ENSG00000157184

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371486 ENSG00000157184 No_inf pgKDN_inf CPT2 protein_coding protein_coding 22.57248 23.43198 23.55121 1.842987 0.6245027 0.007318986 11.848417 6.129326 16.153409 3.543610 1.0837439 1.3965794 0.54334167 0.29795 0.689250 0.391300 0.54748399 0.01329755 FALSE TRUE
ENST00000636867 ENSG00000157184 No_inf pgKDN_inf CPT2 protein_coding protein_coding 22.57248 23.43198 23.55121 1.842987 0.6245027 0.007318986 3.135931 1.704991 3.628074 1.100427 1.4083418 1.0849738 0.13825833 0.06840 0.153575 0.085175 0.76935360 0.01329755 FALSE TRUE
ENST00000636935 ENSG00000157184 No_inf pgKDN_inf CPT2 protein_coding protein_coding 22.57248 23.43198 23.55121 1.842987 0.6245027 0.007318986 1.938206 5.814617 0.000000 2.329625 0.0000000 -9.1860194 0.07616667 0.22850 0.000000 -0.228500 0.01329755 0.01329755 FALSE TRUE
ENST00000637252 ENSG00000157184 No_inf pgKDN_inf CPT2 protein_coding protein_coding 22.57248 23.43198 23.55121 1.842987 0.6245027 0.007318986 1.083725 1.427189 1.151600 1.104019 0.4198337 -0.3071362 0.05234167 0.07540 0.048975 -0.026425 0.86529204 0.01329755 FALSE TRUE
ENST00000638135 ENSG00000157184 No_inf pgKDN_inf CPT2 protein_coding nonsense_mediated_decay 22.57248 23.43198 23.55121 1.842987 0.6245027 0.007318986 3.453290 7.612360 1.150567 3.476999 1.1505673 -2.7154076 0.14030833 0.29755 0.047075 -0.250475 0.24916339 0.01329755 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157184 E001 0.0000000       1 53196792 53196799 8 +      
ENSG00000157184 E002 0.2537694 0.0160724224 0.220717530   1 53196800 53196812 13 + 0.000 0.178 10.300
ENSG00000157184 E003 0.4995438 0.0157444043 0.288888168   1 53196813 53196819 7 + 0.092 0.245 1.684
ENSG00000157184 E004 1.2258547 0.0109406646 0.918590241 0.97439961 1 53196820 53196823 4 + 0.339 0.355 0.099
ENSG00000157184 E005 2.7020543 0.0069157805 0.565042638 0.80405356 1 53196824 53196858 35 + 0.527 0.606 0.362
ENSG00000157184 E006 5.4049333 0.0026877451 0.409153007 0.69133224 1 53196859 53196902 44 + 0.758 0.850 0.362
ENSG00000157184 E007 16.4100278 0.0010380556 0.691065213 0.87323515 1 53196903 53197095 193 + 1.227 1.255 0.099
ENSG00000157184 E008 0.0000000       1 53197303 53197507 205 +      
ENSG00000157184 E009 0.1187032 0.0118532154 0.573991332   1 53199777 53200718 942 + 0.092 0.000 -11.789
ENSG00000157184 E010 10.5802829 0.0014059802 0.182941791 0.45963825 1 53200719 53200799 81 + 1.116 1.005 -0.404
ENSG00000157184 E011 0.4896974 0.0162311622 0.946756529   1 53200800 53202322 1523 + 0.168 0.178 0.099
ENSG00000157184 E012 7.6175638 0.0198716163 0.055478811 0.23465539 1 53202323 53202429 107 + 1.029 0.818 -0.799
ENSG00000157184 E013 1.5979214 0.0098264023 0.695586983 0.87576057 1 53202430 53204315 1886 + 0.384 0.443 0.321
ENSG00000157184 E014 2.6216202 0.0074421242 0.009888112 0.07966917 1 53207475 53210014 2540 + 0.339 0.704 1.777
ENSG00000157184 E015 73.4911821 0.0004275708 0.081684217 0.29393892 1 53210015 53211250 1236 + 1.894 1.849 -0.151
ENSG00000157184 E016 5.7509664 0.0026488040 0.937911432 0.98211507 1 53211251 53211319 69 + 0.825 0.834 0.038
ENSG00000157184 E017 0.8687779 0.1525899023 0.267158588 0.56041894 1 53211320 53211369 50 + 0.168 0.355 1.422
ENSG00000157184 E018 2.1259485 0.1193378110 0.053661328 0.23064470 1 53211370 53211545 176 + 0.289 0.633 1.799
ENSG00000157184 E019 1.9487709 0.0083924865 0.712419560 0.88383026 1 53212781 53212816 36 + 0.495 0.443 -0.264
ENSG00000157184 E020 30.1914832 0.0012567111 0.171020528 0.44340410 1 53213264 53214197 934 + 1.457 1.527 0.240

Help

Please Click HERE to learn more details about the results from DEXseq.