ENSG00000154447

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000284637 ENSG00000154447 No_inf pgKDN_inf SH3RF1 protein_coding protein_coding 9.558425 9.585695 10.86306 0.3252551 0.4024584 0.180299 9.284068 9.585695 10.1909308 0.3252551 0.39912304 0.08824161 0.9733 1 0.937925 -0.062075 0.007090645 0.007090645 FALSE  
ENST00000510806 ENSG00000154447 No_inf pgKDN_inf SH3RF1 protein_coding protein_coding 9.558425 9.585695 10.86306 0.3252551 0.4024584 0.180299 0.274357 0.000000 0.6721305 0.0000000 0.02413916 6.09197581 0.0267 0 0.062075 0.062075 0.039912398 0.007090645    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000154447 E001 172.3123922 0.0001417047 1.523777e-06 6.703374e-05 4 169094259 169096687 2429 - 2.199 2.269 0.235
ENSG00000154447 E002 18.8813549 0.0305152195 8.389525e-01 9.421964e-01 4 169106847 169107205 359 - 1.305 1.290 -0.052
ENSG00000154447 E003 20.5299237 0.0007573139 1.937667e-01 4.736262e-01 4 169116269 169116630 362 - 1.375 1.290 -0.296
ENSG00000154447 E004 11.8449428 0.0240658432 4.630796e-01 7.331358e-01 4 169117523 169117782 260 - 1.150 1.067 -0.298
ENSG00000154447 E005 8.0307406 0.0019364556 9.791286e-02 3.262996e-01 4 169120819 169120989 171 - 0.864 1.021 0.588
ENSG00000154447 E006 6.6055496 0.0063887486 6.574344e-01 8.566613e-01 4 169122100 169122199 100 - 0.907 0.855 -0.197
ENSG00000154447 E007 4.2388261 0.0035599107 4.410445e-02 2.052930e-01 4 169122200 169122266 67 - 0.833 0.585 -1.028
ENSG00000154447 E008 7.7821804 0.0018332178 8.588715e-02 3.034278e-01 4 169130046 169130156 111 - 1.025 0.855 -0.637
ENSG00000154447 E009 15.3648974 0.0239693047 2.125723e-01 4.977330e-01 4 169136318 169136620 303 - 1.271 1.155 -0.412
ENSG00000154447 E010 5.3260955 0.0032126407 2.223609e-02 1.356039e-01 4 169155480 169155575 96 - 0.920 0.659 -1.041
ENSG00000154447 E011 10.5967987 0.0013841923 9.803089e-02 3.265315e-01 4 169156404 169156679 276 - 1.134 0.990 -0.524
ENSG00000154447 E012 3.6753651 0.0927415162 8.242461e-01 9.361749e-01 4 169268820 169268913 94 - 0.656 0.681 0.104
ENSG00000154447 E013 3.2912811 0.0060339535 4.816279e-01 7.466622e-01 4 169268914 169268975 62 - 0.680 0.585 -0.412
ENSG00000154447 E014 10.6068611 0.0024586427 2.276977e-01 5.161238e-01 4 169268976 169269307 332 - 1.118 1.011 -0.389
ENSG00000154447 E015 0.7158339 0.0132802524 8.109157e-02 2.926028e-01 4 169269699 169269957 259 - 0.355 0.093 -2.405
ENSG00000154447 E016 0.0000000       4 169270757 169270858 102 -      
ENSG00000154447 E017 3.0126517 0.1436753385 2.126901e-01 4.979263e-01 4 169270859 169271173 315 - 0.723 0.462 -1.175

Help

Please Click HERE to learn more details about the results from DEXseq.