ENSG00000153029

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000282990 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding protein_coding 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 6.291463 4.032441 6.197703 1.4693453 1.4808723 0.6188331 0.22891667 0.207250 0.196575 -0.010675 9.863452e-01 3.878182e-09 FALSE TRUE
ENST00000367578 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding retained_intron 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 1.520150 1.745623 1.590174 0.1588764 0.3572933 -0.1337545 0.05950000 0.089525 0.049375 -0.040150 6.511797e-01 3.878182e-09 FALSE TRUE
ENST00000367580 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding protein_coding 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 4.559495 6.376696 4.642821 2.3072397 3.1399429 -0.4569640 0.17858333 0.312900 0.134925 -0.177975 6.699238e-01 3.878182e-09 FALSE TRUE
ENST00000438435 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding protein_coding_CDS_not_defined 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 1.489453 1.667613 2.179891 1.6676127 1.2656695 0.3844493 0.06068333 0.091700 0.071975 -0.019725 8.380412e-01 3.878182e-09 FALSE TRUE
ENST00000614012 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding protein_coding 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 6.901858 2.374407 8.280954 1.3747135 2.9446015 1.7979078 0.23908333 0.122600 0.274600 0.152000 7.600763e-01 3.878182e-09 FALSE TRUE
ENST00000684375 ENSG00000153029 No_inf pgKDN_inf MR1 protein_coding protein_coding_CDS_not_defined 27.77611 19.76264 31.82745 1.509526 2.04072 0.6872189 4.833127 0.000000 6.898570 0.0000000 1.1340802 9.4322432 0.14464167 0.000000 0.212650 0.212650 3.878182e-09 3.878182e-09 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000153029 E001 0.1187032 1.178927e-02 6.960764e-01   1 181033374 181033464 91 + 0.085 0.000 -10.474
ENSG00000153029 E002 0.1187032 1.178927e-02 6.960764e-01   1 181033887 181033930 44 + 0.085 0.000 -12.094
ENSG00000153029 E003 0.1265070 1.227800e-02 4.135545e-01   1 181033931 181033971 41 + 0.000 0.107 11.629
ENSG00000153029 E004 0.1265070 1.227800e-02 4.135545e-01   1 181033972 181033982 11 + 0.000 0.107 11.629
ENSG00000153029 E005 0.3724725 1.659430e-02 4.355217e-01   1 181033983 181033986 4 + 0.085 0.192 1.371
ENSG00000153029 E006 2.0495677 6.575611e-03 2.357157e-01 5.250489e-01 1 181033987 181034002 16 + 0.554 0.379 -0.892
ENSG00000153029 E007 3.6308398 3.869106e-03 2.584279e-01 5.507933e-01 1 181034003 181034009 7 + 0.725 0.578 -0.629
ENSG00000153029 E008 7.9690507 4.510431e-02 6.733233e-02 2.616921e-01 1 181034010 181034021 12 + 1.046 0.799 -0.936
ENSG00000153029 E009 11.7533347 1.273531e-03 9.051560e-02 3.124433e-01 1 181034022 181034074 53 + 1.163 1.020 -0.518
ENSG00000153029 E010 0.2537694 1.597143e-02 1.657893e-01   1 181036997 181037112 116 + 0.000 0.192 12.571
ENSG00000153029 E011 0.3550369 2.561431e-02 1.653654e-01   1 181044861 181044902 42 + 0.216 0.000 -13.496
ENSG00000153029 E012 40.4965775 1.500188e-03 1.143401e-02 8.788399e-02 1 181049052 181049312 261 + 1.669 1.544 -0.426
ENSG00000153029 E013 2.3572471 6.534376e-02 5.928087e-02 2.443386e-01 1 181049313 181049697 385 + 0.360 0.665 1.487
ENSG00000153029 E014 26.9989374 1.541256e-03 7.225278e-03 6.443257e-02 1 181050011 181050145 135 + 1.511 1.351 -0.552
ENSG00000153029 E015 35.4369305 4.026177e-04 3.965646e-02 1.930531e-01 1 181050146 181050286 141 + 1.604 1.500 -0.355
ENSG00000153029 E016 8.7300534 1.796127e-03 3.240215e-02 1.705120e-01 1 181050287 181051273 987 + 0.885 1.084 0.739
ENSG00000153029 E017 10.4058020 1.087841e-02 9.147149e-02 3.140508e-01 1 181052235 181052321 87 + 1.123 0.958 -0.603
ENSG00000153029 E018 23.3313662 6.481660e-04 1.592939e-01 4.266196e-01 1 181052322 181052510 189 + 1.421 1.334 -0.302
ENSG00000153029 E019 37.6805633 3.447642e-03 2.057341e-01 4.891150e-01 1 181053573 181053677 105 + 1.615 1.547 -0.233
ENSG00000153029 E020 613.8738329 6.399646e-05 2.841761e-08 1.851057e-06 1 181055225 181061938 6714 + 2.771 2.805 0.113

Help

Please Click HERE to learn more details about the results from DEXseq.