ENSG00000156976

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323963 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding protein_coding 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 14.638807 17.770795 12.656804 12.061550 8.244055 -0.48926725 0.07429167 0.081650 0.066700 -0.014950 1.000000000 0.001394795 FALSE TRUE
ENST00000363450 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding snoRNA 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 15.746680 28.441667 0.000000 17.080781 0.000000 -11.47429746 0.06160833 0.110625 0.000000 -0.110625 0.789216611 0.001394795   FALSE
ENST00000425053 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding nonsense_mediated_decay 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 19.204589 13.632221 22.870874 1.026136 2.801894 0.74606364 0.09808333 0.062100 0.109775 0.047675 0.534957770 0.001394795 TRUE TRUE
ENST00000426808 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding nonsense_mediated_decay 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 31.056607 38.924114 24.571890 10.361969 6.786577 -0.66343895 0.14985000 0.173550 0.106975 -0.066575 0.777011789 0.001394795 FALSE TRUE
ENST00000440191 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding protein_coding 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 6.292537 0.000000 18.877611 0.000000 7.746411 10.88322452 0.02551667 0.000000 0.076550 0.076550 0.001394795 0.001394795 FALSE TRUE
ENST00000496382 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding retained_intron 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 40.351411 45.816472 47.976507 1.603945 2.646796 0.06644758 0.19336667 0.205050 0.229425 0.024375 0.931478870 0.001394795   FALSE
ENST00000584302 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding snoRNA 215.902 226.826 233.2051 17.72465 46.51078 0.04001215 14.213488 0.000000 42.640463 0.000000 42.640463 12.05834569 0.03815000 0.000000 0.114450 0.114450 0.557881422 0.001394795   FALSE
MSTRG.21253.23 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding   215.902 226.826 233.2051 17.72465 46.51078 0.04001215 7.284984 1.764623 12.792164 1.764623 1.437932 2.85080285 0.03604167 0.007450 0.061475 0.054025 0.013143474 0.001394795 TRUE TRUE
MSTRG.21253.24 ENSG00000156976 No_inf pgKDN_inf EIF4A2 protein_coding   215.902 226.826 233.2051 17.72465 46.51078 0.04001215 18.753813 28.649164 4.098967 2.962177 4.098967 -2.80214905 0.09555000 0.128100 0.022300 -0.105800 0.034861775 0.001394795 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000156976 E001 0.0000000       3 186783205 186783304 100 +      
ENSG00000156976 E002 0.0000000       3 186783305 186783350 46 +      
ENSG00000156976 E003 0.0000000       3 186783351 186783447 97 +      
ENSG00000156976 E004 0.0000000       3 186783448 186783547 100 +      
ENSG00000156976 E005 0.0000000       3 186783548 186783571 24 +      
ENSG00000156976 E006 0.0000000       3 186783572 186783574 3 +      
ENSG00000156976 E007 0.0000000       3 186783575 186783576 2 +      
ENSG00000156976 E008 0.0000000       3 186783577 186783577 1 +      
ENSG00000156976 E009 0.0000000       3 186783578 186783583 6 +      
ENSG00000156976 E010 0.0000000       3 186783584 186783584 1 +      
ENSG00000156976 E011 0.0000000       3 186783585 186783586 2 +      
ENSG00000156976 E012 0.0000000       3 186783587 186783587 1 +      
ENSG00000156976 E013 0.0000000       3 186783588 186783589 2 +      
ENSG00000156976 E014 0.0000000       3 186783590 186783592 3 +      
ENSG00000156976 E015 0.0000000       3 186783593 186783596 4 +      
ENSG00000156976 E016 0.0000000       3 186783597 186783639 43 +      
ENSG00000156976 E017 0.6079882 2.290276e-01 4.880166e-01 7.514828e-01 3 186784203 186784428 226 + 0.267 0.153 -1.002
ENSG00000156976 E018 0.4811992 1.532541e-02 2.003771e-01   3 186784429 186784431 3 + 0.267 0.083 -2.002
ENSG00000156976 E019 23.5400184 9.991152e-03 1.519956e-01 4.156930e-01 3 186784432 186784477 46 + 1.441 1.338 -0.357
ENSG00000156976 E020 2.3300277 7.759886e-02 7.176483e-01 8.864632e-01 3 186784478 186784563 86 + 0.550 0.494 -0.265
ENSG00000156976 E021 94.2663390 3.580528e-03 7.203612e-01 8.874363e-01 3 186784564 186784696 133 + 1.980 1.966 -0.046
ENSG00000156976 E022 4.3002250 3.284575e-03 7.371108e-01 8.958141e-01 3 186784697 186784795 99 + 0.742 0.701 -0.169
ENSG00000156976 E023 4.7672621 1.144916e-02 3.174669e-01 6.102653e-01 3 186784796 186784961 166 + 0.823 0.701 -0.491
ENSG00000156976 E024 67.2580659 2.258801e-04 4.095538e-01 6.918066e-01 3 186784962 186785060 99 + 1.845 1.814 -0.105
ENSG00000156976 E025 51.2534057 2.869670e-04 3.187893e-02 1.687134e-01 3 186785061 186785101 41 + 1.762 1.672 -0.307
ENSG00000156976 E026 18.6073721 6.292861e-03 6.889444e-01 8.719150e-01 3 186785102 186785882 781 + 1.268 1.298 0.104
ENSG00000156976 E027 86.4425103 1.650854e-03 9.522271e-02 3.212449e-01 3 186785883 186785961 79 + 1.969 1.909 -0.204
ENSG00000156976 E028 54.1472851 2.912135e-04 1.808778e-01 4.566097e-01 3 186785962 186785994 33 + 1.767 1.711 -0.188
ENSG00000156976 E029 74.5732205 2.284527e-04 1.943717e-01 4.742225e-01 3 186785995 186786051 57 + 1.898 1.852 -0.155
ENSG00000156976 E030 0.4893505 1.586009e-02 7.759251e-01   3 186786052 186786075 24 + 0.195 0.153 -0.417
ENSG00000156976 E031 1.4605878 8.639536e-03 2.880431e-01 5.816075e-01 3 186786076 186786163 88 + 0.474 0.314 -0.903
ENSG00000156976 E032 104.8310790 6.557003e-04 2.192094e-01 5.058549e-01 3 186786164 186786273 110 + 2.040 2.001 -0.129
ENSG00000156976 E033 1.1242438 1.085501e-02 1.984748e-01 4.798720e-01 3 186786274 186786322 49 + 0.195 0.395 1.390
ENSG00000156976 E034 1.5891102 2.810206e-02 4.497315e-01 7.233211e-01 3 186786323 186786490 168 + 0.474 0.356 -0.640
ENSG00000156976 E035 0.6171771 2.136190e-02 8.985272e-01 9.666520e-01 3 186786491 186786501 11 + 0.195 0.214 0.168
ENSG00000156976 E036 128.2181105 3.530576e-04 2.665095e-01 5.599940e-01 3 186786502 186786639 138 + 2.122 2.091 -0.103
ENSG00000156976 E037 46.0682656 2.281144e-03 6.765812e-01 8.659598e-01 3 186786640 186786645 6 + 1.654 1.674 0.066
ENSG00000156976 E038 1.3699595 3.641875e-02 3.094182e-01 6.027860e-01 3 186786646 186786671 26 + 0.267 0.430 0.998
ENSG00000156976 E039 0.7429934 1.386030e-02 6.365664e-01 8.448856e-01 3 186786672 186786674 3 + 0.195 0.267 0.583
ENSG00000156976 E040 9.8650135 1.427779e-03 7.737388e-01 9.129831e-01 3 186786675 186787126 452 + 1.014 1.040 0.093
ENSG00000156976 E041 144.5951469 1.705688e-04 2.854544e-01 5.791297e-01 3 186787127 186787264 138 + 2.172 2.145 -0.092
ENSG00000156976 E042 4.2066684 3.476584e-03 3.745146e-01 6.621344e-01 3 186787265 186787299 35 + 0.643 0.753 0.457
ENSG00000156976 E043 2.9748315 5.052665e-03 3.465571e-01 6.372510e-01 3 186787300 186787313 14 + 0.514 0.642 0.583
ENSG00000156976 E044 5.8480506 2.407319e-03 3.304311e-02 1.726385e-01 3 186787314 186787406 93 + 0.670 0.914 0.970
ENSG00000156976 E045 5.5919901 2.491509e-03 5.580325e-02 2.353897e-01 3 186787407 186787478 72 + 0.670 0.891 0.882
ENSG00000156976 E046 4.5945064 1.174050e-02 1.168735e-01 3.607759e-01 3 186787479 186787494 16 + 0.614 0.813 0.824
ENSG00000156976 E047 111.4927169 1.484484e-04 8.566408e-01 9.496437e-01 3 186787495 186787584 90 + 2.048 2.042 -0.020
ENSG00000156976 E048 2.7277003 1.282704e-02 3.047463e-01 5.980835e-01 3 186787585 186787611 27 + 0.474 0.621 0.682
ENSG00000156976 E049 8.5447328 2.023909e-03 1.770814e-01 4.514851e-01 3 186787612 186787775 164 + 0.891 1.023 0.490
ENSG00000156976 E050 3.4768314 4.574782e-03 2.516168e-01 5.428172e-01 3 186787776 186787802 27 + 0.550 0.701 0.661
ENSG00000156976 E051 120.6017350 1.425238e-04 2.027223e-01 4.852273e-01 3 186787803 186787882 80 + 2.098 2.063 -0.119
ENSG00000156976 E052 79.4900391 1.876061e-04 9.172304e-11 9.229460e-09 3 186787883 186788309 427 + 1.749 1.979 0.773
ENSG00000156976 E053 81.3882473 1.915682e-04 9.801678e-01 9.977610e-01 3 186788310 186788416 107 + 1.909 1.909 0.000
ENSG00000156976 E054 25.8800870 1.051601e-03 1.475198e-02 1.038686e-01 3 186788417 186788420 4 + 1.330 1.477 0.511
ENSG00000156976 E055 195.8885814 1.077784e-04 1.550347e-13 2.247753e-11 3 186788421 186789124 704 + 2.185 2.346 0.538
ENSG00000156976 E056 568.8956793 6.826803e-05 1.667108e-03 2.217357e-02 3 186789125 186789897 773 + 2.770 2.733 -0.121

Help

Please Click HERE to learn more details about the results from DEXseq.