ENSG00000152520

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000380958 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding protein_coding 34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 2.6602203 2.5290833 3.4441517 1.7693318 0.3922550 0.4440237 0.10004167 0.043800 0.153900 0.110100 0.250198123 0.004761692 FALSE  
ENST00000399613 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding protein_coding 34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 2.4518740 3.4230167 1.4698341 1.2265058 0.9064615 -1.2140414 0.08254167 0.057550 0.064550 0.007000 0.914737220 0.004761692 FALSE  
MSTRG.7624.1 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 1.4282750 1.5545491 1.7261391 1.0966348 0.5874908 0.1501356 0.04918333 0.023575 0.075475 0.051900 0.436580646 0.004761692 FALSE  
MSTRG.7624.14 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 4.9470771 8.9746919 3.2027321 0.7242948 0.3384339 -1.4836684 0.14063333 0.147800 0.143425 -0.004375 1.000000000 0.004761692 FALSE  
MSTRG.7624.15 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 3.5951670 7.0477808 0.8682599 0.9351307 0.5223476 -3.0064948 0.09919167 0.117525 0.039825 -0.077700 0.379235403 0.004761692 FALSE  
MSTRG.7624.16 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 10.2436248 19.1851223 6.1148319 2.2603851 0.6209156 -1.6479976 0.28474167 0.309875 0.270475 -0.039400 0.844856520 0.004761692 FALSE  
MSTRG.7624.7 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 1.3799138 4.1397414 0.0000000 3.0220976 0.0000000 -8.6968776 0.02117500 0.063525 0.000000 -0.063525 0.698611122 0.004761692    
MSTRG.7624.8 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 0.9284377 0.2174368 1.5427693 0.2174368 1.0005514 2.7713061 0.04056667 0.003850 0.070700 0.066850 0.568775012 0.004761692 FALSE  
MSTRG.7624.9 ENSG00000152520 No_inf pgKDN_inf PAN3 protein_coding   34.63762 61.29672 22.4948 3.433445 0.4787743 -1.445812 1.1590150 3.1619742 0.0000000 0.8534104 0.0000000 -8.3092372 0.02241667 0.051100 0.000000 -0.051100 0.004761692 0.004761692 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000152520 E001 0.6181209 0.0195074118 0.561545938 0.80184318 13 28138487 28138505 19 + 0.252 0.163 -0.783
ENSG00000152520 E002 0.3722815 0.0165164564 0.806567006   13 28138506 28138544 39 + 0.144 0.116 -0.368
ENSG00000152520 E003 12.6918010 0.0012256773 0.002640148 0.03133532 13 28138545 28139032 488 + 1.253 1.006 -0.888
ENSG00000152520 E004 4.7245025 0.0031690188 0.881257995 0.96006158 13 28139033 28139087 55 + 0.726 0.709 -0.073
ENSG00000152520 E005 0.5078857 0.0157733384 0.286490092 0.58004712 13 28143193 28143231 39 + 0.000 0.207 11.764
ENSG00000152520 E006 0.2545247 0.2325054024 0.974289824   13 28152025 28152084 60 + 0.000 0.116 10.326
ENSG00000152520 E007 9.6597795 0.0055282324 0.207849742 0.49154468 13 28174272 28174393 122 + 1.065 0.943 -0.451
ENSG00000152520 E008 9.0888979 0.0015783855 0.931466229 0.97999201 13 28176493 28176559 67 + 0.948 0.958 0.038
ENSG00000152520 E009 7.0523847 0.0021817062 0.237290374 0.52627762 13 28177865 28177935 71 + 0.948 0.822 -0.481
ENSG00000152520 E010 2.9223015 0.0050419598 0.002054930 0.02608392 13 28197185 28197265 81 + 0.813 0.402 -1.854
ENSG00000152520 E011 3.2065105 0.0486774572 0.164952483 0.43442470 13 28197266 28197346 81 + 0.726 0.517 -0.921
ENSG00000152520 E012 9.4975593 0.0016265194 0.020081416 0.12730032 13 28220231 28220378 148 + 1.120 0.903 -0.799
ENSG00000152520 E013 0.0000000       13 28239557 28239578 22 +      
ENSG00000152520 E014 1.7756326 0.0726259165 0.010029836 0.08046246 13 28239579 28239696 118 + 0.000 0.496 13.208
ENSG00000152520 E015 1.2518834 0.1433186102 0.657407783 0.85664729 13 28239697 28240037 341 + 0.252 0.346 0.632
ENSG00000152520 E016 15.6942658 0.0008980962 0.827854705 0.93771968 13 28256292 28256539 248 + 1.157 1.177 0.068
ENSG00000152520 E017 9.7333961 0.0013994271 0.487505588 0.75091417 13 28260447 28260551 105 + 0.928 0.999 0.266
ENSG00000152520 E018 5.6977918 0.0025038027 0.309669276 0.60300173 13 28261401 28261458 58 + 0.863 0.746 -0.461
ENSG00000152520 E019 2.6123719 0.0055706555 0.941988781 0.98363264 13 28266715 28266717 3 + 0.526 0.517 -0.046
ENSG00000152520 E020 13.0639420 0.0012920143 0.005137320 0.05058904 13 28266718 28266876 159 + 1.253 1.025 -0.817
ENSG00000152520 E021 9.6083812 0.0014463811 0.006567382 0.06027998 13 28267095 28267211 117 + 1.145 0.895 -0.921
ENSG00000152520 E022 7.9733076 0.0698963253 0.917199676 0.97399530 13 28267300 28267401 102 + 0.886 0.912 0.098
ENSG00000152520 E023 14.0362057 0.0013953729 0.467341315 0.73578024 13 28270701 28270866 166 + 1.169 1.110 -0.212
ENSG00000152520 E024 10.0914523 0.0013672697 0.889542011 0.96325942 13 28271981 28272071 91 + 0.985 0.999 0.055
ENSG00000152520 E025 2.3710930 0.0077511730 0.881782068 0.96028165 13 28272072 28272313 242 + 0.472 0.496 0.117
ENSG00000152520 E026 4.6428062 0.0075256440 0.103495137 0.33627970 13 28274429 28274796 368 + 0.526 0.758 1.001
ENSG00000152520 E027 5.7857453 0.0024423293 0.016463464 0.11162043 13 28274797 28275083 287 + 0.526 0.851 1.369
ENSG00000152520 E028 3.0029379 0.0049420685 0.433849920 0.71113730 13 28275084 28275332 249 + 0.472 0.590 0.558
ENSG00000152520 E029 3.1124199 0.0044591322 0.987248847 0.99963779 13 28275333 28275524 192 + 0.574 0.573 -0.006
ENSG00000152520 E030 13.2828864 0.0012883194 0.032743892 0.17160714 13 28276644 28277236 593 + 0.948 1.149 0.736
ENSG00000152520 E031 11.5159078 0.0012436934 0.110748944 0.34929663 13 28277237 28277297 61 + 1.145 1.006 -0.506
ENSG00000152520 E032 15.4896398 0.0008946720 0.159859061 0.42737378 13 28277298 28277376 79 + 1.243 1.135 -0.386
ENSG00000152520 E033 4.0362050 0.0037465453 0.010269683 0.08169176 13 28277953 28278192 240 + 0.338 0.734 1.905
ENSG00000152520 E034 0.8682720 0.0138905037 0.965344293 0.99272752 13 28280389 28280411 23 + 0.252 0.246 -0.046
ENSG00000152520 E035 21.2265726 0.0006977035 0.363168262 0.65217940 13 28280412 28280541 130 + 1.339 1.278 -0.214
ENSG00000152520 E036 19.3204417 0.0008170078 0.451564810 0.72462649 13 28281315 28281379 65 + 1.213 1.271 0.204
ENSG00000152520 E037 28.9685581 0.0004705517 0.648854510 0.85190290 13 28287984 28288122 139 + 1.443 1.417 -0.089
ENSG00000152520 E038 23.3090714 0.0006413083 0.401809748 0.68493069 13 28292382 28292511 130 + 1.290 1.349 0.206
ENSG00000152520 E039 29.2839852 0.0004796440 0.511643652 0.76878008 13 28292512 28292660 149 + 1.398 1.439 0.144
ENSG00000152520 E040 170.1478099 0.0001882639 0.196242858 0.47687147 13 28292661 28293862 1202 + 2.155 2.188 0.109
ENSG00000152520 E041 35.7482000 0.0004038306 0.695714564 0.87579753 13 28293863 28294006 144 + 1.495 1.518 0.079
ENSG00000152520 E042 294.0464316 0.0001179057 0.185934188 0.46388077 13 28294007 28295335 1329 + 2.399 2.422 0.077

Help

Please Click HERE to learn more details about the results from DEXseq.