ENSG00000157483

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000558571 ENSG00000157483 No_inf pgKDN_inf MYO1E protein_coding nonsense_mediated_decay 207.3703 152.2818 268.0533 4.466777 3.388807 0.8157353 34.68834 16.877175 47.46770 2.5477698 1.515678 1.4913220 0.16172500 0.109775 0.176975 0.067200 0.187963456 0.005419205 TRUE  
ENST00000558646 ENSG00000157483 No_inf pgKDN_inf MYO1E protein_coding retained_intron 207.3703 152.2818 268.0533 4.466777 3.388807 0.8157353 14.57237 13.267957 18.93661 1.1139464 2.955822 0.5129068 0.07100833 0.087700 0.071025 -0.016675 0.829478471 0.005419205    
ENST00000559412 ENSG00000157483 No_inf pgKDN_inf MYO1E protein_coding protein_coding 207.3703 152.2818 268.0533 4.466777 3.388807 0.8157353 45.56650 42.850494 55.86304 2.4184260 6.391364 0.3825039 0.22566667 0.281050 0.207725 -0.073325 0.328687902 0.005419205 FALSE  
ENST00000560749 ENSG00000157483 No_inf pgKDN_inf MYO1E protein_coding protein_coding 207.3703 152.2818 268.0533 4.466777 3.388807 0.8157353 10.37945 1.025569 19.71320 1.0255690 3.473073 4.2513979 0.04323333 0.006275 0.073925 0.067650 0.005419205 0.005419205 FALSE  
MSTRG.9665.2 ENSG00000157483 No_inf pgKDN_inf MYO1E protein_coding   207.3703 152.2818 268.0533 4.466777 3.388807 0.8157353 87.29843 65.838095 108.74117 0.5155518 1.215855 0.7238173 0.42527500 0.433475 0.405725 -0.027750 0.821506067 0.005419205 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157483 E001 57.9159600 2.551338e-04 1.728824e-14 2.834115e-12 15 59132434 59136365 3932 - 1.609 1.914 1.032
ENSG00000157483 E002 275.6897593 7.848279e-05 1.949931e-03 2.508170e-02 15 59136366 59136777 412 - 2.412 2.468 0.186
ENSG00000157483 E003 400.1879968 3.783635e-04 6.809461e-04 1.110558e-02 15 59136778 59137456 679 - 2.574 2.629 0.183
ENSG00000157483 E004 81.5798142 2.238404e-04 6.305170e-02 2.526284e-01 15 59138198 59138291 94 - 1.884 1.947 0.212
ENSG00000157483 E005 74.2792770 2.051824e-04 5.154448e-01 7.714885e-01 15 59138292 59138367 76 - 1.862 1.885 0.078
ENSG00000157483 E006 138.3459191 1.188840e-03 1.252975e-01 3.752454e-01 15 59153590 59153791 202 - 2.120 2.164 0.150
ENSG00000157483 E007 85.2837749 1.287729e-03 2.830229e-01 5.767025e-01 15 59158287 59158379 93 - 1.914 1.953 0.130
ENSG00000157483 E008 110.1488434 8.922398e-04 5.328874e-01 7.834041e-01 15 59161073 59161230 158 - 2.049 2.030 -0.065
ENSG00000157483 E009 82.9578780 1.869948e-04 3.146593e-01 6.076202e-01 15 59163157 59163218 62 - 1.905 1.938 0.114
ENSG00000157483 E010 105.4601180 2.595488e-04 6.694159e-02 2.607937e-01 15 59163219 59163303 85 - 1.998 2.053 0.184
ENSG00000157483 E011 138.9236744 4.671598e-04 3.809342e-01 6.673804e-01 15 59171897 59172042 146 - 2.131 2.155 0.080
ENSG00000157483 E012 166.6234069 1.841445e-04 7.642071e-02 2.826743e-01 15 59173746 59173915 170 - 2.237 2.195 -0.140
ENSG00000157483 E013 124.6651762 1.427808e-04 2.468051e-04 4.974284e-03 15 59174126 59174240 115 - 2.135 2.033 -0.339
ENSG00000157483 E014 54.1801499 2.646064e-04 2.997840e-02 1.629237e-01 15 59178393 59178423 31 - 1.773 1.683 -0.307
ENSG00000157483 E015 83.0531150 6.621239e-04 1.945204e-01 4.744387e-01 15 59178424 59178537 114 - 1.938 1.893 -0.151
ENSG00000157483 E016 85.3565534 1.156847e-03 7.951573e-01 9.221637e-01 15 59188118 59188216 99 - 1.935 1.926 -0.030
ENSG00000157483 E017 56.1826873 2.753479e-04 3.116614e-01 6.048850e-01 15 59195461 59195496 36 - 1.734 1.776 0.140
ENSG00000157483 E018 78.9227722 1.851371e-04 7.502471e-01 9.014829e-01 15 59195497 59195567 71 - 1.902 1.892 -0.036
ENSG00000157483 E019 84.6808335 2.819336e-03 9.230221e-02 3.155570e-01 15 59202326 59202407 82 - 1.955 1.888 -0.225
ENSG00000157483 E020 68.9036827 7.136453e-03 1.858814e-01 4.638565e-01 15 59205400 59205485 86 - 1.867 1.801 -0.222
ENSG00000157483 E021 0.1271363 1.237103e-02 3.673778e-01   15 59206706 59206761 56 - 0.000 0.112 12.164
ENSG00000157483 E022 64.7356790 1.002215e-03 4.187792e-02 1.991167e-01 15 59208681 59208808 128 - 1.846 1.765 -0.273
ENSG00000157483 E023 37.1955307 3.942359e-04 7.336925e-01 8.941774e-01 15 59208809 59208848 40 - 1.584 1.568 -0.056
ENSG00000157483 E024 1.8613523 7.488517e-03 4.654723e-02 2.117359e-01 15 59208849 59209000 152 - 0.305 0.596 1.536
ENSG00000157483 E025 57.7436944 2.732095e-04 6.461085e-01 8.502432e-01 15 59210514 59210600 87 - 1.772 1.754 -0.061
ENSG00000157483 E026 57.0757583 2.527432e-04 9.619587e-01 9.916848e-01 15 59214228 59214314 87 - 1.758 1.760 0.008
ENSG00000157483 E027 61.5233911 2.683752e-04 8.847798e-01 9.611682e-01 15 59214640 59214720 81 - 1.794 1.788 -0.018
ENSG00000157483 E028 110.6158119 1.834916e-04 6.100386e-01 8.304137e-01 15 59217891 59218087 197 - 2.049 2.035 -0.049
ENSG00000157483 E029 1.4768899 8.901991e-03 2.287731e-01 5.174891e-01 15 59218227 59218296 70 - 0.305 0.486 1.022
ENSG00000157483 E030 68.2640087 2.185587e-04 3.691929e-01 6.574454e-01 15 59223059 59223191 133 - 1.849 1.817 -0.111
ENSG00000157483 E031 63.2788587 2.289238e-04 2.964325e-01 5.895639e-01 15 59224689 59224823 135 - 1.820 1.780 -0.134
ENSG00000157483 E032 35.4603347 9.805041e-04 4.693499e-01 7.374131e-01 15 59227459 59227482 24 - 1.573 1.535 -0.127
ENSG00000157483 E033 62.3583474 2.658787e-03 9.956015e-02 3.296708e-01 15 59227483 59227590 108 - 1.826 1.754 -0.246
ENSG00000157483 E034 43.9592818 7.368045e-04 1.450863e-02 1.027183e-01 15 59231702 59231791 90 - 1.693 1.578 -0.393
ENSG00000157483 E035 39.5551890 3.507202e-04 1.734395e-01 4.467155e-01 15 59236585 59236672 88 - 1.630 1.564 -0.224
ENSG00000157483 E036 0.6264628 1.414213e-02 7.735430e-02 2.845088e-01 15 59242599 59242709 111 - 0.080 0.338 2.536
ENSG00000157483 E037 40.2910670 3.584659e-04 1.980164e-01 4.793885e-01 15 59256284 59256378 95 - 1.636 1.575 -0.210
ENSG00000157483 E038 36.9373332 4.236777e-04 1.099183e-04 2.571945e-03 15 59261420 59261509 90 - 1.648 1.449 -0.682
ENSG00000157483 E039 0.5060281 7.299731e-01 2.192376e-01 5.058767e-01 15 59264903 59264997 95 - 0.000 0.338 12.055
ENSG00000157483 E040 0.4818259 1.532643e-02 5.292243e-01   15 59272246 59272305 60 - 0.207 0.112 -1.049
ENSG00000157483 E041 43.6963630 3.209372e-04 8.716813e-03 7.331375e-02 15 59272306 59272449 144 - 1.693 1.571 -0.416
ENSG00000157483 E042 46.1905964 2.999826e-04 5.274338e-02 2.282302e-01 15 59372498 59372871 374 - 1.704 1.617 -0.296

Help

Please Click HERE to learn more details about the results from DEXseq.