ENSG00000151611

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000506919 ENSG00000151611 No_inf pgKDN_inf MMAA protein_coding retained_intron 1.781599 1.303516 2.228729 0.1102698 0.07030457 0.7692456 0.49153174 0.00000000 0.9106861 0.00000000 0.1112981 6.5246375 0.21409167 0.00000 0.409875 0.409875 0.02902834 0.02902834 FALSE TRUE
ENST00000647947 ENSG00000151611 No_inf pgKDN_inf MMAA protein_coding nonsense_mediated_decay 1.781599 1.303516 2.228729 0.1102698 0.07030457 0.7692456 0.06243616 0.05432789 0.0000000 0.05432789 0.0000000 -2.6854443 0.04504167 0.05245 0.000000 -0.052450 0.80780228 0.02902834 FALSE TRUE
ENST00000648388 ENSG00000151611 No_inf pgKDN_inf MMAA protein_coding protein_coding 1.781599 1.303516 2.228729 0.1102698 0.07030457 0.7692456 0.59074981 0.35791980 0.5783722 0.35791980 0.3431812 0.6773378 0.33524167 0.25000 0.274125 0.024125 0.89365062 0.02902834 FALSE TRUE
ENST00000649156 ENSG00000151611 No_inf pgKDN_inf MMAA protein_coding protein_coding 1.781599 1.303516 2.228729 0.1102698 0.07030457 0.7692456 0.50950983 0.50915357 0.7396707 0.30504607 0.4297788 0.5300957 0.32229167 0.44755 0.316000 -0.131550 0.94824042 0.02902834 FALSE TRUE
ENST00000679930 ENSG00000151611 No_inf pgKDN_inf MMAA protein_coding nonsense_mediated_decay 1.781599 1.303516 2.228729 0.1102698 0.07030457 0.7692456 0.10989591 0.32968774 0.0000000 0.32968774 0.0000000 -5.0861373 0.07190000 0.21570 0.000000 -0.215700 0.82720950 0.02902834 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151611 E001 0.0000000       4 145599042 145599060 19 +      
ENSG00000151611 E002 0.0000000       4 145599061 145599067 7 +      
ENSG00000151611 E003 0.0000000       4 145599068 145599082 15 +      
ENSG00000151611 E004 0.0000000       4 145599083 145599108 26 +      
ENSG00000151611 E005 0.0000000       4 145599109 145599304 196 +      
ENSG00000151611 E006 0.0000000       4 145599305 145599354 50 +      
ENSG00000151611 E007 0.0000000       4 145600396 145600853 458 +      
ENSG00000151611 E008 0.1271363 0.012599065 4.782198e-01   4 145618985 145619384 400 + 0.000 0.100 9.125
ENSG00000151611 E009 0.7188838 0.015268172 1.250750e-01 0.374914326 4 145619385 145619407 23 + 0.333 0.100 -2.149
ENSG00000151611 E010 0.1187032 0.012199472 6.027712e-01   4 145619504 145619649 146 + 0.090 0.000 -11.850
ENSG00000151611 E011 0.0000000       4 145625992 145626208 217 +      
ENSG00000151611 E012 0.7188838 0.015268172 1.250750e-01 0.374914326 4 145639075 145639079 5 + 0.333 0.100 -2.149
ENSG00000151611 E013 1.2086422 0.013054943 2.838489e-01 0.577527726 4 145639080 145639092 13 + 0.417 0.250 -1.050
ENSG00000151611 E014 1.3262729 0.011200544 1.861334e-01 0.463995337 4 145639093 145639098 6 + 0.454 0.250 -1.242
ENSG00000151611 E015 7.5200388 0.002087817 9.673514e-02 0.323895770 4 145639099 145639574 476 + 1.000 0.844 -0.589
ENSG00000151611 E016 0.0000000       4 145639575 145639578 4 +      
ENSG00000151611 E017 0.1272623 0.012850420 4.778592e-01   4 145639579 145639866 288 + 0.000 0.100 11.045
ENSG00000151611 E018 0.0000000       4 145642363 145642485 123 +      
ENSG00000151611 E019 2.4084757 0.021310436 1.315531e-01 0.384771392 4 145645986 145646156 171 + 0.626 0.408 -1.049
ENSG00000151611 E020 0.0000000       4 145646157 145646622 466 +      
ENSG00000151611 E021 0.2357071 0.016196347 2.855832e-01   4 145650919 145651061 143 + 0.165 0.000 -12.695
ENSG00000151611 E022 2.6642524 0.007453788 3.166775e-01 0.609534013 4 145651062 145651127 66 + 0.626 0.488 -0.635
ENSG00000151611 E023 2.6672126 0.005777162 3.128978e-01 0.606298199 4 145651128 145651147 20 + 0.626 0.488 -0.635
ENSG00000151611 E024 6.8450589 0.002262953 8.312765e-01 0.939070971 4 145653994 145654143 150 + 0.886 0.904 0.070
ENSG00000151611 E025 23.9043336 0.001255412 4.043761e-05 0.001110469 4 145655147 145660033 4887 + 1.299 1.479 0.622

Help

Please Click HERE to learn more details about the results from DEXseq.