ENSG00000151665

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000281382 ENSG00000151665 No_inf pgKDN_inf PIGF protein_coding protein_coding 24.22953 19.71514 28.12744 0.8161092 1.412214 0.5124557 17.782180 11.552115 22.2293324 0.6224706 1.2935638 0.9437082 0.72400833 0.588200 0.7899 0.201700 0.03716535 0.03716535 FALSE TRUE
ENST00000306465 ENSG00000151665 No_inf pgKDN_inf PIGF protein_coding protein_coding 24.22953 19.71514 28.12744 0.8161092 1.412214 0.5124557 1.443118 1.507067 0.6765958 0.9352477 0.6765958 -1.1437516 0.06000833 0.074625 0.0222 -0.052425 0.78985637 0.03716535 FALSE TRUE
ENST00000482786 ENSG00000151665 No_inf pgKDN_inf PIGF protein_coding protein_coding_CDS_not_defined 24.22953 19.71514 28.12744 0.8161092 1.412214 0.5124557 2.529906 3.952551 2.0946027 0.4724828 0.6453960 -0.9128815 0.11388333 0.202350 0.0772 -0.125150 0.27073655 0.03716535   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151665 E001 0.0000000       2 46580937 46581284 348 -      
ENSG00000151665 E002 0.0000000       2 46581285 46581415 131 -      
ENSG00000151665 E003 0.0000000       2 46581416 46581591 176 -      
ENSG00000151665 E004 1.9328261 0.151486979 0.3426028066 0.63402517 2 46588075 46588126 52 - 0.547 0.363 -0.951
ENSG00000151665 E005 2.3213820 0.208962240 0.8709679225 0.95561692 2 46588127 46588179 53 - 0.518 0.525 0.035
ENSG00000151665 E006 5.8466722 0.019038079 0.0008254648 0.01292106 2 46588180 46588622 443 - 0.600 0.995 1.573
ENSG00000151665 E007 2.8297231 0.006096282 0.3568574638 0.64666702 2 46591803 46591925 123 - 0.518 0.643 0.564
ENSG00000151665 E008 8.9601889 0.002830065 0.3626933946 0.65192034 2 46592475 46592583 109 - 0.956 1.038 0.305
ENSG00000151665 E009 15.2571514 0.001045424 0.5877088004 0.81702976 2 46612228 46612344 117 - 1.226 1.194 -0.115
ENSG00000151665 E010 11.0458833 0.001550042 0.0799418724 0.29020562 2 46613694 46613785 92 - 1.141 1.006 -0.492
ENSG00000151665 E011 0.0000000       2 46613786 46614936 1151 -      
ENSG00000151665 E012 12.1755879 0.001356664 0.3881689974 0.67401264 2 46614937 46615017 81 - 1.149 1.087 -0.221
ENSG00000151665 E013 11.5932973 0.001421587 0.5633890536 0.80272904 2 46615018 46615185 168 - 1.119 1.078 -0.150
ENSG00000151665 E014 0.6258013 0.077127901 0.1488578895 0.41094199 2 46615186 46616586 1401 - 0.090 0.311 2.186
ENSG00000151665 E015 0.0000000       2 46616587 46616969 383 -      
ENSG00000151665 E016 0.0000000       2 46616970 46617055 86 -      

Help

Please Click HERE to learn more details about the results from DEXseq.