ENSG00000153531

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375418 ENSG00000153531 No_inf pgKDN_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 4.242159 0.05368568 0.08741726 3.661188 0.10259868 0.05787324 0.19859442 0.05787324 0.07156158 1.619786 0.0581000 0.121575 0.046100 -0.075475 0.7008091017 0.0008829438 FALSE TRUE
ENST00000612156 ENSG00000153531 No_inf pgKDN_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 4.242159 0.05368568 0.08741726 3.661188 0.09878524 0.26823727 0.02811845 0.02112232 0.02811845 -2.867754 0.2951500 0.878425 0.007025 -0.871400 0.0008829438 0.0008829438 FALSE TRUE
ENST00000682618 ENSG00000153531 No_inf pgKDN_inf ADPRHL1 protein_coding protein_coding 4.206371 0.3261105 4.242159 0.05368568 0.08741726 3.661188 3.42887135 0.00000000 2.96927797 0.00000000 0.99098234 8.218819 0.5373833 0.000000 0.709750 0.709750 0.1698016051 0.0008829438 FALSE TRUE
MSTRG.8088.3 ENSG00000153531 No_inf pgKDN_inf ADPRHL1 protein_coding   4.206371 0.3261105 4.242159 0.05368568 0.08741726 3.661188 0.53371122 0.00000000 1.04616768 0.00000000 1.04616768 6.722695 0.1044250 0.000000 0.237125 0.237125 0.9256310822 0.0008829438 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000153531 E001 0.3533378 0.01667639 1.000000000   13 113399611 113399615 5 - 0.117 0.000 -27.567
ENSG00000153531 E002 83.0823883 0.29304629 0.007957038 0.0689184 13 113399616 113408220 8605 - 1.841 1.394 -1.523
ENSG00000153531 E003 0.1170040 0.01197672 0.298058755   13 113409355 113409375 21 - 0.043 0.000 -25.981
ENSG00000153531 E004 2.0323273 0.09322399 0.158126535 0.4249537 13 113410856 113410975 120 - 0.389 0.437 0.263
ENSG00000153531 E005 0.0000000       13 113421940 113421944 5 -      
ENSG00000153531 E006 0.6086179 0.01722132 0.031475222 0.1674642 13 113421945 113422825 881 - 0.117 0.334 1.901
ENSG00000153531 E007 0.2441403 0.01684979 0.046695851   13 113422826 113422979 154 - 0.043 0.198 2.486
ENSG00000153531 E008 0.3628435 0.01746621 0.109259150   13 113424217 113424349 133 - 0.082 0.198 1.486
ENSG00000153531 E009 0.4808523 0.01640569 0.188189832   13 113425052 113425179 128 - 0.117 0.198 0.901
ENSG00000153531 E010 0.2455571 0.01711253 0.046595350   13 113428952 113429092 141 - 0.043 0.198 2.485
ENSG00000153531 E011 0.0000000       13 113433742 113433867 126 -      
ENSG00000153531 E012 0.3716209 0.01774423 0.005552664   13 113444425 113444589 165 - 0.043 0.334 3.486
ENSG00000153531 E013 0.0000000       13 113448999 113449277 279 -      
ENSG00000153531 E014 0.1271363 0.01281969 0.012744525   13 113453224 113453488 265 - 0.000 0.198 30.847

Help

Please Click HERE to learn more details about the results from DEXseq.