ENSG00000153214

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000283206 ENSG00000153214 No_inf pgKDN_inf TMEM87B protein_coding protein_coding 64.10163 53.92756 77.82864 1.992439 2.768926 0.5291963 28.093667 22.861557 33.1930946 0.9038882 1.4691099 0.5377631 0.4424000 0.427175 0.426350 -0.000825 1.000000e+00 1.592646e-05 FALSE TRUE
ENST00000463427 ENSG00000153214 No_inf pgKDN_inf TMEM87B protein_coding protein_coding_CDS_not_defined 64.10163 53.92756 77.82864 1.992439 2.768926 0.5291963 20.991463 7.812993 32.7525644 2.8809639 1.1234966 2.0662556 0.3078417 0.139400 0.421200 0.281800 1.837067e-01 1.592646e-05 FALSE TRUE
ENST00000471632 ENSG00000153214 No_inf pgKDN_inf TMEM87B protein_coding protein_coding 64.10163 53.92756 77.82864 1.992439 2.768926 0.5291963 1.308697 3.304363 0.4214084 1.9081504 0.2440073 -2.9416054 0.0243250 0.063900 0.005125 -0.058775 8.305917e-01 1.592646e-05 FALSE FALSE
ENST00000649734 ENSG00000153214 No_inf pgKDN_inf TMEM87B protein_coding protein_coding 64.10163 53.92756 77.82864 1.992439 2.768926 0.5291963 11.896273 19.185972 9.2278299 1.7193353 0.6389210 -1.0551778 0.1976333 0.355375 0.118550 -0.236825 1.592646e-05 1.592646e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000153214 E001 0.0000000       2 112055269 112055274 6 +      
ENSG00000153214 E002 0.0000000       2 112055275 112055296 22 +      
ENSG00000153214 E003 0.0000000       2 112055297 112055316 20 +      
ENSG00000153214 E004 9.8585304 4.580682e-03 1.740505e-01 4.475655e-01 2 112055317 112055482 166 + 1.094 0.969 -0.461
ENSG00000153214 E005 23.0876884 1.163483e-03 5.907965e-01 8.188681e-01 2 112055483 112055719 237 + 1.399 1.364 -0.119
ENSG00000153214 E006 9.2279478 1.605825e-03 7.198378e-02 2.720654e-01 2 112055720 112055756 37 + 1.086 0.919 -0.617
ENSG00000153214 E007 13.2791572 1.827721e-03 1.937745e-01 4.736262e-01 2 112059977 112060037 61 + 1.204 1.100 -0.374
ENSG00000153214 E008 18.9777220 8.600878e-04 4.294717e-02 2.020985e-01 2 112064162 112064253 92 + 1.364 1.227 -0.482
ENSG00000153214 E009 30.1431121 5.079458e-04 6.677837e-03 6.103414e-02 2 112066936 112067067 132 + 1.562 1.414 -0.510
ENSG00000153214 E010 20.5276098 6.618956e-04 8.812421e-03 7.386000e-02 2 112074912 112074962 51 + 1.411 1.239 -0.598
ENSG00000153214 E011 30.1399834 4.645760e-04 4.420464e-03 4.548668e-02 2 112077192 112077282 91 + 1.565 1.409 -0.534
ENSG00000153214 E012 27.3396281 5.007112e-04 3.704324e-01 6.587392e-01 2 112081057 112081118 62 + 1.478 1.426 -0.178
ENSG00000153214 E013 45.5106912 3.172373e-04 7.926296e-03 6.869858e-02 2 112081335 112081518 184 + 1.723 1.605 -0.403
ENSG00000153214 E014 15.0621438 2.479861e-03 4.994408e-02 2.206129e-01 2 112086005 112086023 19 + 1.275 1.125 -0.534
ENSG00000153214 E015 28.2965368 5.129732e-04 2.592554e-01 5.518212e-01 2 112086024 112086104 81 + 1.498 1.434 -0.220
ENSG00000153214 E016 16.5268569 8.207995e-04 8.019794e-01 9.261025e-01 2 112089625 112089631 7 + 1.235 1.252 0.059
ENSG00000153214 E017 41.1469539 4.522909e-04 2.192207e-02 1.344538e-01 2 112089632 112089718 87 + 1.676 1.568 -0.367
ENSG00000153214 E018 44.1269046 3.173301e-04 1.421860e-03 1.962801e-02 2 112091712 112091783 72 + 1.721 1.577 -0.492
ENSG00000153214 E019 0.1268540 1.234830e-02 5.083282e-01   2 112095189 112095227 39 + 0.000 0.097 9.449
ENSG00000153214 E020 1.3504475 9.602672e-03 6.940034e-01 8.749222e-01 2 112095228 112095299 72 + 0.341 0.400 0.343
ENSG00000153214 E021 57.3312298 1.041888e-03 3.894504e-05 1.074955e-03 2 112097044 112097152 109 + 1.844 1.673 -0.579
ENSG00000153214 E022 44.8321127 7.279886e-03 2.721279e-03 3.204074e-02 2 112097233 112097291 59 + 1.739 1.568 -0.580
ENSG00000153214 E023 61.2915550 4.058136e-03 1.018721e-03 1.521564e-02 2 112098595 112098698 104 + 1.864 1.713 -0.512
ENSG00000153214 E024 43.0124412 3.572489e-04 6.787156e-04 1.108261e-02 2 112100622 112100695 74 + 1.716 1.559 -0.532
ENSG00000153214 E025 0.2537694 1.606415e-02 2.232852e-01   2 112105867 112106001 135 + 0.000 0.177 10.385
ENSG00000153214 E026 42.3797576 3.602613e-04 3.220130e-02 1.697986e-01 2 112106002 112106075 74 + 1.685 1.585 -0.337
ENSG00000153214 E027 33.0742414 8.826221e-04 3.660899e-01 6.546866e-01 2 112107788 112107840 53 + 1.556 1.508 -0.165
ENSG00000153214 E028 27.6503210 4.975162e-04 8.627066e-01 9.525980e-01 2 112112899 112112929 31 + 1.453 1.461 0.029
ENSG00000153214 E029 756.0032688 5.637348e-05 1.623598e-43 1.787084e-40 2 112116084 112119318 3235 + 2.822 2.929 0.355

Help

Please Click HERE to learn more details about the results from DEXseq.