ENSG00000152332

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000489294 ENSG00000152332 No_inf pgKDN_inf UHMK1 protein_coding protein_coding 36.37464 27.2391 44.13976 0.3698296 0.2797926 0.6961972 7.102095 0.000000 5.902220 0.0000000 2.571114 9.2075560 0.1807000 0.000000 0.133125 0.133125 0.04042053 0.01119794 FALSE TRUE
ENST00000538489 ENSG00000152332 No_inf pgKDN_inf UHMK1 protein_coding protein_coding 36.37464 27.2391 44.13976 0.3698296 0.2797926 0.6961972 4.503379 4.129379 9.380757 0.1288179 1.723470 1.1818272 0.1216083 0.151850 0.212975 0.061125 0.81598880 0.01119794 FALSE TRUE
ENST00000545294 ENSG00000152332 No_inf pgKDN_inf UHMK1 protein_coding protein_coding 36.37464 27.2391 44.13976 0.3698296 0.2797926 0.6961972 24.707185 22.967509 28.813067 0.4406454 1.658005 0.3270015 0.6956250 0.842975 0.652875 -0.190100 0.01119794 0.01119794 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000152332 E001 0.0000000       1 162497251 162497296 46 +      
ENSG00000152332 E002 0.0000000       1 162497805 162497817 13 +      
ENSG00000152332 E003 11.0991700 1.876316e-02 1.198298e-05 3.994376e-04 1 162497818 162498084 267 + 1.225 0.736 -1.828
ENSG00000152332 E004 11.6833353 1.234762e-03 9.353552e-03 7.696375e-02 1 162498085 162498268 184 + 1.181 0.954 -0.825
ENSG00000152332 E005 19.3116195 7.104605e-04 9.290225e-03 7.669661e-02 1 162499955 162500247 293 + 1.370 1.191 -0.630
ENSG00000152332 E006 0.4985712 2.541714e-02 1.725307e-01   1 162500248 162500912 665 + 0.080 0.276 2.134
ENSG00000152332 E007 21.9075420 6.552649e-04 6.473989e-05 1.645467e-03 1 162500913 162501104 192 + 1.449 1.182 -0.931
ENSG00000152332 E008 15.6705309 8.593491e-04 7.427907e-03 6.575032e-02 1 162503754 162503848 95 + 1.293 1.088 -0.726
ENSG00000152332 E009 11.9002329 1.304193e-03 1.499152e-03 2.047487e-02 1 162512500 162512576 77 + 1.203 0.924 -1.016
ENSG00000152332 E010 18.9386890 7.340387e-04 3.429976e-03 3.819788e-02 1 162512725 162512823 99 + 1.370 1.165 -0.721
ENSG00000152332 E011 18.0140934 8.977494e-04 3.594255e-02 1.818512e-01 1 162518102 162518190 89 + 1.331 1.182 -0.523
ENSG00000152332 E012 1398.9386512 6.294053e-05 2.831985e-19 7.204730e-17 1 162522404 162529631 7228 + 3.132 3.153 0.072

Help

Please Click HERE to learn more details about the results from DEXseq.