ENSG00000157193

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000529670 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding nonsense_mediated_decay 39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 10.8325097 3.973537 13.2552782 0.5894969 2.7416018 1.7355331 0.25808333 0.21260 0.282025 0.069425 0.81598425 0.04447434 TRUE TRUE
ENST00000653217 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding protein_coding 39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 5.3453752 2.705218 4.8073654 0.3928187 1.8039287 0.8271765 0.13683333 0.14600 0.108325 -0.037675 0.83467830 0.04447434 FALSE TRUE
ENST00000657047 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding nonsense_mediated_decay 39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 0.8775653 1.260439 0.7510075 0.2967748 0.4004455 -0.7393441 0.03236667 0.06885 0.016675 -0.052175 0.32126531 0.04447434 TRUE TRUE
ENST00000662198 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding protein_coding 39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 2.0861385 0.000000 5.1556596 0.0000000 3.5373126 9.0128088 0.04185833 0.00000 0.105125 0.105125 0.63721412 0.04447434 FALSE TRUE
ENST00000668071 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding protein_coding 39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 6.3756736 0.000000 7.4492944 0.0000000 2.7397196 9.5428953 0.12689167 0.00000 0.166850 0.166850 0.04447434 0.04447434 FALSE TRUE
MSTRG.1053.2 ENSG00000157193 No_inf pgKDN_inf LRP8 protein_coding   39.7826 18.47578 46.18448 0.6303973 1.609258 1.321305 7.5675114 6.315494 8.0970852 0.4711399 0.1483188 0.3580051 0.22390833 0.34480 0.175825 -0.168975 0.10900019 0.04447434 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157193 E001 0.0000000       1 53242364 53242385 22 -      
ENSG00000157193 E002 0.0000000       1 53242386 53242404 19 -      
ENSG00000157193 E003 0.0000000       1 53242405 53242405 1 -      
ENSG00000157193 E004 107.9034053 0.0005070443 5.074582e-17 1.044628e-14 1 53242406 53245541 3136 - 1.918 2.156 0.800
ENSG00000157193 E005 1.8106805 0.0191120687 8.883765e-01 9.627227e-01 1 53245542 53245544 3 - 0.447 0.426 -0.108
ENSG00000157193 E006 1.8106805 0.0191120687 8.883765e-01 9.627227e-01 1 53245545 53245545 1 - 0.447 0.426 -0.108
ENSG00000157193 E007 1.8106805 0.0191120687 8.883765e-01 9.627227e-01 1 53245546 53245546 1 - 0.447 0.426 -0.108
ENSG00000157193 E008 4.8009542 0.0031725229 8.586378e-02 3.034156e-01 1 53245547 53245551 5 - 0.818 0.602 -0.892
ENSG00000157193 E009 7.6287651 0.0125959199 9.715679e-01 9.945334e-01 1 53245552 53245579 28 - 0.923 0.921 -0.006
ENSG00000157193 E010 7.2614176 0.0038175081 7.734229e-01 9.128700e-01 1 53245580 53245590 11 - 0.913 0.885 -0.108
ENSG00000157193 E011 9.7576296 0.0014496533 1.273710e-01 3.784918e-01 1 53245591 53245623 33 - 1.065 0.921 -0.531
ENSG00000157193 E012 17.0618525 0.0109730034 1.138440e-02 8.761504e-02 1 53245624 53245681 58 - 1.310 1.091 -0.776
ENSG00000157193 E013 23.1599878 0.0006028433 7.795541e-02 2.856088e-01 1 53245682 53245981 300 - 1.405 1.294 -0.388
ENSG00000157193 E014 6.7215396 0.0020209187 6.681772e-02 2.604428e-01 1 53245982 53246551 570 - 0.793 0.985 0.734
ENSG00000157193 E015 6.4209990 0.0021907332 9.138972e-01 9.728871e-01 1 53246552 53246552 1 - 0.852 0.865 0.052
ENSG00000157193 E016 9.8786006 0.0013670035 8.612604e-02 3.040001e-01 1 53246553 53246557 5 - 0.958 1.114 0.570
ENSG00000157193 E017 11.3497941 0.0012023583 4.768828e-02 2.147466e-01 1 53246558 53246567 10 - 1.007 1.176 0.612
ENSG00000157193 E018 12.5422255 0.0011631902 1.137473e-01 3.550752e-01 1 53246568 53246578 11 - 1.065 1.195 0.469
ENSG00000157193 E019 12.5683437 0.0017631815 3.049427e-02 1.643256e-01 1 53246579 53246594 16 - 1.044 1.222 0.639
ENSG00000157193 E020 24.6895180 0.0141877003 8.172402e-01 9.335783e-01 1 53246595 53246709 115 - 1.399 1.386 -0.045
ENSG00000157193 E021 36.1360036 0.0004665750 2.647135e-01 5.577978e-01 1 53246710 53246917 208 - 1.574 1.519 -0.188
ENSG00000157193 E022 10.7277283 0.0014579609 1.592633e-01 4.266056e-01 1 53246918 53246923 6 - 1.097 0.970 -0.464
ENSG00000157193 E023 13.6305205 0.0015554312 1.844109e-01 4.615722e-01 1 53246924 53246955 32 - 1.187 1.079 -0.386
ENSG00000157193 E024 19.9635891 0.0018949264 5.238235e-01 7.769531e-01 1 53246956 53247017 62 - 1.321 1.279 -0.148
ENSG00000157193 E025 18.9766851 0.0007872048 3.855581e-01 6.715049e-01 1 53247018 53247056 39 - 1.306 1.247 -0.206
ENSG00000157193 E026 2.0786094 0.0188454669 3.288316e-01 6.212933e-01 1 53248463 53248591 129 - 0.418 0.564 0.722
ENSG00000157193 E027 7.4160605 0.0020890093 4.988010e-01 7.591809e-01 1 53249380 53249440 61 - 0.884 0.954 0.267
ENSG00000157193 E028 5.2049421 0.0504929896 8.079108e-01 9.291044e-01 1 53249441 53249495 55 - 0.793 0.753 -0.159
ENSG00000157193 E029 6.0481964 0.0952556469 8.702420e-01 9.552531e-01 1 53249496 53249556 61 - 0.852 0.802 -0.196
ENSG00000157193 E030 24.7146657 0.0056012780 8.306379e-01 9.386350e-01 1 53250690 53250764 75 - 1.399 1.386 -0.045
ENSG00000157193 E031 23.4258756 0.0017458702 5.383341e-01 7.871254e-01 1 53250765 53250862 98 - 1.357 1.398 0.143
ENSG00000157193 E032 8.9473050 0.0018356367 6.277624e-01 8.400087e-01 1 53251676 53252537 862 - 0.999 0.954 -0.167
ENSG00000157193 E033 0.1268540 0.0123446417 2.798901e-01   1 53254911 53254957 47 - 0.000 0.125 12.028
ENSG00000157193 E034 11.3207222 0.0021914071 1.819786e-01 4.579766e-01 1 53255117 53255124 8 - 1.029 1.146 0.422
ENSG00000157193 E035 20.4566586 0.0155864389 8.468072e-01 9.456456e-01 1 53255125 53255185 61 - 1.321 1.308 -0.044
ENSG00000157193 E036 1.2684073 0.0103982772 1.274826e-05 4.202718e-04 1 53255186 53257239 2054 - 0.000 0.637 15.258
ENSG00000157193 E037 32.0461003 0.0006294736 1.553905e-02 1.077265e-01 1 53257240 53257464 225 - 1.548 1.415 -0.457
ENSG00000157193 E038 0.8360076 0.0247793181 2.280096e-01 5.164617e-01 1 53258009 53258074 66 - 0.318 0.125 -1.693
ENSG00000157193 E039 21.6360381 0.0006931044 3.524378e-01 6.424535e-01 1 53258319 53258465 147 - 1.360 1.301 -0.206
ENSG00000157193 E040 7.0118341 0.0024447768 5.133987e-01 7.702266e-01 1 53258466 53258471 6 - 0.913 0.845 -0.260
ENSG00000157193 E041 19.7659359 0.0008496400 5.347557e-02 2.302452e-01 1 53260464 53260605 142 - 1.346 1.213 -0.467
ENSG00000157193 E042 0.4978456 0.0330593196 1.119869e-01   1 53261213 53261787 575 - 0.072 0.301 2.477
ENSG00000157193 E043 26.7247175 0.0005325520 4.217016e-01 7.008521e-01 1 53262068 53262207 140 - 1.444 1.398 -0.157
ENSG00000157193 E044 21.4982374 0.0007302214 3.006874e-01 5.936045e-01 1 53262446 53262564 119 - 1.360 1.294 -0.231
ENSG00000157193 E045 10.5244453 0.0319652595 9.444401e-01 9.845722e-01 1 53264169 53264215 47 - 1.051 1.042 -0.033
ENSG00000157193 E046 24.2686858 0.0188164861 4.789056e-01 7.448108e-01 1 53264216 53264396 181 - 1.408 1.349 -0.205
ENSG00000157193 E047 22.5026934 0.0010934276 1.469953e-02 1.036617e-01 1 53266473 53266647 175 - 1.409 1.247 -0.562
ENSG00000157193 E048 0.2533610 0.0160173713 9.364877e-02   1 53266648 53266699 52 - 0.000 0.222 13.001
ENSG00000157193 E049 1.1055170 0.0109747508 2.168974e-01 5.031459e-01 1 53266700 53268598 1899 - 0.235 0.426 1.214
ENSG00000157193 E050 18.5702803 0.0099022987 2.250955e-01 5.127249e-01 1 53271028 53271153 126 - 1.310 1.213 -0.339
ENSG00000157193 E051 14.0714757 0.0013698336 4.713289e-02 2.132865e-01 1 53271227 53271346 120 - 1.216 1.054 -0.580
ENSG00000157193 E052 0.5077596 0.0150393246 9.087599e-03 7.552562e-02 1 53271347 53271415 69 - 0.000 0.368 13.978
ENSG00000157193 E053 3.5741947 0.0039697923 1.095607e-02 8.537762e-02 1 53271416 53272603 1188 - 0.499 0.824 1.394
ENSG00000157193 E054 0.3722815 0.0164741951 2.739511e-01   1 53272604 53272642 39 - 0.072 0.222 1.892
ENSG00000157193 E055 6.3692707 0.0022001981 2.972998e-02 1.621127e-01 1 53272643 53275630 2988 - 0.754 0.985 0.892
ENSG00000157193 E056 7.1060314 0.0031980889 1.955561e-01 4.758850e-01 1 53275631 53275654 24 - 0.941 0.802 -0.534
ENSG00000157193 E057 10.9352242 0.0758086731 1.270315e-01 3.777954e-01 1 53275655 53275753 99 - 1.127 0.921 -0.757
ENSG00000157193 E058 8.7725438 0.0016732089 1.685696e-01 4.398822e-01 1 53276692 53277078 387 - 0.923 1.054 0.489
ENSG00000157193 E059 6.9319530 0.0020899316 2.688232e-03 3.177451e-02 1 53280587 53280715 129 - 0.983 0.637 -1.371
ENSG00000157193 E060 0.0000000       1 53289332 53289566 235 -      
ENSG00000157193 E061 0.0000000       1 53289567 53289689 123 -      
ENSG00000157193 E062 0.0000000       1 53291789 53291790 2 -      
ENSG00000157193 E063 0.0000000       1 53291791 53291917 127 -      
ENSG00000157193 E064 0.1265070 0.0122659441 2.799885e-01   1 53291918 53292028 111 - 0.000 0.125 12.029
ENSG00000157193 E065 0.4994178 0.0241984116 1.107333e-01   1 53292029 53292292 264 - 0.072 0.301 2.477
ENSG00000157193 E066 0.0000000       1 53295799 53296104 306 -      
ENSG00000157193 E067 0.0000000       1 53312969 53313143 175 -      
ENSG00000157193 E068 0.2363338 0.0156670171 5.376684e-01   1 53313573 53313743 171 - 0.133 0.000 -11.729
ENSG00000157193 E069 7.2010205 0.0020462199 2.424278e-02 1.426790e-01 1 53326873 53326992 120 - 0.975 0.727 -0.962
ENSG00000157193 E070 0.3809057 0.0158191193 2.899714e-02   1 53327258 53327463 206 - 0.000 0.301 13.573
ENSG00000157193 E071 9.0279639 0.0021825803 1.207614e-01 3.675797e-01 1 53327789 53328469 681 - 1.037 0.885 -0.568

Help

Please Click HERE to learn more details about the results from DEXseq.