ENSG00000154917

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000285208 ENSG00000154917 No_inf pgKDN_inf RAB6B protein_coding protein_coding 0.8062648 0.7270827 1.08552 0.1100151 0.1697535 0.5717172 0.24999202 0.63257631 0.0000000 0.09430917 0.00000000 -6.005796 0.38241667 0.89725 0.000000 -0.897250 0.002089298 0.002089298 FALSE TRUE
ENST00000469959 ENSG00000154917 No_inf pgKDN_inf RAB6B protein_coding protein_coding 0.8062648 0.7270827 1.08552 0.1100151 0.1697535 0.5717172 0.09626881 0.00000000 0.2888064 0.00000000 0.28880643 4.901139 0.06270833 0.00000 0.188125 0.188125 0.850302318 0.002089298 FALSE FALSE
ENST00000486858 ENSG00000154917 No_inf pgKDN_inf RAB6B protein_coding protein_coding 0.8062648 0.7270827 1.08552 0.1100151 0.1697535 0.5717172 0.20578578 0.09450641 0.3368940 0.09450641 0.19484047 1.730904 0.20342500 0.10275 0.322275 0.219525 0.819253674 0.002089298 FALSE TRUE
ENST00000543906 ENSG00000154917 No_inf pgKDN_inf RAB6B protein_coding protein_coding 0.8062648 0.7270827 1.08552 0.1100151 0.1697535 0.5717172 0.25421823 0.00000000 0.4598194 0.00000000 0.08570595 5.554034 0.35145000 0.00000 0.489600 0.489600 0.219872400 0.002089298 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000154917 E001 0.0000000       3 133824235 133824242 8 -      
ENSG00000154917 E002 5.5533956 0.003571755 0.246995530 0.5375678 3 133824243 133827345 3103 - 0.753 0.860 0.422
ENSG00000154917 E003 0.6345490 0.032272448 0.026435634 0.1506770 3 133827346 133827427 82 - 0.000 0.334 11.929
ENSG00000154917 E004 1.9695357 0.013711615 0.755233056 0.9035894 3 133827428 133827747 320 - 0.449 0.489 0.200
ENSG00000154917 E005 0.3631227 0.018221848 0.525980692   3 133827748 133827985 238 - 0.181 0.090 -1.163
ENSG00000154917 E006 2.0940085 0.174859608 0.593829416 0.8211555 3 133827986 133828652 667 - 0.449 0.520 0.354
ENSG00000154917 E007 1.7000973 0.018379759 0.214137589 0.4993586 3 133828653 133828852 200 - 0.523 0.334 -1.011
ENSG00000154917 E008 1.2174550 0.011576927 0.429623360 0.7078018 3 133834575 133834641 67 - 0.407 0.285 -0.748
ENSG00000154917 E009 0.4911106 0.016355952 0.925311648   3 133838166 133838189 24 - 0.181 0.165 -0.163
ENSG00000154917 E010 0.7445367 0.016015276 0.476714292 0.7431204 3 133838190 133838248 59 - 0.181 0.285 0.837
ENSG00000154917 E011 0.4907673 0.025199288 0.926611310   3 133838249 133838259 11 - 0.181 0.165 -0.163
ENSG00000154917 E012 1.0894439 0.015962379 0.250034177 0.5409754 3 133839506 133839617 112 - 0.407 0.229 -1.163
ENSG00000154917 E013 0.7070564 0.015627169 0.006594028 0.0604320 3 133841285 133841325 41 - 0.407 0.000 -12.875
ENSG00000154917 E014 0.9598819 0.146316550 0.169579256 0.4415840 3 133841326 133841390 65 - 0.407 0.165 -1.746
ENSG00000154917 E015 0.9857516 0.079896302 0.576609748 0.8105275 3 133841610 133841663 54 - 0.250 0.334 0.575
ENSG00000154917 E016 1.3491916 0.011699174 0.882214764 0.9604443 3 133864584 133864617 34 - 0.361 0.378 0.100
ENSG00000154917 E017 1.2338867 0.011441371 0.622459333 0.8373273 3 133864618 133864642 25 - 0.309 0.378 0.422
ENSG00000154917 E018 0.0000000       3 133885535 133885570 36 -      
ENSG00000154917 E019 0.0000000       3 133885571 133885665 95 -      
ENSG00000154917 E020 0.0000000       3 133894392 133894719 328 -      
ENSG00000154917 E021 2.0950727 0.008451196 0.590613744 0.8188681 3 133895397 133895882 486 - 0.449 0.520 0.352

Help

Please Click HERE to learn more details about the results from DEXseq.