ENSG00000151790

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000536354 ENSG00000151790 No_inf pgKDN_inf TDO2 protein_coding protein_coding 137.9281 14.91792 183.7998 0.9021504 4.727104 3.622128 130.016082 7.758379 176.6558185 0.9070294 5.4880979 4.507266 0.81262500 0.521000 0.960750 0.439750 4.576389e-27 4.576389e-27 FALSE TRUE
MSTRG.22463.4 ENSG00000151790 No_inf pgKDN_inf TDO2 protein_coding   137.9281 14.91792 183.7998 0.9021504 4.727104 3.622128 1.065618 2.896910 0.0000000 1.4585178 0.0000000 -8.183343 0.07153333 0.213175 0.000000 -0.213175 1.501267e-03 4.576389e-27 FALSE TRUE
MSTRG.22463.7 ENSG00000151790 No_inf pgKDN_inf TDO2 protein_coding   137.9281 14.91792 183.7998 0.9021504 4.727104 3.622128 1.908977 1.388067 2.8314861 0.9205829 1.3954661 1.023212 0.03600833 0.085425 0.015575 -0.069850 8.281822e-01 4.576389e-27 FALSE TRUE
MSTRG.22463.8 ENSG00000151790 No_inf pgKDN_inf TDO2 protein_coding   137.9281 14.91792 183.7998 0.9021504 4.727104 3.622128 0.706919 1.561855 0.2618908 1.5618548 0.2618908 -2.531369 0.03180833 0.092725 0.001325 -0.091400 7.277996e-01 4.576389e-27 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151790 E001 0.1187032 0.0118448552 3.737865e-01   4 155854738 155854756 19 + 0.031 0.000 -7.740
ENSG00000151790 E002 0.1187032 0.0118448552 3.737865e-01   4 155854757 155854761 5 + 0.031 0.000 -9.631
ENSG00000151790 E003 0.1187032 0.0118448552 3.737865e-01   4 155854762 155854770 9 + 0.031 0.000 -9.631
ENSG00000151790 E004 0.2459655 0.0166490623 6.652409e-02   4 155854771 155854864 94 + 0.031 0.256 3.425
ENSG00000151790 E005 0.4979097 0.0154982503 1.089151e-03   4 155855302 155855330 29 + 0.031 0.532 5.010
ENSG00000151790 E006 0.8693123 0.0880226401 1.022016e-04 0.002418668 4 155858848 155858898 51 + 0.060 0.700 4.748
ENSG00000151790 E007 0.1268540 0.0122681416 1.899688e-02   4 155864512 155865102 591 + 0.000 0.256 13.579
ENSG00000151790 E008 0.4976273 0.0152464420 1.093703e-03   4 155883932 155884099 168 + 0.031 0.532 5.010
ENSG00000151790 E009 1.2110718 0.1394212265 1.438248e-02 0.102120159 4 155903593 155903692 100 + 0.161 0.624 2.841
ENSG00000151790 E010 0.2438580 0.0162890552 6.669303e-02   4 155903693 155903695 3 + 0.031 0.256 3.425
ENSG00000151790 E011 30.1419398 0.0014668667 6.861252e-01 0.870355197 4 155903696 155903793 98 + 1.267 1.232 -0.123
ENSG00000151790 E012 65.0587347 0.0019248189 2.846344e-01 0.578318813 4 155904018 155904123 106 + 1.590 1.520 -0.242
ENSG00000151790 E013 69.8880352 0.0002242540 1.393936e-01 0.396969712 4 155905067 155905157 91 + 1.622 1.530 -0.315
ENSG00000151790 E014 1.8087945 0.0095392434 4.107374e-02 0.196650791 4 155905158 155905794 637 + 0.260 0.624 1.966
ENSG00000151790 E015 8.1910117 0.0168220618 4.115982e-05 0.001129727 4 155905820 155907721 1902 + 0.675 1.189 1.951
ENSG00000151790 E016 58.8678886 0.0004679641 4.529140e-01 0.725863966 4 155907722 155907792 71 + 1.547 1.498 -0.166
ENSG00000151790 E017 68.5687779 0.0045918225 1.688324e-01 0.440213144 4 155908887 155909014 128 + 1.615 1.520 -0.324
ENSG00000151790 E018 82.9867672 0.0001988678 8.309545e-03 0.070934947 4 155910025 155910184 160 + 1.700 1.540 -0.544
ENSG00000151790 E019 37.3452106 0.0079364170 2.477331e-01 0.538484998 4 155910185 155910211 27 + 1.361 1.252 -0.382
ENSG00000151790 E020 73.9367634 0.0002257590 5.098004e-01 0.767518300 4 155911497 155911604 108 + 1.642 1.605 -0.125
ENSG00000151790 E021 42.0922951 0.0050654788 5.177051e-01 0.773156666 4 155914323 155914340 18 + 1.396 1.451 0.190
ENSG00000151790 E022 76.0327935 0.0003042967 8.713281e-01 0.955763285 4 155914341 155914434 94 + 1.649 1.662 0.043
ENSG00000151790 E023 64.5280711 0.0002520868 4.006033e-01 0.683955055 4 155915855 155915912 58 + 1.576 1.631 0.186
ENSG00000151790 E024 82.5113287 0.0002306885 3.017345e-01 0.594974623 4 155917395 155917474 80 + 1.680 1.738 0.199
ENSG00000151790 E025 74.0977246 0.0008245108 2.210663e-01 0.508139806 4 155918149 155918239 91 + 1.632 1.705 0.247
ENSG00000151790 E026 2.0057800 0.0527993110 2.296131e-01 0.518247380 4 155918804 155918859 56 + 0.356 0.000 -13.194
ENSG00000151790 E027 259.3380904 0.0007855254 6.174218e-01 0.834336248 4 155919837 155920406 570 + 2.175 2.193 0.059

Help

Please Click HERE to learn more details about the results from DEXseq.