ENSG00000154122

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284268 ENSG00000154122 No_inf pgKDN_inf ANKH protein_coding protein_coding 63.47279 33.34618 81.80982 1.841447 5.652473 1.294496 13.073407 9.049654 15.667306 0.2750666 0.1802483 0.7911499 0.2206333 0.273150 0.194600 -0.07855 4.942984e-01 4.664767e-08 FALSE TRUE
ENST00000502585 ENSG00000154122 No_inf pgKDN_inf ANKH protein_coding retained_intron 63.47279 33.34618 81.80982 1.841447 5.652473 1.294496 16.735938 8.800675 21.345626 1.5375560 0.5801573 1.2772917 0.2629667 0.260600 0.263400 0.00280 1.000000e+00 4.664767e-08 FALSE TRUE
ENST00000503939 ENSG00000154122 No_inf pgKDN_inf ANKH protein_coding protein_coding_CDS_not_defined 63.47279 33.34618 81.80982 1.841447 5.652473 1.294496 27.865621 14.975667 34.820118 1.2284477 4.0253095 1.2167520 0.4400167 0.448875 0.421675 -0.02720 8.853363e-01 4.664767e-08 FALSE TRUE
ENST00000513115 ENSG00000154122 No_inf pgKDN_inf ANKH protein_coding retained_intron 63.47279 33.34618 81.80982 1.841447 5.652473 1.294496 4.849416 0.000000 8.480658 0.0000000 1.3385125 9.7297326 0.0610500 0.000000 0.102750 0.10275 4.664767e-08 4.664767e-08 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000154122 E001 312.0595180 0.0000923209 9.665549e-08 5.654032e-06 5 14704800 14711087 6288 - 2.456 2.527 0.235
ENSG00000154122 E002 69.3991421 0.0002417076 8.655143e-01 9.536934e-01 5 14711088 14711310 223 - 1.841 1.832 -0.028
ENSG00000154122 E003 32.9677603 0.0004354219 5.499758e-01 7.946207e-01 5 14712874 14712973 100 - 1.534 1.500 -0.116
ENSG00000154122 E004 34.7719752 0.0004824740 3.237088e-01 6.163604e-01 5 14713544 14713667 124 - 1.524 1.572 0.163
ENSG00000154122 E005 35.4358503 0.0004507291 9.548078e-02 3.217331e-01 5 14716706 14716835 130 - 1.584 1.496 -0.302
ENSG00000154122 E006 0.1186381 0.0117786395 1.000000e+00   5 14716836 14717088 253 - 0.075 0.000 -10.793
ENSG00000154122 E007 0.3625611 0.0164117928 1.000000e+00   5 14741292 14741378 87 - 0.140 0.119 -0.265
ENSG00000154122 E008 0.7256188 0.0398442597 8.406502e-01 9.428146e-01 5 14741457 14741826 370 - 0.245 0.213 -0.265
ENSG00000154122 E009 33.5815613 0.0003954700 7.459229e-01 8.995467e-01 5 14741827 14741922 96 - 1.536 1.517 -0.066
ENSG00000154122 E010 31.0933225 0.0007224781 5.823854e-01 8.139126e-01 5 14745870 14745962 93 - 1.486 1.513 0.094
ENSG00000154122 E011 34.8583904 0.0004415384 5.658353e-01 8.044352e-01 5 14749172 14749306 135 - 1.534 1.561 0.092
ENSG00000154122 E012 44.5926811 0.0057778889 4.248548e-01 7.039994e-01 5 14751069 14751239 171 - 1.666 1.621 -0.154
ENSG00000154122 E013 30.0203434 0.0004668920 2.446907e-01 5.350340e-01 5 14755861 14755944 84 - 1.507 1.440 -0.230
ENSG00000154122 E014 28.8117982 0.0005716477 8.188353e-03 7.021155e-02 5 14758480 14758598 119 - 1.519 1.364 -0.536
ENSG00000154122 E015 0.4697151 0.1686059303 1.774769e-01   5 14768162 14768541 380 - 0.245 0.000 -11.522
ENSG00000154122 E016 0.5906140 0.0144456554 7.523612e-02 2.800404e-01 5 14768616 14768974 359 - 0.290 0.000 -13.051
ENSG00000154122 E017 15.9003363 0.0028254947 4.358747e-02 2.038012e-01 5 14768975 14769006 32 - 1.275 1.114 -0.571
ENSG00000154122 E018 28.0108295 0.0088542016 1.440482e-03 1.979892e-02 5 14769007 14769191 185 - 1.529 1.300 -0.792
ENSG00000154122 E019 0.2536433 0.0160016700 1.103327e-01   5 14788116 14788217 102 - 0.000 0.213 12.148
ENSG00000154122 E020 0.4971544 0.0314729284 1.349335e-01   5 14868415 14868708 294 - 0.075 0.289 2.320
ENSG00000154122 E021 0.4992614 0.0156910586 1.321125e-01   5 14868709 14869030 322 - 0.075 0.289 2.320
ENSG00000154122 E022 0.6244813 0.0150767040 5.442537e-02 2.323390e-01 5 14869031 14870182 1152 - 0.075 0.355 2.735
ENSG00000154122 E023 0.2447669 0.0161052733 6.885475e-01   5 14870183 14871351 1169 - 0.075 0.119 0.735
ENSG00000154122 E024 43.8132737 0.0013469017 7.765399e-03 6.770387e-02 5 14871352 14871778 427 - 1.688 1.557 -0.447

Help

Please Click HERE to learn more details about the results from DEXseq.