ENSG00000156958

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396509 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding protein_coding 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 1.5367612 2.5516032 0.00000000 1.4774175 0.00000000 -8.0009032 0.18932500 0.297950 0.000000 -0.297950 0.623372482 0.006149669 FALSE TRUE
ENST00000559040 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding protein_coding_CDS_not_defined 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 0.6981119 1.0319729 0.61061592 0.7020712 0.35349700 -0.7475451 0.05872500 0.071350 0.063025 -0.008325 1.000000000 0.006149669   FALSE
ENST00000559208 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding nonsense_mediated_decay 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 0.6179104 0.7540532 0.39690557 0.5849769 0.28607876 -0.9089790 0.06007500 0.049250 0.044000 -0.005250 0.995558883 0.006149669 FALSE FALSE
ENST00000559454 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding protein_coding 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 3.3422224 1.1211356 6.21736303 1.1211356 0.36225877 2.4608495 0.36125833 0.109225 0.702925 0.593700 0.006149669 0.006149669 FALSE TRUE
ENST00000559963 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding nonsense_mediated_decay 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 0.5127681 0.6260544 0.33804491 0.4148075 0.33804491 -0.8698767 0.05077500 0.063050 0.033350 -0.029700 0.862400354 0.006149669 FALSE FALSE
ENST00000560119 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding nonsense_mediated_decay 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 0.3659384 0.9523222 0.06011884 0.3465420 0.06011884 -3.7786461 0.03673333 0.095850 0.006500 -0.089350 0.294677395 0.006149669 TRUE TRUE
ENST00000561014 ENSG00000156958 No_inf pgKDN_inf GALK2 protein_coding protein_coding_CDS_not_defined 9.732489 11.14452 8.900217 2.058332 0.5018524 -0.3240958 0.7020419 1.6684800 0.00000000 0.9022024 0.00000000 -7.3910115 0.05525000 0.125250 0.000000 -0.125250 0.106762148 0.006149669 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000156958 E001 0.0000000       15 49155656 49155758 103 +      
ENSG00000156958 E002 0.0000000       15 49155759 49155764 6 +      
ENSG00000156958 E003 0.0000000       15 49155765 49155770 6 +      
ENSG00000156958 E004 0.0000000       15 49155771 49155774 4 +      
ENSG00000156958 E005 0.0000000       15 49155775 49155793 19 +      
ENSG00000156958 E006 0.0000000       15 49155794 49155800 7 +      
ENSG00000156958 E007 1.7236103 0.008264892 0.785189326 0.91717419 15 49155801 49156016 216 + 0.441 0.421 -0.107
ENSG00000156958 E008 0.1268540 0.012322336 0.844999842   15 49158845 49158968 124 + 0.000 0.081 11.693
ENSG00000156958 E009 0.3711203 0.017000315 0.897294449   15 49161740 49161763 24 + 0.112 0.149 0.478
ENSG00000156958 E010 0.4881243 0.038996321 0.667056121   15 49161764 49161861 98 + 0.200 0.149 -0.522
ENSG00000156958 E011 0.2539903 0.016108915 0.430436790   15 49170204 49170216 13 + 0.000 0.149 12.693
ENSG00000156958 E012 0.2539903 0.016108915 0.430436790   15 49170217 49170223 7 + 0.000 0.149 12.693
ENSG00000156958 E013 0.6356513 0.015703278 0.062123758 0.25034700 15 49170224 49170246 23 + 0.000 0.306 14.015
ENSG00000156958 E014 0.5087973 0.086909754 0.126364882 0.37686914 15 49170247 49170248 2 + 0.000 0.259 13.693
ENSG00000156958 E015 0.5087973 0.086909754 0.126364882 0.37686914 15 49170249 49170259 11 + 0.000 0.259 13.693
ENSG00000156958 E016 0.6359336 0.227363035 0.102728691 0.33504077 15 49170260 49170281 22 + 0.000 0.306 14.016
ENSG00000156958 E017 0.6359336 0.227363035 0.102728691 0.33504077 15 49170282 49170282 1 + 0.000 0.306 14.016
ENSG00000156958 E018 0.9991214 0.019482443 0.396675365 0.68131609 15 49170283 49170311 29 + 0.200 0.347 1.063
ENSG00000156958 E019 1.1160926 0.010802380 0.711928081 0.88356603 15 49170312 49170358 47 + 0.274 0.347 0.478
ENSG00000156958 E020 1.2238091 0.012752645 0.497593566 0.75819899 15 49170359 49170375 17 + 0.392 0.306 -0.522
ENSG00000156958 E021 0.1265070 0.012509479 0.844681525   15 49170478 49170577 100 + 0.000 0.081 11.693
ENSG00000156958 E022 0.0000000       15 49185614 49185674 61 +      
ENSG00000156958 E023 0.0000000       15 49193911 49194210 300 +      
ENSG00000156958 E024 0.0000000       15 49195085 49195214 130 +      
ENSG00000156958 E025 4.7076324 0.058895958 0.391586215 0.67666773 15 49201162 49201250 89 + 0.655 0.800 0.594
ENSG00000156958 E026 0.0000000       15 49217173 49217189 17 +      
ENSG00000156958 E027 8.2224373 0.009911470 0.257648267 0.54990556 15 49217190 49217313 124 + 1.004 0.922 -0.307
ENSG00000156958 E028 0.0000000       15 49223129 49223149 21 +      
ENSG00000156958 E029 0.4981926 0.320121613 0.749980848   15 49225205 49225349 145 + 0.112 0.208 1.063
ENSG00000156958 E030 0.0000000       15 49226675 49226695 21 +      
ENSG00000156958 E031 0.0000000       15 49235625 49235739 115 +      
ENSG00000156958 E032 6.8567608 0.012142046 0.112828113 0.35338394 15 49235851 49235941 91 + 0.964 0.827 -0.522
ENSG00000156958 E033 0.0000000       15 49239220 49239220 1 +      
ENSG00000156958 E034 7.2823972 0.001973091 0.957370742 0.98981997 15 49239221 49239367 147 + 0.889 0.922 0.124
ENSG00000156958 E035 5.5338216 0.002951857 0.477216289 0.74355843 15 49281987 49282085 99 + 0.837 0.786 -0.200
ENSG00000156958 E036 8.8718836 0.001743882 0.670118425 0.86299349 15 49283566 49283705 140 + 0.991 0.981 -0.037
ENSG00000156958 E037 4.4618973 0.003901737 0.456422149 0.72872226 15 49283706 49283718 13 + 0.655 0.771 0.478
ENSG00000156958 E038 5.6802003 0.002829937 0.980463571 0.99781716 15 49292327 49292380 54 + 0.798 0.827 0.115
ENSG00000156958 E039 7.0994567 0.005048792 0.054190333 0.23171036 15 49292381 49292470 90 + 0.991 0.827 -0.622
ENSG00000156958 E040 4.8619475 0.002901801 0.007467587 0.06600407 15 49292471 49292537 67 + 0.905 0.630 -1.107
ENSG00000156958 E041 1.1249726 0.087137391 0.324488858 0.61688646 15 49318111 49318192 82 + 0.201 0.386 1.284
ENSG00000156958 E042 1.3723492 0.121752730 0.465189781 0.73434864 15 49318972 49319116 145 + 0.274 0.421 0.893
ENSG00000156958 E043 7.2940625 0.002089084 0.740086259 0.89686991 15 49319604 49319681 78 + 0.872 0.932 0.228
ENSG00000156958 E044 5.5693521 0.002785322 0.595026452 0.82194849 15 49319682 49319805 124 + 0.755 0.840 0.336
ENSG00000156958 E045 0.0000000       15 49327952 49328130 179 +      
ENSG00000156958 E046 0.0000000       15 49328131 49328665 535 +      
ENSG00000156958 E047 4.3766388 0.073784009 0.042539382 0.20100920 15 49328666 49331882 3217 + 0.485 0.827 1.478
ENSG00000156958 E048 0.1271363 0.012548786 0.844701003   15 49367491 49367869 379 + 0.000 0.081 11.693

Help

Please Click HERE to learn more details about the results from DEXseq.