ENSG00000157168

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000405005 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 11.7274537 1.86381532 14.478584 0.40561313 0.4681591 2.950866 0.30645000 0.254525 0.341650 0.087125 0.793247763 0.002977509 FALSE TRUE
ENST00000521670 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 4.6468936 0.22083262 6.872124 0.22083262 0.4430547 4.897935 0.10562500 0.038900 0.160325 0.121425 0.165429397 0.002977509 FALSE TRUE
ENST00000522402 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 2.4698014 0.66965434 4.512373 0.66965434 2.8559911 2.734207 0.07520000 0.088050 0.097100 0.009050 0.936466142 0.002977509 FALSE FALSE
ENST00000523079 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 4.1151517 0.80323624 5.608470 0.26968048 0.3939403 2.788431 0.11483333 0.109025 0.132575 0.023550 0.852204265 0.002977509 FALSE TRUE
ENST00000539990 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 0.1755543 0.52666300 0.000000 0.52666300 0.0000000 -5.745945 0.03150833 0.094525 0.000000 -0.094525 0.630843613 0.002977509 FALSE TRUE
ENST00000631040 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding_CDS_not_defined 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 2.2176894 1.36796431 0.000000 0.88303086 0.0000000 -7.106395 0.08580833 0.168375 0.000000 -0.168375 0.150039827 0.002977509 FALSE FALSE
ENST00000650919 ENSG00000157168 No_inf pgKDN_inf NRG1 protein_coding protein_coding 36.13199 7.271201 42.85441 1.090789 2.046719 2.557532 5.0209979 0.07104994 7.145428 0.07104994 0.8091072 6.464083 0.10370000 0.009350 0.165625 0.156275 0.002977509 0.002977509 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157168 E001 0.0000000       8 31639222 31639244 23 +      
ENSG00000157168 E002 0.0000000       8 31639245 31639303 59 +      
ENSG00000157168 E003 0.0000000       8 31639304 31639308 5 +      
ENSG00000157168 E004 0.0000000       8 31639309 31639431 123 +      
ENSG00000157168 E005 0.0000000       8 31639755 31639984 230 +      
ENSG00000157168 E006 0.0000000       8 31639985 31640425 441 +      
ENSG00000157168 E007 0.0000000       8 31640426 31640658 233 +      
ENSG00000157168 E008 0.0000000       8 31640659 31640729 71 +      
ENSG00000157168 E009 0.0000000       8 31641753 31641769 17 +      
ENSG00000157168 E010 0.0000000       8 32171382 32171458 77 +      
ENSG00000157168 E011 0.0000000       8 32220928 32221041 114 +      
ENSG00000157168 E012 0.0000000       8 32221042 32221133 92 +      
ENSG00000157168 E013 0.0000000       8 32287101 32287566 466 +      
ENSG00000157168 E014 0.0000000       8 32548210 32548234 25 +      
ENSG00000157168 E015 0.0000000       8 32548235 32548266 32 +      
ENSG00000157168 E016 0.0000000       8 32548267 32548289 23 +      
ENSG00000157168 E017 0.3527111 0.0268600335 1.000000e+00   8 32548290 32548310 21 + 0.108 0.000 -7.970
ENSG00000157168 E018 2.7234756 0.0049515971 1.658331e-01 4.357423e-01 8 32548311 32548326 16 + 0.488 0.213 -1.710
ENSG00000157168 E019 19.7061433 0.0029191122 1.176861e-01 3.623911e-01 8 32548327 32548589 263 + 1.183 1.022 -0.582
ENSG00000157168 E020 6.4208131 0.0023575850 6.770810e-01 8.661023e-01 8 32548590 32548618 29 + 0.743 0.682 -0.250
ENSG00000157168 E021 5.5859941 0.0035340332 3.373282e-01 6.290913e-01 8 32548619 32548634 16 + 0.704 0.549 -0.677
ENSG00000157168 E022 7.1311666 0.0103294701 2.700595e-01 5.636978e-01 8 32548635 32548661 27 + 0.792 0.621 -0.710
ENSG00000157168 E023 10.7042260 0.0276947267 2.947682e-01 5.880110e-01 8 32548662 32548729 68 + 0.942 0.784 -0.609
ENSG00000157168 E024 16.1840216 0.0235419664 4.268546e-01 7.054382e-01 8 32548730 32548826 97 + 1.098 0.995 -0.374
ENSG00000157168 E025 0.1170040 0.0117087514 5.913842e-01   8 32554944 32555057 114 + 0.039 0.000 -8.443
ENSG00000157168 E026 27.6439803 0.0015766877 8.271224e-01 9.374329e-01 8 32595828 32596005 178 + 1.304 1.288 -0.058
ENSG00000157168 E027 20.5844312 0.0007232163 4.209454e-01 7.001132e-01 8 32605562 32605647 86 + 1.191 1.116 -0.269
ENSG00000157168 E028 11.6447649 0.0011301596 2.406896e-01 5.298943e-01 8 32605648 32605683 36 + 0.973 0.827 -0.556
ENSG00000157168 E029 0.2363338 0.0156824454 1.000000e+00   8 32614375 32614513 139 + 0.075 0.000 -9.364
ENSG00000157168 E030 13.4551916 0.0010638772 8.492751e-01 9.464293e-01 8 32614514 32614564 51 + 1.015 0.995 -0.072
ENSG00000157168 E031 16.6416741 0.0008366977 2.749925e-01 5.684942e-01 8 32616835 32616885 51 + 1.110 0.995 -0.420
ENSG00000157168 E032 0.0000000       8 32646958 32646966 9 +      
ENSG00000157168 E033 0.0000000       8 32646967 32647102 136 +      
ENSG00000157168 E034 0.0000000       8 32647103 32647116 14 +      
ENSG00000157168 E035 0.0000000       8 32647117 32647201 85 +      
ENSG00000157168 E036 1.8590542 0.0103730709 2.052827e-06 8.697343e-05 8 32647202 32647961 760 + 0.168 0.866 3.750
ENSG00000157168 E037 0.8496129 0.1105973021 6.429944e-02 2.553629e-01 8 32647962 32648144 183 + 0.139 0.463 2.336
ENSG00000157168 E038 0.3608620 0.1459305595 2.962037e-01   8 32648145 32648194 50 + 0.075 0.213 1.751
ENSG00000157168 E039 0.3707734 0.0165514009 2.697667e-02   8 32648195 32648314 120 + 0.039 0.356 3.750
ENSG00000157168 E040 0.3720293 0.0168323424 2.694484e-02   8 32648315 32648384 70 + 0.039 0.356 3.750
ENSG00000157168 E041 0.0000000       8 32721753 32721818 66 +      
ENSG00000157168 E042 0.0000000       8 32721819 32721832 14 +      
ENSG00000157168 E043 0.0000000       8 32721833 32721844 12 +      
ENSG00000157168 E044 0.0000000       8 32721845 32722042 198 +      
ENSG00000157168 E045 29.8988615 0.0004899106 9.105510e-01 9.716700e-01 8 32727949 32728078 130 + 1.336 1.329 -0.025
ENSG00000157168 E046 0.5912407 0.0153788327 9.064361e-01 9.701677e-01 8 32728079 32728623 545 + 0.168 0.000 -10.584
ENSG00000157168 E047 18.8337942 0.0012935393 9.088091e-01 9.711026e-01 8 32742008 32742075 68 + 1.144 1.156 0.044
ENSG00000157168 E048 4.4110813 0.0030631095 9.247157e-01 9.771507e-01 8 32742675 32742733 59 + 0.604 0.621 0.072
ENSG00000157168 E049 6.6619765 0.0031481741 6.059628e-01 8.284111e-01 8 32742734 32743253 520 + 0.757 0.682 -0.309
ENSG00000157168 E050 0.8514970 0.0144378782 5.261994e-02 2.279521e-01 8 32748824 32749560 737 + 0.139 0.463 2.335
ENSG00000157168 E051 0.3621491 0.0165477459 2.878012e-01   8 32749561 32749584 24 + 0.075 0.213 1.750
ENSG00000157168 E052 1.3142819 0.0095767039 6.264674e-01 8.394820e-01 8 32749585 32749903 319 + 0.267 0.356 0.580
ENSG00000157168 E053 0.1187032 0.0118301044 5.914081e-01   8 32751063 32751155 93 + 0.039 0.000 -8.442
ENSG00000157168 E054 27.0761639 0.0005040399 4.437871e-02 2.059312e-01 8 32754372 32754474 103 + 1.315 1.137 -0.629
ENSG00000157168 E055 32.8277777 0.0054927856 3.020062e-01 5.952058e-01 8 32756403 32756529 127 + 1.362 1.442 0.278
ENSG00000157168 E056 35.1800645 0.0004486568 6.399650e-01 8.469926e-01 8 32759306 32759436 131 + 1.397 1.432 0.119
ENSG00000157168 E057 41.1287428 0.0003792212 7.216328e-01 8.879595e-01 8 32760200 32760406 207 + 1.464 1.489 0.085
ENSG00000157168 E058 14.0390851 0.0163743007 1.288403e-02 9.473582e-02 8 32760407 32762021 1615 + 0.982 1.243 0.942
ENSG00000157168 E059 7.2910973 0.0028119828 2.663800e-01 5.598528e-01 8 32763218 32763359 142 + 0.757 0.902 0.565
ENSG00000157168 E060 559.7613930 0.0001190937 7.380216e-01 8.960661e-01 8 32763748 32774046 10299 + 2.587 2.593 0.019
ENSG00000157168 E061 0.0000000       8 32854328 32855666 1339 +      

Help

Please Click HERE to learn more details about the results from DEXseq.