ENSG00000151694

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310823 ENSG00000151694 No_inf pgKDN_inf ADAM17 protein_coding protein_coding 81.69625 76.92541 93.06251 1.32235 0.7512216 0.2747074 66.408873 57.257528 79.850378 1.2408368 1.1671683 0.4797626 0.81083333 0.7448 0.858125 0.113325 0.009019697 0.009019697 FALSE TRUE
ENST00000699320 ENSG00000151694 No_inf pgKDN_inf ADAM17 protein_coding retained_intron 81.69625 76.92541 93.06251 1.32235 0.7512216 0.2747074 5.183056 7.828676 2.880037 0.7017553 0.6610423 -1.4395221 0.06541667 0.1016 0.030800 -0.070800 0.069383664 0.009019697 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151694 E001 0.0000000       2 9488486 9488636 151 -      
ENSG00000151694 E002 0.0000000       2 9488637 9489267 631 -      
ENSG00000151694 E003 0.0000000       2 9489268 9489287 20 -      
ENSG00000151694 E004 0.0000000       2 9489288 9489305 18 -      
ENSG00000151694 E005 0.0000000       2 9489306 9489394 89 -      
ENSG00000151694 E006 0.0000000       2 9489395 9489588 194 -      
ENSG00000151694 E007 2.9284175 6.439385e-03 9.776052e-01 9.966572e-01 2 9489589 9489751 163 - 0.596 0.592 -0.016
ENSG00000151694 E008 23.9623119 6.147930e-04 7.134754e-01 8.845150e-01 2 9489752 9489779 28 - 1.386 1.408 0.077
ENSG00000151694 E009 47.3236067 3.266826e-04 5.773227e-01 8.111200e-01 2 9489780 9489810 31 - 1.672 1.696 0.083
ENSG00000151694 E010 78.7185769 2.076000e-04 8.924610e-02 3.101168e-01 2 9489811 9489856 46 - 1.873 1.930 0.193
ENSG00000151694 E011 238.8421276 8.270972e-05 2.273476e-03 2.812976e-02 2 9489857 9490228 372 - 2.351 2.408 0.191
ENSG00000151694 E012 104.8030647 1.539648e-04 5.099980e-02 2.235370e-01 2 9490229 9490358 130 - 1.996 2.053 0.191
ENSG00000151694 E013 119.2444730 1.822788e-04 1.713330e-02 1.144552e-01 2 9490359 9490518 160 - 2.047 2.113 0.219
ENSG00000151694 E014 67.5382215 3.670293e-04 8.712364e-01 9.557462e-01 2 9491101 9491151 51 - 1.833 1.839 0.021
ENSG00000151694 E015 7.2360410 2.124353e-03 5.217254e-06 1.950016e-04 2 9491152 9492484 1333 - 0.620 1.102 1.877
ENSG00000151694 E016 85.2550754 1.981757e-04 2.365165e-01 5.254905e-01 2 9492898 9492986 89 - 1.917 1.955 0.130
ENSG00000151694 E017 0.6084616 1.473297e-02 7.843205e-01 9.168385e-01 2 9492987 9493153 167 - 0.225 0.184 -0.360
ENSG00000151694 E018 62.7461510 2.411763e-04 7.832828e-01 9.165837e-01 2 9493747 9493788 42 - 1.809 1.799 -0.034
ENSG00000151694 E019 55.9691943 2.873490e-04 3.146920e-01 6.076399e-01 2 9493789 9493825 37 - 1.774 1.734 -0.135
ENSG00000151694 E020 32.4764785 4.321621e-04 9.315746e-01 9.800034e-01 2 9494637 9494767 131 - 1.526 1.522 -0.014
ENSG00000151694 E021 16.1784433 6.404595e-03 7.641708e-08 4.565202e-06 2 9494768 9495691 924 - 0.972 1.408 1.554
ENSG00000151694 E022 1.3586624 1.204022e-02 2.506631e-01 5.417518e-01 2 9496251 9496267 17 - 0.280 0.455 1.032
ENSG00000151694 E023 7.0751394 1.937838e-03 7.904700e-04 1.248776e-02 2 9496268 9497113 846 - 0.705 1.054 1.340
ENSG00000151694 E024 56.5321481 2.837630e-03 2.452220e-01 5.356744e-01 2 9497114 9497248 135 - 1.784 1.732 -0.176
ENSG00000151694 E025 1.1169088 3.801107e-02 2.334762e-01 5.223939e-01 2 9499207 9499287 81 - 0.225 0.413 1.225
ENSG00000151694 E026 1.3867016 7.982230e-02 4.208391e-03 4.401306e-02 2 9499288 9499431 144 - 0.089 0.562 3.547
ENSG00000151694 E027 0.0000000       2 9499432 9499437 6 -      
ENSG00000151694 E028 0.0000000       2 9499438 9499491 54 -      
ENSG00000151694 E029 0.6345490 1.515388e-02 1.305608e-02 9.566181e-02 2 9499492 9499710 219 - 0.000 0.366 13.464
ENSG00000151694 E030 9.1232024 7.892520e-03 5.308368e-07 2.624212e-05 2 9499711 9501950 2240 - 0.686 1.199 1.945
ENSG00000151694 E031 1.2514760 1.424774e-02 3.034024e-02 1.638829e-01 2 9501951 9502172 222 - 0.162 0.494 2.225
ENSG00000151694 E032 63.4711353 2.688449e-04 1.060767e-01 3.410278e-01 2 9502173 9502276 104 - 1.837 1.776 -0.205
ENSG00000151694 E033 118.6556952 1.621133e-04 6.775468e-01 8.663745e-01 2 9505166 9505365 200 - 2.083 2.072 -0.037
ENSG00000151694 E034 83.6689209 5.637323e-04 8.564419e-02 3.028543e-01 2 9509979 9510131 153 - 1.954 1.896 -0.194
ENSG00000151694 E035 41.3070242 1.480568e-03 2.258857e-02 1.367818e-01 2 9517901 9517989 89 - 1.676 1.565 -0.378
ENSG00000151694 E036 54.8556085 3.383752e-04 2.948881e-02 1.613687e-01 2 9518103 9518247 145 - 1.787 1.699 -0.299
ENSG00000151694 E037 56.3592094 2.652941e-04 1.968741e-03 2.525740e-02 2 9521203 9521316 114 - 1.813 1.689 -0.420
ENSG00000151694 E038 1.1133584 3.079979e-02 2.306743e-01 5.191181e-01 2 9521317 9521321 5 - 0.225 0.413 1.225
ENSG00000151694 E039 0.3722815 1.663281e-02 4.919377e-01   2 9521322 9521595 274 - 0.089 0.184 1.225
ENSG00000151694 E040 1.2357059 1.153881e-01 4.316131e-01 7.093248e-01 2 9521596 9522438 843 - 0.280 0.413 0.810
ENSG00000151694 E041 1.2350156 1.056365e-02 3.853029e-01 6.713486e-01 2 9522439 9523248 810 - 0.280 0.413 0.810
ENSG00000151694 E042 54.3780217 2.685135e-04 2.714766e-02 1.531411e-01 2 9523249 9523338 90 - 1.784 1.694 -0.304
ENSG00000151694 E043 0.7544805 3.914687e-02 6.780128e-02 2.627734e-01 2 9523339 9523348 10 - 0.089 0.366 2.547
ENSG00000151694 E044 9.3864685 1.872151e-03 6.774603e-03 6.168932e-02 2 9523904 9526110 2207 - 0.879 1.128 0.921
ENSG00000151694 E045 59.8851927 2.524513e-04 3.892822e-01 6.750594e-01 2 9526111 9526244 134 - 1.800 1.767 -0.112
ENSG00000151694 E046 1.1050164 1.132516e-02 5.758240e-01 8.101975e-01 2 9526245 9526264 20 - 0.280 0.366 0.547
ENSG00000151694 E047 0.6342667 1.427124e-02 1.300687e-02 9.540496e-02 2 9527501 9527785 285 - 0.000 0.366 13.474
ENSG00000151694 E048 63.3858153 2.641084e-03 2.864533e-01 5.800471e-01 2 9527786 9527954 169 - 1.830 1.784 -0.155
ENSG00000151694 E049 0.0000000       2 9529488 9529804 317 -      
ENSG00000151694 E050 40.5437506 3.457540e-04 1.347506e-01 3.902481e-01 2 9535834 9535922 89 - 1.650 1.580 -0.238
ENSG00000151694 E051 40.6635874 5.310236e-03 2.196035e-01 5.062430e-01 2 9536698 9536773 76 - 1.650 1.583 -0.228
ENSG00000151694 E052 37.7381019 1.241277e-02 2.225071e-01 5.098988e-01 2 9536774 9536828 55 - 1.626 1.542 -0.284
ENSG00000151694 E053 0.1176306 1.171948e-02 6.271794e-01   2 9538058 9538077 20 - 0.089 0.000 -11.814
ENSG00000151694 E054 36.4799108 4.337509e-03 4.795990e-02 2.154843e-01 2 9543153 9543220 68 - 1.623 1.512 -0.380
ENSG00000151694 E055 22.4720118 6.288154e-04 4.967842e-02 2.198716e-01 2 9543221 9543226 6 - 1.425 1.302 -0.425
ENSG00000151694 E056 34.9124379 3.839885e-04 8.853695e-02 3.086318e-01 2 9543227 9543285 59 - 1.594 1.508 -0.293
ENSG00000151694 E057 0.3806233 1.586137e-02 7.650787e-02   2 9543696 9543760 65 - 0.000 0.254 12.752
ENSG00000151694 E058 0.3621491 1.649078e-02 6.841933e-01   2 9551475 9551757 283 - 0.162 0.102 -0.775
ENSG00000151694 E059 0.9974535 1.215138e-02 1.002569e-01 3.307834e-01 2 9554709 9554780 72 - 0.162 0.413 1.810
ENSG00000151694 E060 2.3295497 3.580329e-02 5.980999e-01 8.237969e-01 2 9554896 9554945 50 - 0.483 0.562 0.377
ENSG00000151694 E061 52.6405379 2.647626e-04 1.990057e-01 4.805412e-01 2 9555509 9555848 340 - 1.754 1.701 -0.179
ENSG00000151694 E062 0.0000000       2 9556591 9556732 142 -      

Help

Please Click HERE to learn more details about the results from DEXseq.