ENSG00000150753

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000280326 ENSG00000150753 No_inf pgKDN_inf CCT5 protein_coding protein_coding 149.827 78.01065 189.2244 6.533524 4.656735 1.278246 63.15041 35.813676 81.03194 0.947243 1.818304 1.177755 0.4319333 0.467300 0.429300 -0.0380 0.83537059 0.03642977 FALSE  
ENST00000511700 ENSG00000150753 No_inf pgKDN_inf CCT5 protein_coding nonsense_mediated_decay 149.827 78.01065 189.2244 6.533524 4.656735 1.278246 17.83478 3.956342 22.80809 3.956342 3.086806 2.524297 0.1029417 0.042475 0.119575 0.0771 0.03642977 0.03642977 FALSE  
ENST00000512975 ENSG00000150753 No_inf pgKDN_inf CCT5 protein_coding nonsense_mediated_decay 149.827 78.01065 189.2244 6.533524 4.656735 1.278246 57.98397 25.747137 76.23001 4.424946 2.704433 1.565576 0.3729333 0.322225 0.402625 0.0804 0.49360413 0.03642977 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000150753 E001 0.1271363 0.0122472867 0.249892530   5 10249929 10250045 117 + 0.000 0.130 11.922
ENSG00000150753 E002 0.0000000       5 10250216 10250242 27 +      
ENSG00000150753 E003 1.0824840 0.0124215497 0.482950331 0.74767332 5 10250243 10250279 37 + 0.343 0.230 -0.782
ENSG00000150753 E004 7.0990335 0.0020837943 0.211150663 0.49600174 5 10250280 10250308 29 + 0.932 0.795 -0.527
ENSG00000150753 E005 12.4458916 0.0176453972 0.687740253 0.87125553 5 10250309 10250318 10 + 1.120 1.086 -0.124
ENSG00000150753 E006 29.7873883 0.0104649875 0.330714021 0.62315252 5 10250319 10250340 22 + 1.489 1.423 -0.227
ENSG00000150753 E007 33.9116675 0.0109800626 0.420982808 0.70015377 5 10250341 10250359 19 + 1.539 1.487 -0.180
ENSG00000150753 E008 57.3980439 0.0011916658 0.528858042 0.78032139 5 10250360 10250445 86 + 1.754 1.727 -0.090
ENSG00000150753 E009 0.0000000       5 10250537 10250538 2 +      
ENSG00000150753 E010 0.4992916 0.0358643974 0.092892091   5 10250539 10250893 355 + 0.069 0.311 2.611
ENSG00000150753 E011 44.9149270 0.0004622288 0.768041213 0.91023462 5 10254145 10254205 61 + 1.635 1.650 0.049
ENSG00000150753 E012 1.6248284 0.0084847303 0.001341747 0.01878168 5 10254206 10254584 379 + 0.180 0.652 2.763
ENSG00000150753 E013 74.0988414 0.0002170086 0.655191409 0.85537116 5 10254674 10254765 92 + 1.860 1.844 -0.053
ENSG00000150753 E014 49.3676473 0.0004089058 0.208080565 0.49180819 5 10254766 10254795 30 + 1.700 1.643 -0.192
ENSG00000150753 E015 56.8111619 0.0002537384 0.103398770 0.33614884 5 10254796 10254838 43 + 1.763 1.695 -0.230
ENSG00000150753 E016 0.6328821 0.3425266534 0.018095700 0.11867382 5 10254839 10255030 192 + 0.000 0.438 14.247
ENSG00000150753 E017 120.7880254 0.0001386285 0.242658397 0.53229503 5 10255955 10256153 199 + 2.075 2.043 -0.108
ENSG00000150753 E018 0.1186381 0.0118077563 1.000000000   5 10257886 10258110 225 + 0.069 0.000 -9.981
ENSG00000150753 E019 129.4161060 0.0001459827 0.776097618 0.91403797 5 10258111 10258303 193 + 2.091 2.099 0.028
ENSG00000150753 E020 144.0981214 0.0001129058 0.650582915 0.85292969 5 10258386 10258535 150 + 2.144 2.133 -0.037
ENSG00000150753 E021 119.7584626 0.0001667636 0.541864203 0.78935784 5 10260792 10260911 120 + 2.066 2.049 -0.056
ENSG00000150753 E022 2.3416050 0.0065447444 0.028141355 0.15682743 5 10260912 10261187 276 + 0.375 0.685 1.485
ENSG00000150753 E023 161.1615619 0.0001321968 0.829682204 0.93827225 5 10261560 10261745 186 + 2.190 2.185 -0.015
ENSG00000150753 E024 3.5608805 0.0868520504 0.099949814 0.33035257 5 10261746 10261974 229 + 0.532 0.795 1.124
ENSG00000150753 E025 6.3371356 0.0026162034 0.096055875 0.32278365 5 10261975 10262480 506 + 0.776 0.956 0.691
ENSG00000150753 E026 139.0721702 0.0001647199 0.085885851 0.30342778 5 10262481 10262618 138 + 2.109 2.154 0.150
ENSG00000150753 E027 129.5289229 0.0004730344 0.011628309 0.08877017 5 10263134 10263314 181 + 2.069 2.138 0.234
ENSG00000150753 E028 0.0000000       5 10264656 10266389 1734 +      

Help

Please Click HERE to learn more details about the results from DEXseq.