 2.447 -0.276
ENSG00000149781 E037 134.4686802 2.745943e-03 2.529024e-02 1.463357e-01 11 64210792 64210844 53 + 2.164 2.087 -0.256
ENSG00000149781 E038 177.8590860 1.627188e-03 2.991649e-02 1.626681e-01 11 64211052 64211155 104 + 2.278 2.217 -0.207
ENSG00000149781 E039 95.2729883 1.773417e-04 4.498393e-01 7.233860e-01 11 64211156 64211171 16 + 1.993 1.969 -0.080
ENSG00000149781 E040 284.8122673 7.771054e-05 6.132106e-02 2.487062e-01 11 64211275 64211443 169 + 2.470 2.436 -0.112
ENSG00000149781 E041 2.9634401 6.500196e-02 1.391451e-01 3.966456e-01 11 64211444 64211575 132 + 0.471 0.710 1.073
ENSG00000149781 E042 1.4596377 4.318322e-02 8.699580e-01 9.552120e-01 11 64211576 64211644 69 + 0.402 0.376 -0.149
ENSG00000149781 E043 75.2691264 4.642733e-04 8.881996e-02 3.091987e-01 11 64211645 64211649 5 + 1.908 1.847 -0.206
ENSG00000149781 E044 198.6321562 1.073464e-04 2.423876e-02 1.426709e-01 11 64211650 64211747 98 + 2.321 2.272 -0.163
ENSG00000149781 E045 0.9806472 1.659795e-02 7.465488e-01 8.997024e-01 11 64211928 64211978 51 + 0.272 0.322 0.337
ENSG00000149781 E046 7.4625901 2.725784e-02 2.929903e-04 5.696517e-03 11 64217497 64218690 1194 + 0.672 1.108 1.675
ENSG00000149781 E047 2.9849950 3.258183e-02 1.594830e-02 1.095254e-01 11 64218691 64218896 206 + 0.402 0.754 1.616
ENSG00000149781 E048 2.8751397 6.259421e-03 1.025349e-03 1.528502e-02 11 64218897 64219229 333 + 0.320 0.775 2.184
ENSG00000149781 E049 1.9486449 9.291824e-03 9.723264e-01 9.947660e-01 11 64219230 64219250 21 + 0.471 0.466 -0.026
ENSG00000149781 E050 87.0793653 6.459452e-03 9.214462e-01 9.754795e-01 11 64219251 64219254 4 + 1.945 1.941 -0.013
ENSG00000149781 E051 238.3543261 8.041665e-05 1.218668e-01 3.693951e-01 11 64219255 64219358 104 + 2.391 2.361 -0.102
ENSG00000149781 E052 7.6421861 1.829403e-03 1.580202e-02 1.088463e-01 11 64219359 64219452 94 + 0.809 1.048 0.902
ENSG00000149781 E053 3.6202708 3.941319e-03 6.156524e-04 1.023570e-02 11 64219453 64219476 24 + 0.402 0.848 1.989
ENSG00000149781 E054 5.1253585 2.839462e-03 1.245635e-05 4.126664e-04 11 64219477 64219509 33 + 0.471 0.991 2.167
ENSG00000149781 E055 5.0968442 2.135838e-02 1.904784e-03 2.465386e-02 11 64219510 64219523 14 + 0.558 0.953 1.609
ENSG00000149781 E056 293.6632473 7.474743e-05 8.265040e-06 2.898353e-04 11 64219524 64219658 135 + 2.503 2.423 -0.264
ENSG00000149781 E057 4.2184128 4.458933e-03 6.817114e-03 6.199860e-02 11 64219659 64219739 81 + 0.531 0.865 1.401
ENSG00000149781 E058 117.1734385 1.578976e-04 8.039442e-03 6.935368e-02 11 64219740 64219744 5 + 2.104 2.029 -0.252
ENSG00000149781 E059 168.9768846 1.304921e-04 1.575391e-02 1.086615e-01 11 64219745 64219789 45 + 2.254 2.197 -0.191
ENSG00000149781 E060 7.7194769 6.035005e-03 4.332192e-06 1.664090e-04 11 64219790 64219878 89 + 0.652 1.135 1.860
ENSG00000149781 E061 8.7055955 2.310854e-03 6.067518e-06 2.218614e-04 11 64219879 64219890 12 + 0.729 1.169 1.658
ENSG00000149781 E062 277.2498273 7.566022e-05 4.470565e-02 2.067353e-01 11 64219891 64220015 125 + 2.460 2.423 -0.122
ENSG00000149781 E063 225.9997124 8.100723e-04 2.926431e-01 5.861775e-01 11 64220220 64220326 107 + 2.366 2.341 -0.082
ENSG00000149781 E064 10.6657605 5.062353e-03 3.578416e-05 1.002068e-03 11 64220327 64220407 81 + 0.851 1.229 1.387
ENSG00000149781 E065 13.0230996 3.434885e-03 3.458378e-06 1.363481e-04 11 64220408 64220435 28 + 0.925 1.312 1.399
ENSG00000149781 E066 107.3517438 2.582366e-03 2.778896e-01 5.711775e-01 11 64220436 64220441 6 + 2.015 2.054 0.130
ENSG00000149781 E067 395.3339387 1.459017e-04 1.463612e-01 4.073788e-01 11 64220442 64220669 228 + 2.586 2.609 0.075
ENSG00000149781 E068 12.2195246 1.301477e-03 6.053139e-04 1.013567e-02 11 64220670 64220741 72 + 0.967 1.250 1.019
ENSG00000149781 E069 23.4621220 1.269406e-03 2.848496e-06 1.151655e-04 11 64220742 64221015 274 + 1.228 1.521 1.017
ENSG00000149781 E070 305.7192326 3.224136e-04 2.103387e-01 4.947841e-01 11 64221016 64221140 125 + 2.475 2.498 0.077
ENSG00000149781 E071 61.6502478 2.488962e-04 7.799905e-26 3.375703e-23 11 64221141 64223047 1907 + 1.555 1.972 1.411
ENSG00000149781 E072 388.0957486 4.837526e-04 3.677422e-02 1.846036e-01 11 64223048 64223189 142 + 2.572 2.608 0.120
ENSG00000149781 E073 936.7913069 4.576768e-05 7.136968e-06 2.550863e-04 11 64223313 64223896 584 + 2.951 2.993 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.