ENSG00000150471

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000502815 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding protein_coding 9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 0.7274854 1.4836841 0.0000000 0.8998936 0.0000000 -7.2227313 0.15570000 0.278025 0.000000 -0.278025 0.807802281 0.007668988 FALSE TRUE
ENST00000509779 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding protein_coding_CDS_not_defined 9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 0.2688877 0.6275036 0.1791594 0.4425711 0.1791594 -1.7528311 0.04718333 0.100075 0.041475 -0.058600 0.925751275 0.007668988   FALSE
ENST00000512091 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding protein_coding 9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 0.4935160 0.7514568 0.3232921 0.2836815 0.2043438 -1.1919752 0.10060000 0.128175 0.091100 -0.037075 0.897760297 0.007668988 FALSE TRUE
ENST00000683033 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding protein_coding 9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 0.6415019 0.8329966 0.6988414 0.1916508 0.2151578 -0.2500639 0.11057500 0.092100 0.148250 0.056150 0.770435755 0.007668988 FALSE TRUE
MSTRG.21842.17 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding   9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 5.0417562 15.1252686 0.0000000 15.1252686 0.0000000 -10.5636986 0.07690000 0.230700 0.000000 -0.230700 0.964636992 0.007668988   FALSE
MSTRG.21842.19 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding   9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 1.3887692 1.8382579 1.6262714 0.7865744 0.0917606 -0.1757540 0.23579167 0.169975 0.405700 0.235725 0.460822997 0.007668988 FALSE TRUE
MSTRG.21842.21 ENSG00000150471 No_inf pgKDN_inf ADGRL3 protein_coding   9.923416 20.71987 4.486587 14.95055 0.6953268 -2.204809 0.9148366 0.0000000 1.5377691 0.0000000 0.6303838 7.2740465 0.17678333 0.000000 0.292975 0.292975 0.007668988 0.007668988 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000150471 E001 3.1832142 0.0046385779 0.1662072355 0.436406263 4 61200326 61201257 932 + 0.715 0.533 -0.797
ENSG00000150471 E002 4.3216868 0.0633236515 0.6731660372 0.864626635 4 61201258 61201663 406 + 0.742 0.690 -0.212
ENSG00000150471 E003 2.3568388 0.0093888715 0.6572096253 0.856614103 4 61201664 61201765 102 + 0.468 0.533 0.319
ENSG00000150471 E004 0.1271363 0.0122987558 1.0000000000   4 61202142 61202231 90 + 0.000 0.074 9.720
ENSG00000150471 E005 1.5059997 0.0098495538 0.1326343235 0.386571176 4 61383124 61383189 66 + 0.216 0.456 1.525
ENSG00000150471 E006 0.6265274 0.2025396983 0.5203445294 0.774707612 4 61385411 61385769 359 + 0.121 0.241 1.203
ENSG00000150471 E007 0.8708850 0.0131689763 0.6595846308 0.857949968 4 61497121 61497164 44 + 0.216 0.285 0.525
ENSG00000150471 E008 0.6072630 0.0147574879 0.2917246217 0.585124236 4 61497165 61497187 23 + 0.294 0.137 -1.382
ENSG00000150471 E009 0.7252719 0.0142152729 0.1387288334 0.396072251 4 61497188 61497198 11 + 0.360 0.137 -1.797
ENSG00000150471 E010 1.2251016 0.0103458269 0.3900344270 0.675517908 4 61497199 61497293 95 + 0.417 0.285 -0.797
ENSG00000150471 E011 1.1345048 0.0107829808 0.0874822186 0.306560066 4 61497294 61497348 55 + 0.121 0.395 2.203
ENSG00000150471 E012 0.7437465 0.0140858850 0.8695588581 0.955134144 4 61517315 61517518 204 + 0.216 0.241 0.203
ENSG00000150471 E013 0.9793882 0.0123533119 0.4433259102 0.718259342 4 61587227 61587276 50 + 0.360 0.241 -0.797
ENSG00000150471 E014 1.8509649 0.0074832089 0.7851763903 0.917174189 4 61587277 61587367 91 + 0.468 0.427 -0.212
ENSG00000150471 E015 1.7430283 0.0086700740 0.5315879864 0.782187071 4 61587368 61587440 73 + 0.360 0.456 0.525
ENSG00000150471 E016 0.1271363 0.0122987558 1.0000000000   4 61590638 61590669 32 + 0.000 0.074 9.720
ENSG00000150471 E017 1.3614585 0.0202064085 0.9859548229 0.999194425 4 61676826 61676920 95 + 0.360 0.362 0.011
ENSG00000150471 E018 0.8618152 0.4704210148 0.9175121192 0.974066581 4 61676921 61676935 15 + 0.294 0.241 -0.380
ENSG00000150471 E019 0.0000000       4 61676936 61677392 457 +      
ENSG00000150471 E020 0.7441846 0.3187128521 0.8925513952 0.964339569 4 61730622 61730636 15 + 0.216 0.241 0.205
ENSG00000150471 E021 10.1041200 0.0019675288 0.3586041938 0.648158193 4 61732754 61733554 801 + 1.078 0.996 -0.299
ENSG00000150471 E022 2.8673394 0.0064412458 0.2911027566 0.584655399 4 61813809 61813889 81 + 0.468 0.619 0.706
ENSG00000150471 E023 8.7424154 0.0018164748 0.3217575381 0.614795340 4 61892656 61892958 303 + 1.028 0.935 -0.346
ENSG00000150471 E024 2.0669111 0.0074135720 0.0651333855 0.257028370 4 61895731 61895740 10 + 0.626 0.362 -1.311
ENSG00000150471 E025 4.2698932 0.0035512249 0.0339733411 0.175526217 4 61895741 61895834 94 + 0.853 0.599 -1.045
ENSG00000150471 E026 5.7958412 0.0023462412 0.5837867050 0.814892984 4 61909560 61909745 186 + 0.853 0.792 -0.237
ENSG00000150471 E027 0.4979097 0.0157533363 0.6549556174   4 61912719 61912757 39 + 0.121 0.192 0.788
ENSG00000150471 E028 0.1265070 0.0123024411 1.0000000000   4 61933843 61933958 116 + 0.000 0.074 9.720
ENSG00000150471 E029 6.2785459 0.0021695883 0.3343212676 0.626169117 4 61934840 61935023 184 + 0.908 0.805 -0.398
ENSG00000150471 E030 6.4686447 0.0157681538 0.0133364190 0.096912749 4 61935923 61936045 123 + 1.015 0.737 -1.070
ENSG00000150471 E031 5.9618485 0.0213444339 0.4941404895 0.755734387 4 61946914 61947122 209 + 0.766 0.853 0.341
ENSG00000150471 E032 1.2266751 0.0515235718 0.4172787091 0.697031787 4 61948100 61948102 3 + 0.417 0.285 -0.797
ENSG00000150471 E033 5.5232705 0.0060775515 0.1770056309 0.451401831 4 61948103 61948276 174 + 0.891 0.737 -0.604
ENSG00000150471 E034 6.5279743 0.0107637093 0.4770926840 0.743492063 4 61979563 61979772 210 + 0.908 0.830 -0.302
ENSG00000150471 E035 9.2812353 0.0108605063 0.9492434166 0.986763833 4 61983383 61983603 221 + 0.987 0.996 0.033
ENSG00000150471 E036 4.4394107 0.0034134181 0.5295514641 0.780905251 4 61996291 61996357 67 + 0.766 0.690 -0.311
ENSG00000150471 E037 3.7019541 0.0041539269 0.7018723236 0.878688561 4 61998174 61998265 92 + 0.688 0.638 -0.212
ENSG00000150471 E038 0.0000000       4 62028855 62028881 27 +      
ENSG00000150471 E039 6.3003774 0.0155016566 0.7234624706 0.888932815 4 62031442 62031610 169 + 0.872 0.830 -0.165
ENSG00000150471 E040 5.0681145 0.0027272133 0.9954753575 1.000000000 4 62037731 62037856 126 + 0.766 0.766 -0.003
ENSG00000150471 E041 4.6851929 0.0031635572 0.7108544452 0.883105971 4 62044453 62044549 97 + 0.766 0.722 -0.180
ENSG00000150471 E042 0.1176306 0.0116168643 0.2999193561   4 62063505 62063633 129 + 0.121 0.000 -11.718
ENSG00000150471 E043 0.0000000       4 62068166 62068183 18 +      
ENSG00000150471 E044 0.0000000       4 62068184 62068217 34 +      
ENSG00000150471 E045 158.0569091 0.0002431555 0.0002189122 0.004504697 4 62070109 62078335 8227 + 2.138 2.202 0.213

Help

Please Click HERE to learn more details about the results from DEXseq.