ENSG00000155508

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000285896 ENSG00000155508 No_inf pgKDN_inf CNOT8 protein_coding protein_coding 47.70469 43.84131 57.05005 1.185869 1.642536 0.379861 21.850975 17.205736 36.908647 6.636024 7.057757 1.1006219 0.43372500 0.390850 0.638375 0.247525 0.807934568 0.004925661 FALSE TRUE
ENST00000403027 ENSG00000155508 No_inf pgKDN_inf CNOT8 protein_coding protein_coding 47.70469 43.84131 57.05005 1.185869 1.642536 0.379861 3.912655 5.269321 3.501750 1.658546 1.741408 -0.5881625 0.08473333 0.120900 0.064050 -0.056850 0.763783574 0.004925661 FALSE TRUE
ENST00000520671 ENSG00000155508 No_inf pgKDN_inf CNOT8 protein_coding protein_coding 47.70469 43.84131 57.05005 1.185869 1.642536 0.379861 3.832120 9.311618 0.000000 3.732566 0.000000 -9.8644366 0.08770833 0.208425 0.000000 -0.208425 0.005758138 0.004925661 FALSE TRUE
ENST00000521450 ENSG00000155508 No_inf pgKDN_inf CNOT8 protein_coding protein_coding 47.70469 43.84131 57.05005 1.185869 1.642536 0.379861 3.709569 2.696907 2.381160 2.696907 2.381160 -0.1789345 0.08174167 0.066300 0.043700 -0.022600 1.000000000 0.004925661 FALSE TRUE
MSTRG.23820.2 ENSG00000155508 No_inf pgKDN_inf CNOT8 protein_coding   47.70469 43.84131 57.05005 1.185869 1.642536 0.379861 5.522633 3.395257 6.226847 2.123709 6.226847 0.8730533 0.11904167 0.076475 0.115300 0.038825 0.839167787 0.004925661 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000155508 E001 0.2452102 1.678313e-02 0.9369765705   5 154857553 154857820 268 + 0.091 0.100 0.150
ENSG00000155508 E002 0.0000000       5 154857821 154857880 60 +      
ENSG00000155508 E003 0.0000000       5 154857881 154857893 13 +      
ENSG00000155508 E004 0.0000000       5 154858219 154858240 22 +      
ENSG00000155508 E005 0.0000000       5 154858241 154858248 8 +      
ENSG00000155508 E006 0.0000000       5 154858249 154858251 3 +      
ENSG00000155508 E007 0.2459655 1.662235e-02 0.9375094425   5 154858252 154858261 10 + 0.091 0.100 0.150
ENSG00000155508 E008 1.2442065 7.246351e-02 0.1854257597 0.463124391 5 154858262 154858481 220 + 0.230 0.448 1.372
ENSG00000155508 E009 0.1272623 1.236663e-02 0.4861658874   5 154858482 154858514 33 + 0.000 0.100 12.087
ENSG00000155508 E010 0.1272623 1.236663e-02 0.4861658874   5 154858515 154858516 2 + 0.000 0.100 12.087
ENSG00000155508 E011 0.1268540 1.230729e-02 0.4862014887   5 154858517 154858525 9 + 0.000 0.100 12.088
ENSG00000155508 E012 0.1271363 1.236736e-02 0.4861545620   5 154858526 154858536 11 + 0.000 0.100 12.087
ENSG00000155508 E013 0.1271363 1.236736e-02 0.4861545620   5 154858537 154858538 2 + 0.000 0.100 12.087
ENSG00000155508 E014 0.1271363 1.236736e-02 0.4861545620   5 154858539 154858543 5 + 0.000 0.100 12.087
ENSG00000155508 E015 0.1271363 1.236736e-02 0.4861545620   5 154858544 154858624 81 + 0.000 0.100 12.087
ENSG00000155508 E016 0.0000000       5 154858625 154858626 2 +      
ENSG00000155508 E017 0.0000000       5 154858627 154858634 8 +      
ENSG00000155508 E018 0.0000000       5 154858635 154858638 4 +      
ENSG00000155508 E019 0.0000000       5 154858639 154858651 13 +      
ENSG00000155508 E020 0.0000000       5 154858652 154858653 2 +      
ENSG00000155508 E021 0.0000000       5 154858654 154858661 8 +      
ENSG00000155508 E022 0.0000000       5 154858662 154858688 27 +      
ENSG00000155508 E023 0.0000000       5 154858689 154858768 80 +      
ENSG00000155508 E024 0.4996734 2.608869e-02 0.2763477652   5 154858769 154858797 29 + 0.091 0.249 1.735
ENSG00000155508 E025 0.4996734 2.608869e-02 0.2763477652   5 154858798 154858801 4 + 0.091 0.249 1.735
ENSG00000155508 E026 0.8550537 1.600721e-02 0.8082533477 0.929176938 5 154858802 154858816 15 + 0.285 0.249 -0.265
ENSG00000155508 E027 0.0000000       5 154858817 154858833 17 +      
ENSG00000155508 E028 1.7130660 2.469756e-02 0.8539088536 0.948420627 5 154859353 154859404 52 + 0.419 0.448 0.150
ENSG00000155508 E029 2.2382002 7.780596e-03 0.0357122197 0.181172774 5 154859405 154859496 92 + 0.335 0.639 1.528
ENSG00000155508 E030 0.4900381 1.593429e-02 0.9190220678   5 154859667 154859694 28 + 0.166 0.181 0.150
ENSG00000155508 E031 1.3636298 1.055696e-02 0.2874862272 0.580917994 5 154859695 154859837 143 + 0.285 0.448 0.957
ENSG00000155508 E032 0.4730484 1.616141e-02 0.0569168471   5 154859838 154859873 36 + 0.285 0.000 -14.658
ENSG00000155508 E033 2.2167024 6.410809e-03 0.4976656329 0.758265954 5 154863207 154863211 5 + 0.456 0.554 0.472
ENSG00000155508 E034 36.7737769 3.816061e-04 0.0713456573 0.270612901 5 154863212 154863395 184 + 1.617 1.531 -0.293
ENSG00000155508 E035 61.0918786 4.504664e-04 0.0069887435 0.062998780 5 154865192 154865385 194 + 1.839 1.739 -0.338
ENSG00000155508 E036 0.7451311 2.597975e-02 0.3531493631 0.642971295 5 154867692 154867792 101 + 0.166 0.308 1.150
ENSG00000155508 E037 0.3628435 1.671791e-02 0.6481863491   5 154870444 154870660 217 + 0.166 0.100 -0.850
ENSG00000155508 E038 49.8972579 2.979643e-04 0.0159929691 0.109647953 5 154870661 154870822 162 + 1.752 1.654 -0.333
ENSG00000155508 E039 48.0123019 3.134905e-04 0.0967583551 0.323933279 5 154871730 154871874 145 + 1.723 1.654 -0.233
ENSG00000155508 E040 38.8925743 4.129953e-04 0.8133491265 0.931619593 5 154872541 154872651 111 + 1.595 1.607 0.041
ENSG00000155508 E041 370.9047597 9.467126e-05 0.0001405622 0.003136566 5 154875290 154876792 1503 + 2.550 2.590 0.132

Help

Please Click HERE to learn more details about the results from DEXseq.