ENSG00000154370

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284551 ENSG00000154370 No_inf pgKDN_inf TRIM11 protein_coding protein_coding 36.54516 45.16887 32.7092 1.097787 0.5437768 -0.4655105 20.728774 21.512933 22.0244762 1.2728099 2.5212313 0.0338879 0.58082500 0.476450 0.677425 0.200975 0.45267440 0.03187684 FALSE TRUE
ENST00000475775 ENSG00000154370 No_inf pgKDN_inf TRIM11 protein_coding protein_coding_CDS_not_defined 36.54516 45.16887 32.7092 1.097787 0.5437768 -0.4655105 3.494095 6.698108 0.9810316 0.6789427 0.4026933 -2.7589029 0.08846667 0.147775 0.029600 -0.118175 0.03187684 0.03187684 FALSE FALSE
MSTRG.2804.3 ENSG00000154370 No_inf pgKDN_inf TRIM11 protein_coding   36.54516 45.16887 32.7092 1.097787 0.5437768 -0.4655105 8.790012 11.831979 7.1972321 0.8443293 2.4000688 -0.7163930 0.23634167 0.262500 0.216575 -0.045925 0.85112202 0.03187684 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000154370 E001 0.2447669 0.0161939749 7.683162e-01   1 228393673 228393675 3 - 0.112 0.080 -0.540
ENSG00000154370 E002 1.8497031 0.0089417419 9.640060e-01 9.924265e-01 1 228393676 228393687 12 - 0.443 0.451 0.045
ENSG00000154370 E003 2.9566051 0.0131576097 9.174082e-01 9.740666e-01 1 228393688 228393693 6 - 0.597 0.585 -0.054
ENSG00000154370 E004 213.9860010 0.0001332348 6.159665e-01 8.334366e-01 1 228393694 228394824 1131 - 2.325 2.319 -0.019
ENSG00000154370 E005 91.9860681 0.0029884460 9.413066e-01 9.834269e-01 1 228394825 228395207 383 - 1.958 1.958 0.000
ENSG00000154370 E006 6.7911557 0.0039710388 7.201973e-01 8.872750e-01 1 228395208 228395252 45 - 0.857 0.898 0.155
ENSG00000154370 E007 12.1402220 0.0625973518 3.306618e-01 6.231383e-01 1 228395534 228396612 1079 - 1.031 1.152 0.438
ENSG00000154370 E008 2.7176678 0.0055007866 6.858933e-01 8.702795e-01 1 228396613 228396946 334 - 0.526 0.585 0.268
ENSG00000154370 E009 6.7848324 0.0020096593 9.260721e-01 9.777701e-01 1 228396947 228397047 101 - 0.875 0.886 0.045
ENSG00000154370 E010 0.6168307 0.3628800105 8.881146e-01 9.625733e-01 1 228397048 228397142 95 - 0.201 0.207 0.045
ENSG00000154370 E011 7.7823503 0.0018401481 6.841292e-01 8.692355e-01 1 228397143 228397165 23 - 0.908 0.950 0.161
ENSG00000154370 E012 11.4410698 0.0023177779 1.322987e-08 9.206965e-07 1 228397166 228397689 524 - 0.657 1.231 2.179
ENSG00000154370 E013 23.4913710 0.0006131123 3.407450e-01 6.323722e-01 1 228400964 228401160 197 - 1.411 1.356 -0.190
ENSG00000154370 E014 9.4142047 0.0223018678 1.419418e-01 4.008529e-01 1 228401161 228401194 34 - 1.097 0.940 -0.577
ENSG00000154370 E015 0.1268540 0.0122239003 7.913231e-01   1 228402062 228402065 4 - 0.000 0.080 7.741
ENSG00000154370 E016 12.0339445 0.0226976535 4.886573e-01 7.519163e-01 1 228402066 228402161 96 - 1.145 1.078 -0.244
ENSG00000154370 E017 33.6860083 0.0019838664 4.135830e-08 2.618097e-06 1 228402162 228405904 3743 - 1.311 1.628 1.088
ENSG00000154370 E018 50.9472233 0.0003002388 5.965534e-08 3.667959e-06 1 228406154 228406835 682 - 1.823 1.608 -0.727

Help

Please Click HERE to learn more details about the results from DEXseq.