ENSG00000151893

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369151 ENSG00000151893 No_inf pgKDN_inf CACUL1 protein_coding protein_coding 6.700835 6.363266 8.023472 1.125859 0.8569893 0.3339908 3.9823173 4.0017600 4.1100136 0.05121676 0.0749080 0.03841382 0.63227500 0.690200 0.527375 -0.162825 0.7694003220 0.0001344221 FALSE TRUE
ENST00000481360 ENSG00000151893 No_inf pgKDN_inf CACUL1 protein_coding retained_intron 6.700835 6.363266 8.023472 1.125859 0.8569893 0.3339908 0.5131607 1.1881173 0.3513649 0.85333388 0.3513649 -1.72924063 0.06307500 0.140325 0.048900 -0.091425 0.7932122139 0.0001344221 FALSE TRUE
ENST00000489169 ENSG00000151893 No_inf pgKDN_inf CACUL1 protein_coding retained_intron 6.700835 6.363266 8.023472 1.125859 0.8569893 0.3339908 0.8543444 0.6762203 0.9881703 0.40450974 0.9881703 0.54061414 0.10645000 0.084625 0.094675 0.010050 0.8323176161 0.0001344221 FALSE FALSE
ENST00000490610 ENSG00000151893 No_inf pgKDN_inf CACUL1 protein_coding retained_intron 6.700835 6.363266 8.023472 1.125859 0.8569893 0.3339908 0.1322863 0.3968590 0.0000000 0.39685904 0.0000000 -5.34645715 0.02326667 0.069800 0.000000 -0.069800 0.8362878012 0.0001344221   FALSE
ENST00000493518 ENSG00000151893 No_inf pgKDN_inf CACUL1 protein_coding nonsense_mediated_decay 6.700835 6.363266 8.023472 1.125859 0.8569893 0.3339908 1.1552174 0.0000000 2.4837052 0.00000000 0.4062547 7.96214709 0.16614167 0.000000 0.317725 0.317725 0.0001344221 0.0001344221 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000151893 E001 0.0000000       10 118674167 118674460 294 -      
ENSG00000151893 E002 166.1068705 0.0002015359 1.427480e-06 6.320992e-05 10 118676411 118684555 8145 - 2.185 2.258 0.244
ENSG00000151893 E003 53.7810721 0.0003442752 1.125374e-03 1.642205e-02 10 118684556 118685958 1403 - 1.796 1.673 -0.416
ENSG00000151893 E004 4.0706562 0.0040287981 1.576457e-01 4.242747e-01 10 118685959 118685982 24 - 0.610 0.783 0.720
ENSG00000151893 E005 4.2998426 0.0034266661 4.769266e-01 7.432547e-01 10 118685983 118685996 14 - 0.680 0.764 0.347
ENSG00000151893 E006 11.1156899 0.0012873052 6.894272e-01 8.723213e-01 10 118685997 118686168 172 - 1.100 1.066 -0.123
ENSG00000151893 E007 3.7439685 0.0318663152 4.784342e-02 2.152111e-01 10 118686598 118686641 44 - 0.793 0.516 -1.191
ENSG00000151893 E008 0.1268540 0.0123055973 5.014087e-01   10 118686642 118686781 140 - 0.000 0.098 10.100
ENSG00000151893 E009 5.5499842 0.0253098187 1.351934e-02 9.779768e-02 10 118691265 118691403 139 - 0.945 0.633 -1.245
ENSG00000151893 E010 0.4910456 0.0364329678 9.439767e-01   10 118691404 118691565 162 - 0.168 0.178 0.099
ENSG00000151893 E011 0.1187032 0.0118414218 5.769678e-01   10 118693702 118693749 48 - 0.092 0.000 -10.800
ENSG00000151893 E012 0.7502944 0.2788338695 1.835198e-01 4.603916e-01 10 118694921 118695140 220 - 0.092 0.355 2.421
ENSG00000151893 E013 3.5243092 0.0125539709 2.806793e-01 5.739317e-01 10 118695141 118695230 90 - 0.721 0.578 -0.612
ENSG00000151893 E014 3.6652067 0.0039549488 8.643467e-01 9.530876e-01 10 118701306 118701408 103 - 0.680 0.658 -0.094
ENSG00000151893 E015 2.5930524 0.0135185654 2.220327e-01 5.093190e-01 10 118707492 118707528 37 - 0.461 0.633 0.799
ENSG00000151893 E016 2.9332929 0.0175716782 8.668720e-01 9.541243e-01 10 118707529 118707587 59 - 0.584 0.606 0.099
ENSG00000151893 E017 0.0000000       10 118726278 118726385 108 -      
ENSG00000151893 E018 0.1176306 0.0117253624 5.770984e-01   10 118729175 118729294 120 - 0.092 0.000 -10.801
ENSG00000151893 E019 4.5044825 0.0348393647 5.874415e-01 8.169250e-01 10 118729295 118729397 103 - 0.776 0.703 -0.293
ENSG00000151893 E020 4.2642834 0.0036293281 5.269465e-01 7.790858e-01 10 118730284 118730410 127 - 0.758 0.681 -0.316
ENSG00000151893 E021 11.9873195 0.0011583993 4.855178e-03 4.851939e-02 10 118754396 118755249 854 - 1.214 0.983 -0.836

Help

Please Click HERE to learn more details about the results from DEXseq.