ENSG00000153922

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000505982 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding retained_intron 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 0.3568888 0.8895873 0.0000000 0.4174163 0.0000000 -6.4911913 0.02327500 0.060200 0.000000 -0.060200 0.14227181 0.03824164   FALSE
ENST00000511067 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding protein_coding 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 1.0991742 1.4568014 0.8222537 0.1047408 0.3971002 -0.8175783 0.07491667 0.111800 0.049075 -0.062725 0.56331611 0.03824164 FALSE TRUE
ENST00000512392 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding retained_intron 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 1.0732961 2.1961536 0.3566556 0.5079895 0.1850153 -2.5890359 0.07645000 0.165600 0.020750 -0.144850 0.03824164 0.03824164   FALSE
ENST00000512844 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding nonsense_mediated_decay 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 1.7233495 1.1180833 1.6706952 1.1180833 1.6706952 0.5751845 0.09995833 0.076475 0.088800 0.012325 1.00000000 0.03824164 FALSE TRUE
ENST00000514344 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding retained_intron 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 1.0969977 1.5149410 0.8979337 0.6033602 0.5738097 -0.7480945 0.08099167 0.113025 0.065325 -0.047700 0.81250008 0.03824164 FALSE TRUE
ENST00000706141 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding nonsense_mediated_decay 15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 2.1175346 0.9342449 3.2026131 0.3741522 0.3899504 1.7665142 0.13805833 0.068625 0.201425 0.132800 0.41981222 0.03824164 FALSE TRUE
MSTRG.23271.3 ENSG00000153922 No_inf pgKDN_inf CHD1 protein_coding   15.70144 13.56773 16.8899 1.178544 1.589946 0.3157724 5.0545867 3.4725418 6.1629168 0.1076414 0.5443287 0.8258117 0.32678333 0.264900 0.368500 0.103600 0.68177999 0.03824164 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000153922 E001 6.8745523 0.0038447306 3.018679e-01 0.5951072959 5 98853985 98855203 1219 - 0.842 0.949 0.408
ENSG00000153922 E002 0.7350599 0.0440596449 8.070268e-01 0.9288123201 5 98855204 98855240 37 - 0.220 0.259 0.305
ENSG00000153922 E003 23.0463515 0.0022873970 6.773908e-02 0.2626803599 5 98855241 98855731 491 - 1.323 1.438 0.397
ENSG00000153922 E004 17.1317039 0.0027344004 3.806345e-01 0.6670660752 5 98855732 98856019 288 - 1.227 1.290 0.222
ENSG00000153922 E005 19.0503056 0.0008378038 1.150077e-02 0.0881709273 5 98856020 98856282 263 - 1.215 1.382 0.585
ENSG00000153922 E006 16.0382119 0.0025194635 3.580328e-01 0.6475960995 5 98856283 98856424 142 - 1.197 1.265 0.239
ENSG00000153922 E007 14.1632754 0.0222349719 7.484690e-01 0.9006886258 5 98856425 98856566 142 - 1.166 1.196 0.106
ENSG00000153922 E008 18.7565360 0.0017475218 5.212858e-01 0.7753053064 5 98856567 98856725 159 - 1.314 1.271 -0.149
ENSG00000153922 E009 22.5243440 0.0007090207 2.557489e-01 0.5477847783 5 98858180 98858390 211 - 1.337 1.406 0.242
ENSG00000153922 E010 1.1240553 0.0111292399 4.546271e-02 0.2085553837 5 98858391 98858963 573 - 0.159 0.463 2.112
ENSG00000153922 E011 7.6203607 0.0022404084 1.155389e-01 0.3583366592 5 98858964 98859015 52 - 0.855 1.011 0.585
ENSG00000153922 E012 10.2861691 0.0014185354 3.398036e-01 0.6314418601 5 98859972 98860068 97 - 1.011 1.094 0.305
ENSG00000153922 E013 3.5013242 0.0047627573 3.001350e-04 0.0058082093 5 98860069 98860682 614 - 0.366 0.844 2.179
ENSG00000153922 E014 14.1399901 0.0029337433 8.604974e-01 0.9516753534 5 98863408 98863586 179 - 1.185 1.172 -0.045
ENSG00000153922 E015 12.2539440 0.0255606314 2.630233e-01 0.5559158614 5 98868495 98868635 141 - 1.172 1.055 -0.424
ENSG00000153922 E016 0.8442573 0.0125881360 3.818265e-01 0.6681792398 5 98868930 98869013 84 - 0.322 0.189 -1.017
ENSG00000153922 E017 3.6883571 0.0621994902 2.560635e-01 0.5481239095 5 98869014 98869277 264 - 0.587 0.750 0.692
ENSG00000153922 E018 0.4876487 0.0743235154 8.474341e-01   5 98869479 98869753 275 - 0.158 0.189 0.305
ENSG00000153922 E019 11.8943650 0.0071292231 1.873369e-01 0.4653782071 5 98869754 98869882 129 - 1.159 1.044 -0.417
ENSG00000153922 E020 10.6877755 0.0014355537 2.431773e-01 0.5330864824 5 98870687 98870803 117 - 1.110 1.011 -0.363
ENSG00000153922 E021 11.8692935 0.0288048535 5.765367e-01 0.8105275035 5 98872051 98872201 151 - 1.080 1.139 0.215
ENSG00000153922 E022 0.6252955 0.1425745975 1.521068e-01 0.4158445904 5 98872202 98872416 215 - 0.086 0.320 2.304
ENSG00000153922 E023 11.8711514 0.0012647970 3.550777e-01 0.6448067833 5 98872417 98872555 139 - 1.072 1.148 0.275
ENSG00000153922 E024 0.1268540 0.0123482147 4.354814e-01   5 98872556 98872557 2 - 0.000 0.104 9.640
ENSG00000153922 E025 10.6987580 0.0013486951 3.414410e-01 0.6329827802 5 98873593 98873723 131 - 1.103 1.022 -0.294
ENSG00000153922 E026 6.3081591 0.0022684612 2.303233e-01 0.5188696262 5 98875072 98875113 42 - 0.917 0.790 -0.492
ENSG00000153922 E027 10.9327375 0.0338084983 4.005991e-01 0.6839550548 5 98876398 98876558 161 - 1.118 1.022 -0.347
ENSG00000153922 E028 12.8733780 0.0025942894 2.491857e-01 0.5401128966 5 98879552 98879728 177 - 1.095 1.188 0.332
ENSG00000153922 E029 8.3690999 0.0223227607 3.022777e-01 0.5954145345 5 98881076 98881171 96 - 1.020 0.907 -0.421
ENSG00000153922 E030 0.0000000       5 98881247 98881278 32 -      
ENSG00000153922 E031 6.8035475 0.0019613909 4.067953e-01 0.6894097010 5 98881279 98881375 97 - 0.929 0.844 -0.323
ENSG00000153922 E032 7.9750396 0.0104997427 2.573004e-01 0.5495653863 5 98881975 98882123 149 - 0.894 1.011 0.438
ENSG00000153922 E033 4.1820929 0.0244916821 2.384745e-01 0.5274507290 5 98883088 98883133 46 - 0.634 0.790 0.646
ENSG00000153922 E034 5.4992294 0.0027400651 8.031771e-01 0.9268841184 5 98883134 98883237 104 - 0.798 0.827 0.112
ENSG00000153922 E035 4.7199499 0.0031396390 1.483221e-01 0.4101099384 5 98885578 98885649 72 - 0.828 0.657 -0.695
ENSG00000153922 E036 1.2674343 0.1757823624 1.466408e-03 0.0200887160 5 98885650 98886231 582 - 0.000 0.570 12.961
ENSG00000153922 E037 0.0000000       5 98886597 98886626 30 -      
ENSG00000153922 E038 7.6944597 0.0018560990 1.096917e-03 0.0160940544 5 98888088 98888240 153 - 1.063 0.729 -1.280
ENSG00000153922 E039 7.9350296 0.0059801068 2.019995e-03 0.0257556577 5 98889076 98889238 163 - 1.072 0.750 -1.223
ENSG00000153922 E040 7.3079321 0.0033433121 8.225686e-01 0.9356232070 5 98892525 98892713 189 - 0.929 0.907 -0.082
ENSG00000153922 E041 5.6013142 0.0025503840 6.359330e-01 0.8447302839 5 98893416 98893606 191 - 0.842 0.790 -0.202
ENSG00000153922 E042 3.8730199 0.0048636042 2.358371e-01 0.5251742832 5 98894597 98894686 90 - 0.750 0.601 -0.628
ENSG00000153922 E043 7.1623660 0.0020846169 3.692324e-01 0.6574723961 5 98896226 98896442 217 - 0.951 0.861 -0.342
ENSG00000153922 E044 5.1316034 0.0393379140 7.894125e-01 0.9191764598 5 98897193 98897320 128 - 0.767 0.809 0.167
ENSG00000153922 E045 8.0104589 0.0189608931 3.041145e-01 0.5975493419 5 98898256 98898434 179 - 1.001 0.892 -0.409
ENSG00000153922 E046 4.1401039 0.0453298561 9.686169e-01 0.9936412263 5 98898664 98898764 101 - 0.715 0.706 -0.035
ENSG00000153922 E047 6.8117857 0.0397224671 6.566878e-01 0.8563711891 5 98899480 98899705 226 - 0.917 0.861 -0.216
ENSG00000153922 E048 8.6382095 0.0017342191 5.033917e-01 0.7628740872 5 98900811 98901082 272 - 1.011 0.949 -0.230
ENSG00000153922 E049 5.8682084 0.0062524782 6.746809e-01 0.8652808511 5 98901186 98901335 150 - 0.813 0.861 0.184
ENSG00000153922 E050 2.2939565 0.0061849205 2.442920e-01 0.5344439658 5 98902900 98902964 65 - 0.587 0.420 -0.811
ENSG00000153922 E051 2.6847220 0.0103330088 9.496150e-01 0.9868878837 5 98903792 98903908 117 - 0.561 0.571 0.042
ENSG00000153922 E052 3.1758626 0.0793019359 9.157019e-01 0.9735683009 5 98904897 98905098 202 - 0.611 0.630 0.081
ENSG00000153922 E053 2.6646140 0.2051858549 6.276853e-01 0.8399859789 5 98926334 98926534 201 - 0.611 0.502 -0.501
ENSG00000153922 E054 4.6401029 0.0044479882 3.283306e-06 0.0001304951 5 98928539 98929043 505 - 0.940 0.320 -2.825

Help

Please Click HERE to learn more details about the results from DEXseq.