ENSG00000156471

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000517309 ENSG00000156471 No_inf pgKDN_inf PTDSS1 protein_coding protein_coding 153.9375 48.22172 212.1673 0.2426076 5.12529 2.137216 109.07378 46.96235 138.57302 0.1472577 1.218297 1.560867 0.7778000 0.973925 0.654400 -0.319525 4.606025e-38 4.606025e-38 FALSE TRUE
ENST00000517557 ENSG00000156471 No_inf pgKDN_inf PTDSS1 protein_coding retained_intron 153.9375 48.22172 212.1673 0.2426076 5.12529 2.137216 12.80359 0.00000 26.19354 0.0000000 2.428540 11.355546 0.0610000 0.000000 0.122975 0.122975 5.075416e-17 4.606025e-38 FALSE TRUE
ENST00000518776 ENSG00000156471 No_inf pgKDN_inf PTDSS1 protein_coding protein_coding_CDS_not_defined 153.9375 48.22172 212.1673 0.2426076 5.12529 2.137216 30.72635 0.00000 46.35264 0.0000000 3.610126 12.178747 0.1480917 0.000000 0.217650 0.217650 3.477237e-30 4.606025e-38 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000156471 E001 0.8610948 1.601125e-02 9.603020e-02 3.227581e-01 8 96261902 96261911 10 + 0.160 0.418 1.865
ENSG00000156471 E002 0.9961610 9.890534e-02 9.442216e-03 7.746524e-02 8 96261912 96261912 1 + 0.113 0.535 3.035
ENSG00000156471 E003 20.5890719 6.452571e-04 9.815492e-01 9.982180e-01 8 96261913 96261966 54 + 1.290 1.293 0.008
ENSG00000156471 E004 167.6717582 1.097654e-04 9.377812e-06 3.231840e-04 8 96261967 96262219 253 + 2.212 2.093 -0.397
ENSG00000156471 E005 112.4172195 3.998741e-04 2.195267e-01 5.062404e-01 8 96273299 96273390 92 + 2.020 1.981 -0.133
ENSG00000156471 E006 0.0000000       8 96283597 96283763 167 +      
ENSG00000156471 E007 87.5559323 1.795486e-04 2.222909e-03 2.766914e-02 8 96284109 96284153 45 + 1.931 1.818 -0.383
ENSG00000156471 E008 139.5043380 1.285525e-04 4.765804e-03 4.787463e-02 8 96287022 96287146 125 + 2.124 2.042 -0.274
ENSG00000156471 E009 0.4804091 1.530201e-02 1.000000e+00   8 96287147 96287388 242 + 0.160 0.148 -0.135
ENSG00000156471 E010 112.6738392 1.653229e-04 4.450434e-03 4.565039e-02 8 96295098 96295191 94 + 2.035 1.942 -0.310
ENSG00000156471 E011 88.0639754 2.098943e-04 5.277518e-03 5.162090e-02 8 96295192 96295256 65 + 1.931 1.828 -0.347
ENSG00000156471 E012 175.7780675 3.006286e-04 1.031127e-02 8.191603e-02 8 96299694 96299845 152 + 2.220 2.153 -0.224
ENSG00000156471 E013 226.1302630 8.380883e-05 2.344463e-01 5.235282e-01 8 96304040 96304181 142 + 2.318 2.292 -0.086
ENSG00000156471 E014 228.9204814 8.530373e-05 3.554844e-01 6.453008e-01 8 96306444 96306556 113 + 2.322 2.302 -0.066
ENSG00000156471 E015 176.0588671 1.067426e-04 2.140875e-01 4.992907e-01 8 96309557 96309622 66 + 2.211 2.180 -0.103
ENSG00000156471 E016 150.7702107 1.126829e-04 7.385190e-01 8.963339e-01 8 96320246 96320345 100 + 2.133 2.143 0.033
ENSG00000156471 E017 119.1337691 2.200223e-04 4.875359e-01 7.509142e-01 8 96330213 96330281 69 + 2.028 2.050 0.074
ENSG00000156471 E018 11.5583771 4.710327e-03 8.478821e-08 5.008727e-06 8 96330317 96331025 709 + 0.867 1.335 1.696
ENSG00000156471 E019 121.6020127 1.291389e-04 3.591069e-02 1.817898e-01 8 96331026 96331095 70 + 2.025 2.088 0.212
ENSG00000156471 E020 105.3352142 1.666226e-04 4.212287e-02 1.997235e-01 8 96333457 96333486 30 + 1.962 2.028 0.221
ENSG00000156471 E021 230.3889666 8.407196e-05 5.629146e-02 2.365426e-01 8 96333487 96333677 191 + 2.307 2.349 0.139
ENSG00000156471 E022 1020.1934083 5.697679e-05 1.243041e-08 8.706778e-07 8 96333678 96336995 3318 + 2.948 3.000 0.172

Help

Please Click HERE to learn more details about the results from DEXseq.