ENSG00000153443

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000283474 ENSG00000153443 No_inf pgKDN_inf UBALD1 protein_coding protein_coding 20.48594 28.65954 15.5386 5.069536 0.8935684 -0.8827342 12.601727 12.039562 13.1203976 1.1058442 0.6449372 0.1239299 0.67559167 0.449475 0.846475 0.397000 0.0009525143 0.0009525143 FALSE FALSE
ENST00000588691 ENSG00000153443 No_inf pgKDN_inf UBALD1 protein_coding non_stop_decay 20.48594 28.65954 15.5386 5.069536 0.8935684 -0.8827342 2.022016 6.066048 0.0000000 6.0660482 0.0000000 -9.2469895 0.04612500 0.138375 0.000000 -0.138375 0.9107083082 0.0009525143   FALSE
ENST00000590891 ENSG00000153443 No_inf pgKDN_inf UBALD1 protein_coding protein_coding 20.48594 28.65954 15.5386 5.069536 0.8935684 -0.8827342 2.419349 3.608175 1.3263294 0.1006602 0.1532878 -1.4369864 0.11925833 0.135000 0.087400 -0.047600 0.8058182597 0.0009525143 FALSE TRUE
ENST00000591113 ENSG00000153443 No_inf pgKDN_inf UBALD1 protein_coding protein_coding 20.48594 28.65954 15.5386 5.069536 0.8935684 -0.8827342 1.496801 3.030154 0.3278479 0.5922858 0.3278479 -3.1696985 0.06755000 0.116925 0.020550 -0.096375 0.1886700227 0.0009525143   FALSE
MSTRG.10558.7 ENSG00000153443 No_inf pgKDN_inf UBALD1 protein_coding   20.48594 28.65954 15.5386 5.069536 0.8935684 -0.8827342 1.208609 3.625827 0.0000000 2.0978146 0.0000000 -8.5061399 0.05030833 0.150925 0.000000 -0.150925 0.6488178244 0.0009525143 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000153443 E001 0.0000000       16 4608883 4608883 1 -      
ENSG00000153443 E002 0.0000000       16 4608884 4608885 2 -      
ENSG00000153443 E003 8.6581814 0.0082641248 6.050984e-01 0.8278468534 16 4608886 4609034 149 - 0.939 0.990 0.188
ENSG00000153443 E004 3.6597668 0.0135501609 1.212817e-01 0.3686433968 16 4609035 4609052 18 - 0.772 0.571 -0.852
ENSG00000153443 E005 9.3104128 0.0048157423 8.577925e-02 0.3032126161 16 4609053 4609130 78 - 1.093 0.934 -0.584
ENSG00000153443 E006 28.5637436 0.0167681518 7.539310e-01 0.9031878773 16 4609131 4609367 237 - 1.444 1.463 0.067
ENSG00000153443 E007 38.1590576 0.0004292934 7.889394e-02 0.2879168505 16 4609368 4609720 353 - 1.527 1.606 0.270
ENSG00000153443 E008 11.5230408 0.0042552116 7.612889e-02 0.2819251133 16 4609721 4609830 110 - 1.172 1.023 -0.537
ENSG00000153443 E009 10.2677530 0.0113705078 1.794141e-02 0.1180495169 16 4609831 4609908 78 - 1.162 0.944 -0.797
ENSG00000153443 E010 10.4159876 0.0013848861 4.380423e-02 0.2044071252 16 4609909 4609983 75 - 1.144 0.972 -0.626
ENSG00000153443 E011 7.3783196 0.0021240441 2.185169e-03 0.0272749096 16 4609984 4610492 509 - 0.671 1.007 1.310
ENSG00000153443 E012 13.0383295 0.0011588665 3.226625e-01 0.6155919579 16 4610493 4610555 63 - 1.180 1.103 -0.277
ENSG00000153443 E013 2.8816601 0.0511795790 4.481373e-02 0.2070221509 16 4610556 4610656 101 - 0.348 0.672 1.588
ENSG00000153443 E014 12.3269331 0.0015686837 1.441328e-02 0.1022984194 16 4610657 4611523 867 - 0.969 1.177 0.755
ENSG00000153443 E015 4.9262576 0.0179887751 2.277438e-05 0.0006889025 16 4613960 4614492 533 - 0.284 0.904 2.925
ENSG00000153443 E016 0.7533168 0.0134666758 2.473098e-01 0.5379257216 16 4614493 4614677 185 - 0.117 0.295 1.662
ENSG00000153443 E017 13.1464867 0.0011117435 1.313413e-01 0.3845064552 16 4614678 4614764 87 - 1.206 1.090 -0.417
ENSG00000153443 E018 9.2370824 0.0549354814 5.206765e-01 0.7748515174 16 4614765 4614888 124 - 1.048 0.963 -0.313
ENSG00000153443 E019 0.3550369 0.0235962437 4.168372e-02   16 4614917 4615027 111 - 0.284 0.000 -10.400

Help

Please Click HERE to learn more details about the results from DEXseq.