ENSG00000151718

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000403733 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding protein_coding 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 2.1133165 1.2591685 0.0000000 0.5497546 0.0000000 -6.9877398 0.17678333 0.168400 0.000000 -0.168400 0.02944595 0.02944595 FALSE TRUE
ENST00000427431 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding nonsense_mediated_decay 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 1.6573392 1.3282105 3.6438070 0.8651574 2.2681207 1.4490953 0.12150000 0.171725 0.192775 0.021050 1.00000000 0.02944595 FALSE TRUE
ENST00000448232 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding protein_coding 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 0.9933839 0.6053936 1.5218183 0.3543154 0.6907094 1.3156638 0.07232500 0.078025 0.075350 -0.002675 0.98438399 0.02944595 FALSE TRUE
ENST00000504005 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding protein_coding 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 1.7175716 1.1279519 2.2673531 0.6923814 1.3657658 1.0009184 0.12820833 0.134200 0.120800 -0.013400 0.98220216 0.02944595 FALSE TRUE
ENST00000508747 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding protein_coding 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 2.0246078 1.7227119 3.4088718 0.4255941 1.1665182 0.9804886 0.14931667 0.210675 0.168950 -0.041725 0.87162258 0.02944595 FALSE TRUE
ENST00000513834 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding protein_coding 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 1.1474170 0.5341117 1.9045491 0.5341117 1.9045491 1.8150298 0.08689167 0.064425 0.122275 0.057850 0.93681180 0.02944595 FALSE TRUE
ENST00000515284 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding retained_intron 13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 1.4810579 0.9501248 0.8769797 0.2686523 0.5244917 -0.1143208 0.11456667 0.114550 0.044250 -0.070300 0.57288432 0.02944595   FALSE
MSTRG.22594.1 ENSG00000151718 No_inf pgKDN_inf WWC2 protein_coding   13.61233 8.011744 18.9739 0.4476204 1.356723 1.242789 2.2011936 0.4840715 4.5878861 0.3010222 0.8774061 3.2181789 0.13560833 0.057975 0.236025 0.178050 0.20100887 0.02944595 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151718 E001 0.5961232 0.0327523316 5.430149e-01 0.790080214 4 183099210 183099256 47 + 0.228 0.129 -1.000
ENSG00000151718 E002 1.2044561 0.0109272450 8.327847e-01 0.939692203 4 183099257 183099338 82 + 0.345 0.309 -0.222
ENSG00000151718 E003 3.1501109 0.0046000373 8.778974e-01 0.958506868 4 183099339 183099491 153 + 0.596 0.614 0.082
ENSG00000151718 E004 3.4863917 0.0058236791 2.941872e-01 0.587547995 4 183099492 183099622 131 + 0.682 0.534 -0.652
ENSG00000151718 E005 1.3321621 0.0782205574 8.482731e-01 0.946285748 4 183193599 183193614 16 + 0.345 0.377 0.192
ENSG00000151718 E006 3.1372114 0.0052174921 7.952147e-01 0.922187770 4 183193615 183193708 94 + 0.614 0.576 -0.170
ENSG00000151718 E007 0.0000000       4 183203516 183203603 88 +      
ENSG00000151718 E008 8.5385157 0.0252074814 2.139168e-01 0.499182115 4 183207953 183208156 204 + 1.008 0.859 -0.558
ENSG00000151718 E009 4.0859814 0.0649504773 3.213836e-01 0.614452912 4 183208949 183208978 30 + 0.740 0.576 -0.701
ENSG00000151718 E010 3.3349926 0.0308959460 9.900923e-03 0.079724754 4 183208979 183209025 47 + 0.727 0.309 -2.059
ENSG00000151718 E011 4.6561776 0.0764507572 4.520955e-02 0.207889174 4 183240183 183240262 80 + 0.827 0.488 -1.459
ENSG00000151718 E012 9.0341275 0.0935183390 3.429462e-01 0.634280801 4 183245416 183245545 130 + 1.022 0.899 -0.459
ENSG00000151718 E013 9.6157846 0.0123462241 1.466520e-01 0.407683374 4 183248714 183248860 147 + 1.056 0.899 -0.585
ENSG00000151718 E014 6.3146479 0.0037623921 4.305775e-01 0.708422811 4 183249920 183249993 74 + 0.815 0.899 0.322
ENSG00000151718 E015 13.0803539 0.0010571021 6.574897e-01 0.856691981 4 183253757 183253999 243 + 1.118 1.151 0.119
ENSG00000151718 E016 9.4884385 0.0015199408 7.763431e-02 0.285052012 4 183259639 183259728 90 + 1.056 0.879 -0.659
ENSG00000151718 E017 22.9049022 0.0006231581 1.536297e-01 0.418435615 4 183260910 183261385 476 + 1.390 1.294 -0.333
ENSG00000151718 E018 8.2120174 0.0414862102 9.180754e-01 0.974253897 4 183261386 183261532 147 + 0.952 0.935 -0.064
ENSG00000151718 E019 8.2099372 0.0017023776 6.872536e-01 0.870967017 4 183264978 183265107 130 + 0.961 0.917 -0.162
ENSG00000151718 E020 10.6026037 0.0013234511 2.323919e-01 0.521070231 4 183265688 183265768 81 + 1.082 0.969 -0.415
ENSG00000151718 E021 5.1749967 0.0031959317 2.838148e-01 0.577516854 4 183265865 183265868 4 + 0.815 0.682 -0.541
ENSG00000151718 E022 10.7528393 0.0013931274 7.308284e-01 0.893069085 4 183265869 183265951 83 + 1.063 1.029 -0.123
ENSG00000151718 E023 13.1502095 0.0010596041 3.918882e-01 0.676962238 4 183268971 183269118 148 + 1.156 1.082 -0.267
ENSG00000151718 E024 4.9128218 0.0032990160 5.386405e-02 0.230912003 4 183269119 183269163 45 + 0.827 0.576 -1.045
ENSG00000151718 E025 0.0000000       4 183269419 183269603 185 +      
ENSG00000151718 E026 0.5902332 0.0292750406 1.154213e-01 0.358177930 4 183269762 183269850 89 + 0.271 0.001 -9.456
ENSG00000151718 E027 0.0000000       4 183269851 183269994 144 +      
ENSG00000151718 E028 0.3709943 0.0168219613 2.411025e-01   4 183269995 183270048 54 + 0.069 0.228 2.000
ENSG00000151718 E029 10.0570572 0.0112790528 9.141103e-01 0.972928075 4 183271080 183271211 132 + 1.022 1.029 0.026
ENSG00000151718 E030 6.5757713 0.0083779227 2.641165e-01 0.557181550 4 183271212 183271241 30 + 0.816 0.935 0.459
ENSG00000151718 E031 9.5043346 0.0015441024 9.399904e-02 0.318992279 4 183280776 183280897 122 + 0.944 1.094 0.552
ENSG00000151718 E032 1.7211860 0.0081809607 6.953182e-02 0.266578803 4 183280898 183280969 72 + 0.309 0.576 1.415
ENSG00000151718 E033 2.0914249 0.0081179379 3.278016e-02 0.171687927 4 183280970 183281386 417 + 0.345 0.649 1.515
ENSG00000151718 E034 1.9353579 0.0855384120 8.598105e-01 0.951339028 4 183282607 183282707 101 + 0.463 0.436 -0.138
ENSG00000151718 E035 16.6414013 0.0010102728 1.746720e-01 0.448494701 4 183282708 183282906 199 + 1.191 1.287 0.335
ENSG00000151718 E036 16.9545113 0.0009809409 7.801766e-01 0.915257470 4 183284226 183284390 165 + 1.228 1.246 0.061
ENSG00000151718 E037 11.0666394 0.0158493212 1.979102e-01 0.479303399 4 183285967 183286059 93 + 1.106 0.969 -0.502
ENSG00000151718 E038 18.3198850 0.0007685132 1.917939e-01 0.471520278 4 183289393 183289635 243 + 1.298 1.201 -0.342
ENSG00000151718 E039 13.9891443 0.0009606368 3.703454e-01 0.658669636 4 183312341 183312468 128 + 1.182 1.106 -0.270
ENSG00000151718 E040 202.5039713 0.0002526778 4.867681e-05 0.001300959 4 183315663 183320777 5115 + 2.264 2.330 0.221

Help

Please Click HERE to learn more details about the results from DEXseq.