ENSG00000150990

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308736 ENSG00000150990 No_inf pgKDN_inf DHX37 protein_coding protein_coding 11.96454 5.988638 14.30212 0.3217757 0.2854755 1.254531 10.6564241 4.9221820 13.97156 0.10915645 0.2604812 1.503227 0.886175 0.82815 0.977075 0.148925 0.012159281 0.009916168 FALSE TRUE
ENST00000507267 ENSG00000150990 No_inf pgKDN_inf DHX37 protein_coding retained_intron 11.96454 5.988638 14.30212 0.3217757 0.2854755 1.254531 0.3197392 0.5652897 0.00000 0.08643814 0.0000000 -5.846217 0.038225 0.09300 0.000000 -0.093000 0.009916168 0.009916168 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000150990 E001 0.6164191 0.0157020593 0.1603443662 0.42807474 12 124946825 124946825 1 - 0.119 0.330 1.844
ENSG00000150990 E002 0.8526879 0.0668782042 0.4772541924 0.74357188 12 124946826 124946830 5 - 0.213 0.330 0.844
ENSG00000150990 E003 41.2199136 0.0003556957 0.2218078421 0.50904149 12 124946831 124947600 770 - 1.575 1.630 0.188
ENSG00000150990 E004 21.8258538 0.0065554789 0.8660755906 0.95384862 12 124947601 124947887 287 - 1.331 1.316 -0.052
ENSG00000150990 E005 0.0000000       12 124947888 124948083 196 -      
ENSG00000150990 E006 9.2178040 0.0018131963 0.1630476343 0.43170403 12 124948084 124948181 98 - 0.934 1.065 0.481
ENSG00000150990 E007 0.3723465 0.0165291447 0.1845902301   12 124948182 124948615 434 - 0.064 0.245 2.259
ENSG00000150990 E008 8.5772875 0.0018401270 0.7686666623 0.91054272 12 124949986 124950059 74 - 0.942 0.970 0.104
ENSG00000150990 E009 10.8705547 0.0015275745 0.7199252419 0.88710185 12 124950149 124950243 95 - 1.034 1.065 0.112
ENSG00000150990 E010 13.5881210 0.0010841591 0.0630632371 0.25263014 12 124950413 124950550 138 - 1.082 1.228 0.522
ENSG00000150990 E011 0.4815440 0.0224607843 0.9337225468   12 124950551 124950689 139 - 0.169 0.139 -0.326
ENSG00000150990 E012 16.0059038 0.0009596475 0.0808136917 0.29219256 12 124950690 124950804 115 - 1.155 1.283 0.452
ENSG00000150990 E013 17.4584563 0.0008644750 0.1128764862 0.35345334 12 124952398 124952570 173 - 1.196 1.308 0.392
ENSG00000150990 E014 0.8603046 0.2487774747 0.1778723748 0.45264066 12 124952571 124953740 1170 - 0.169 0.400 1.674
ENSG00000150990 E015 11.2507637 0.0012755622 0.4072462937 0.68975071 12 124953880 124953996 117 - 1.034 1.105 0.259
ENSG00000150990 E016 9.9048927 0.0079268145 0.6700904082 0.86299349 12 124954087 124954211 125 - 0.994 1.035 0.152
ENSG00000150990 E017 0.4833068 0.0193181588 0.9338983969   12 124956410 124956690 281 - 0.169 0.139 -0.326
ENSG00000150990 E018 11.9484052 0.0202309611 0.9899741718 1.00000000 12 124956691 124956879 189 - 1.082 1.078 -0.013
ENSG00000150990 E019 9.0244447 0.0059818184 0.6138237807 0.83210104 12 124957029 124957135 107 - 0.987 0.933 -0.201
ENSG00000150990 E020 8.1516936 0.0020230586 0.1721969584 0.44484103 12 124960312 124960423 112 - 0.972 0.825 -0.562
ENSG00000150990 E021 0.0000000       12 124964393 124964393 1 -      
ENSG00000150990 E022 16.1139141 0.0235442731 0.3809835616 0.66740425 12 124964394 124964626 233 - 1.226 1.142 -0.297
ENSG00000150990 E023 5.9666503 0.0068998280 0.0121031264 0.09105454 12 124964930 124965006 77 - 0.892 0.562 -1.360
ENSG00000150990 E024 10.4798472 0.0077890725 0.5654200484 0.80430871 12 124965668 124965812 145 - 1.046 0.987 -0.218
ENSG00000150990 E025 7.3915849 0.0026377171 0.3965623022 0.68123985 12 124966793 124966878 86 - 0.865 0.952 0.329
ENSG00000150990 E026 0.1272623 0.0124337593 0.2030092093   12 124966879 124967005 127 - 0.000 0.139 10.474
ENSG00000150990 E027 8.0402711 0.0107047103 0.0335778068 0.17432177 12 124967123 124967218 96 - 0.846 1.065 0.818
ENSG00000150990 E028 7.7446369 0.0021508153 0.3900397389 0.67551791 12 124968534 124968648 115 - 0.883 0.970 0.326
ENSG00000150990 E029 6.3256369 0.0282165863 0.0620478524 0.25022192 12 124968867 124968968 102 - 0.901 0.644 -1.030
ENSG00000150990 E030 8.5379929 0.0018436828 0.4474664477 0.72161390 12 124971302 124971415 114 - 0.972 0.893 -0.299
ENSG00000150990 E031 6.9745244 0.0414638061 0.6511462572 0.85304288 12 124972503 124972599 97 - 0.892 0.825 -0.260
ENSG00000150990 E032 4.0563864 0.0067011796 0.0477295238 0.21486054 12 124975419 124975511 93 - 0.747 0.461 -1.277
ENSG00000150990 E033 5.5076311 0.0025077007 0.1289372251 0.38094222 12 124977342 124977490 149 - 0.836 0.644 -0.781
ENSG00000150990 E034 12.5261708 0.0011735973 0.0006317194 0.01044807 12 124980490 124980838 349 - 1.178 0.849 -1.217
ENSG00000150990 E035 6.6966303 0.0021483096 0.0469871894 0.21294068 12 124982511 124982623 113 - 0.918 0.680 -0.943
ENSG00000150990 E036 6.1086256 0.0024522141 0.1111189328 0.34997568 12 124986096 124986265 170 - 0.874 0.680 -0.777
ENSG00000150990 E037 6.1495119 0.0046954743 0.9966675966 1.00000000 12 124988917 124989131 215 - 0.826 0.825 -0.004

Help

Please Click HERE to learn more details about the results from DEXseq.