ENSG00000154920

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338165 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding protein_coding 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 2.0711087 2.6500528 1.0947656 0.41626629 0.6855032 -1.267714600 0.34828333 0.350975 0.275775 -0.075200 0.80595072 0.01693761 FALSE TRUE
ENST00000393271 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding protein_coding 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.4650904 0.4008894 0.3982102 0.40088941 0.3982102 -0.009438098 0.08007500 0.054375 0.076300 0.021925 0.95993335 0.01693761 FALSE TRUE
ENST00000507616 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding retained_intron 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 1.2391184 1.4314976 0.8212368 0.55986741 0.2840338 -0.794236963 0.20758333 0.187450 0.179550 -0.007900 1.00000000 0.01693761   FALSE
ENST00000510007 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding retained_intron 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.4977113 0.9688484 0.1698578 0.09623774 0.1698578 -2.444228595 0.07844167 0.129475 0.043900 -0.085575 0.43776897 0.01693761 TRUE TRUE
ENST00000510246 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding protein_coding 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.4891703 0.9094681 0.5580428 0.90946806 0.3751749 -0.694799747 0.07615833 0.125675 0.102800 -0.022875 0.82150607 0.01693761 FALSE TRUE
ENST00000511648 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding protein_coding 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.3004643 0.0000000 0.9013928 0.00000000 0.9013928 6.510001015 0.05445000 0.000000 0.163350 0.163350 0.81924174 0.01693761 FALSE TRUE
ENST00000513077 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding retained_intron 5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.2942283 0.0000000 0.5684613 0.00000000 0.4256537 5.854148428 0.05570000 0.000000 0.114625 0.114625 0.42443825 0.01693761 FALSE TRUE
MSTRG.12919.3 ENSG00000154920 No_inf pgKDN_inf EME1 protein_coding   5.994016 7.502607 4.694416 0.1191775 0.3987326 -0.6752979 0.4296625 1.1418509 0.0000000 0.04343352 0.0000000 -6.847810128 0.05969167 0.152050 0.000000 -0.152050 0.01693761 0.01693761 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000154920 E001 0.0000000       17 50373220 50373228 9 +      
ENSG00000154920 E002 0.0000000       17 50373229 50373241 13 +      
ENSG00000154920 E003 0.0000000       17 50373242 50373243 2 +      
ENSG00000154920 E004 0.0000000       17 50373244 50373253 10 +      
ENSG00000154920 E005 0.0000000       17 50373254 50373277 24 +      
ENSG00000154920 E006 3.6001286 0.005202925 0.3977290047 0.68187973 17 50375185 50375512 328 + 0.585 0.680 0.413
ENSG00000154920 E007 3.5379001 0.004493089 0.0670022870 0.26091706 17 50375513 50375687 175 + 0.782 0.539 -1.038
ENSG00000154920 E008 0.9455859 0.012800783 0.0002130097 0.00440171 17 50375688 50375796 109 + 0.548 0.000 -13.040
ENSG00000154920 E009 1.3873011 0.010567829 0.0275651493 0.15484832 17 50375797 50375983 187 + 0.119 0.462 2.583
ENSG00000154920 E010 1.9696955 0.008066835 0.6754198472 0.86552210 17 50376066 50376108 43 + 0.507 0.432 -0.376
ENSG00000154920 E011 1.9494586 0.007714399 0.1534344442 0.41805170 17 50376109 50376193 85 + 0.585 0.367 -1.101
ENSG00000154920 E012 0.3706447 0.072496324 1.0000000000   17 50378595 50378599 5 + 0.119 0.140 0.261
ENSG00000154920 E013 1.4777311 0.015842701 0.8379819282 0.94200442 17 50378600 50378681 82 + 0.412 0.367 -0.253
ENSG00000154920 E014 4.4567191 0.006124799 0.5074641456 0.76588653 17 50378774 50378882 109 + 0.681 0.744 0.261
ENSG00000154920 E015 2.2563551 0.007009071 0.0421168334 0.19971244 17 50378883 50378895 13 + 0.290 0.585 1.583
ENSG00000154920 E016 1.5069159 0.009599357 0.0991974468 0.32891130 17 50378896 50379067 172 + 0.213 0.462 1.583
ENSG00000154920 E017 0.4887509 0.016509981 0.6420597434   17 50379068 50379106 39 + 0.213 0.140 -0.739
ENSG00000154920 E018 5.0499778 0.018967354 0.6915607704 0.87362717 17 50379107 50379224 118 + 0.804 0.744 -0.241
ENSG00000154920 E019 4.4282984 0.003264930 0.4594537185 0.73108650 17 50379452 50379567 116 + 0.782 0.680 -0.417
ENSG00000154920 E020 1.6246102 0.008973515 0.2364509222 0.52543134 17 50379568 50379758 191 + 0.290 0.462 0.998
ENSG00000154920 E021 4.5033414 0.015821597 0.0167137493 0.11272219 17 50379759 50380311 553 + 0.507 0.813 1.312
ENSG00000154920 E022 8.3845632 0.001840001 0.6377153899 0.84546638 17 50380312 50380501 190 + 0.994 0.933 -0.224
ENSG00000154920 E023 11.3281572 0.044529564 0.4677430646 0.73604081 17 50380763 50381483 721 + 1.125 1.043 -0.296

Help

Please Click HERE to learn more details about the results from DEXseq.