ENSG00000150403

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000434316 ENSG00000150403 No_inf pgKDN_inf TMCO3 protein_coding protein_coding 32.95495 20.12412 43.59262 0.8281088 4.598839 1.114773 20.069560 12.5482709 23.066194 0.6033980 1.1552770 0.8777675 0.62427500 0.629250 0.547375 -0.081875 8.243288e-01 4.051996e-09 FALSE TRUE
ENST00000465556 ENSG00000150403 No_inf pgKDN_inf TMCO3 protein_coding protein_coding_CDS_not_defined 32.95495 20.12412 43.59262 0.8281088 4.598839 1.114773 3.292504 0.0000000 7.766519 0.0000000 3.1677794 9.6029807 0.07320000 0.000000 0.161550 0.161550 2.620856e-02 4.051996e-09   FALSE
ENST00000474393 ENSG00000150403 No_inf pgKDN_inf TMCO3 protein_coding protein_coding 32.95495 20.12412 43.59262 0.8281088 4.598839 1.114773 1.860089 1.2738081 1.804531 0.2807114 0.3473441 0.4991674 0.05895000 0.064050 0.041825 -0.022225 8.335944e-01 4.051996e-09 FALSE TRUE
ENST00000491166 ENSG00000150403 No_inf pgKDN_inf TMCO3 protein_coding protein_coding_CDS_not_defined 32.95495 20.12412 43.59262 0.8281088 4.598839 1.114773 1.429893 3.8079011 0.000000 0.7484404 0.0000000 -8.5766359 0.06734167 0.188350 0.000000 -0.188350 4.051996e-09 4.051996e-09   FALSE
MSTRG.8100.1 ENSG00000150403 No_inf pgKDN_inf TMCO3 protein_coding   32.95495 20.12412 43.59262 0.8281088 4.598839 1.114773 4.051751 0.8278805 6.838023 0.3380526 1.5810856 3.0308712 0.11250000 0.039575 0.164300 0.124725 2.414958e-01 4.051996e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000150403 E001 0.4686426 0.1721984417 0.1961701246   13 113491019 113491020 2 + 0.239 0.000 -10.189
ENSG00000150403 E002 1.3108200 0.0122236402 0.1992551414 0.480897964 13 113491021 113491042 22 + 0.424 0.218 -1.348
ENSG00000150403 E003 4.2131952 0.0430805153 0.4417206001 0.717194257 13 113491043 113491095 53 + 0.748 0.629 -0.500
ENSG00000150403 E004 14.6070135 0.0019224230 0.2886277642 0.582177712 13 113491096 113491273 178 + 1.212 1.126 -0.305
ENSG00000150403 E005 38.9823411 0.0004101298 0.0001130137 0.002625013 13 113495502 113495870 369 + 1.653 1.457 -0.670
ENSG00000150403 E006 24.6594306 0.0013185397 0.3230872421 0.615846874 13 113495871 113496025 155 + 1.374 1.432 0.201
ENSG00000150403 E007 25.6310724 0.0112897647 0.4450911658 0.719532500 13 113498342 113498521 180 + 1.434 1.376 -0.199
ENSG00000150403 E008 0.3543453 0.0163005912 0.2703233156   13 113498522 113498645 124 + 0.191 0.000 -11.926
ENSG00000150403 E009 15.6571665 0.0118562117 0.0777404160 0.285325049 13 113499958 113500020 63 + 1.263 1.104 -0.563
ENSG00000150403 E010 10.6187315 0.0013816987 0.2903773153 0.584024841 13 113500021 113500023 3 + 1.087 0.991 -0.354
ENSG00000150403 E011 25.0978333 0.0005821631 0.0762847808 0.282299381 13 113500024 113500149 126 + 1.442 1.332 -0.381
ENSG00000150403 E012 27.2800774 0.0006333470 0.1042623556 0.337444757 13 113501752 113501880 129 + 1.473 1.376 -0.334
ENSG00000150403 E013 19.3056870 0.0007881799 0.4384448990 0.714638667 13 113503496 113503588 93 + 1.275 1.326 0.176
ENSG00000150403 E014 4.5719056 0.0031848944 0.0014211917 0.019626934 13 113503589 113506062 2474 + 0.554 0.929 1.538
ENSG00000150403 E015 29.7306742 0.0005139939 0.7170929590 0.886081645 13 113510238 113510424 187 + 1.468 1.486 0.063
ENSG00000150403 E016 0.0000000       13 113520546 113520615 70 +      
ENSG00000150403 E017 23.5328573 0.0009410077 0.9923473668 1.000000000 13 113520616 113520733 118 + 1.377 1.376 -0.003
ENSG00000150403 E018 40.6407465 0.0003907764 0.6205976998 0.835967840 13 113534045 113534240 196 + 1.598 1.620 0.073
ENSG00000150403 E019 6.8188511 0.0068744345 0.3112616171 0.604456993 13 113534241 113535286 1046 + 0.838 0.945 0.407
ENSG00000150403 E020 30.5572517 0.0006356715 0.8768454991 0.958242496 13 113539357 113539507 151 + 1.484 1.490 0.023
ENSG00000150403 E021 0.2448930 0.0161169343 0.6552856453   13 113545755 113545897 143 + 0.073 0.122 0.822
ENSG00000150403 E022 0.3726284 0.0167993904 0.2896574670   13 113547149 113547299 151 + 0.073 0.218 1.822
ENSG00000150403 E023 15.6038503 0.0008734906 0.0723402090 0.272859715 13 113547300 113547379 80 + 1.154 1.284 0.459
ENSG00000150403 E024 11.7050141 0.0012095591 0.1213786485 0.368779015 13 113548303 113548332 30 + 1.039 1.166 0.459
ENSG00000150403 E025 25.5151513 0.0005652676 0.2908227995 0.584354253 13 113548333 113548452 120 + 1.387 1.447 0.208
ENSG00000150403 E026 19.0163325 0.0008680520 0.7905748692 0.919694254 13 113549425 113549501 77 + 1.296 1.276 -0.069
ENSG00000150403 E027 29.2282741 0.0091231891 0.9324194235 0.980351857 13 113549502 113549633 132 + 1.470 1.462 -0.028
ENSG00000150403 E028 70.4126554 0.0003200574 0.0344779720 0.177318103 13 113549634 113550229 596 + 1.812 1.884 0.241
ENSG00000150403 E029 0.0000000       13 113550755 113550815 61 +      
ENSG00000150403 E030 0.0000000       13 113551337 113551428 92 +      
ENSG00000150403 E031 0.1265070 0.0122112799 0.2932105129   13 113551429 113551562 134 + 0.000 0.122 11.445
ENSG00000150403 E032 0.2442663 0.0160692462 0.6553259104   13 113551563 113552031 469 + 0.073 0.122 0.822
ENSG00000150403 E033 3.3542656 0.0042728736 0.0003390286 0.006424865 13 113552032 113554590 2559 + 0.393 0.856 2.070

Help

Please Click HERE to learn more details about the results from DEXseq.