ENSG00000157637

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288439 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding protein_coding 59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 9.314501 0.9906694 13.068806 0.9906694 0.9769562 3.7081936 0.15360000 0.016825 0.222025 0.205200 0.00248285 0.00248285 FALSE TRUE
ENST00000374759 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding protein_coding 59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 22.042803 25.4279596 20.647968 2.1596374 0.8298975 -0.3002846 0.37215000 0.446925 0.348475 -0.098450 0.56027880 0.00248285 FALSE TRUE
ENST00000539643 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding retained_intron 59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 4.216359 6.1020742 2.253449 3.5637701 1.3027199 -1.4331396 0.07124167 0.106925 0.039325 -0.067600 0.97248021 0.00248285 FALSE TRUE
ENST00000573058 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding retained_intron 59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 8.705271 5.4094344 11.047456 0.6461983 0.5900816 1.0288053 0.14520000 0.094225 0.186575 0.092350 0.15264105 0.00248285 FALSE TRUE
MSTRG.13440.4 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding   59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 6.558064 5.7268650 6.096080 1.4124634 0.5349900 0.0899839 0.10890833 0.098925 0.103000 0.004075 0.95522984 0.00248285 FALSE TRUE
MSTRG.13440.5 ENSG00000157637 No_inf pgKDN_inf SLC38A10 protein_coding   59.68195 57.26663 59.21646 1.294083 1.423566 0.04829538 3.578630 6.2365860 3.243606 3.7156251 1.8736475 -0.9410283 0.06117500 0.109275 0.053175 -0.056100 1.00000000 0.00248285 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157637 E001 0.4996088 0.0156897117 4.527292e-01   17 81244811 81244999 189 - 0.106 0.217 1.221
ENSG00000157637 E002 0.3714026 0.0167745663 7.485418e-01   17 81245000 81245001 2 - 0.106 0.156 0.636
ENSG00000157637 E003 1.2245025 0.0098912871 6.987540e-01 8.772607e-01 17 81245002 81245003 2 - 0.378 0.318 -0.364
ENSG00000157637 E004 280.9766531 0.0001020636 6.871011e-08 4.154497e-06 17 81245004 81246169 1166 - 2.392 2.479 0.288
ENSG00000157637 E005 18.7699821 0.0021612860 2.247139e-01 5.122668e-01 17 81246170 81246177 8 - 1.240 1.324 0.293
ENSG00000157637 E006 32.3219662 0.0008970390 5.304908e-03 5.174804e-02 17 81246178 81246240 63 - 1.424 1.574 0.513
ENSG00000157637 E007 17.7269398 0.0180316602 5.963208e-02 2.448756e-01 17 81246241 81246244 4 - 1.165 1.328 0.575
ENSG00000157637 E008 21.4401964 0.0122626014 3.184115e-02 1.686293e-01 17 81246245 81246271 27 - 1.240 1.408 0.586
ENSG00000157637 E009 72.5885593 0.0001968382 2.115231e-09 1.695139e-07 17 81246272 81246614 343 - 1.724 1.939 0.726
ENSG00000157637 E010 25.2700226 0.0006076913 1.903809e-06 8.149207e-05 17 81246615 81246673 59 - 1.219 1.515 1.028
ENSG00000157637 E011 9.0004454 0.0016121873 1.438063e-04 3.194419e-03 17 81246674 81246884 211 - 0.736 1.117 1.443
ENSG00000157637 E012 37.2384221 0.0003853062 1.500518e-05 4.843144e-04 17 81246885 81247058 174 - 1.437 1.655 0.746
ENSG00000157637 E013 4.3237708 0.0178163220 4.572816e-01 7.292511e-01 17 81247059 81247061 3 - 0.664 0.759 0.395
ENSG00000157637 E014 37.1674659 0.0003726989 8.023342e-12 9.187493e-10 17 81247062 81247925 864 - 1.333 1.693 1.234
ENSG00000157637 E015 1.5951212 0.2532547929 9.463446e-01 9.856643e-01 17 81250070 81250093 24 - 0.426 0.400 -0.139
ENSG00000157637 E016 14.9863118 0.0389979005 6.808449e-01 8.681671e-01 17 81250094 81250640 547 - 1.219 1.183 -0.126
ENSG00000157637 E017 19.2087990 0.0007506443 7.484695e-02 2.790926e-01 17 81250877 81251195 319 - 1.366 1.246 -0.419
ENSG00000157637 E018 0.0000000       17 81251196 81251492 297 -      
ENSG00000157637 E019 0.0000000       17 81251493 81251612 120 -      
ENSG00000157637 E020 8.8619298 0.0041161346 3.095048e-03 3.530303e-02 17 81251613 81252194 582 - 1.130 0.848 -1.048
ENSG00000157637 E021 111.0849762 0.0001558163 5.359252e-09 3.997869e-07 17 81252195 81252683 489 - 2.131 1.968 -0.545
ENSG00000157637 E022 57.4547989 0.0002485803 1.924353e-01 4.723220e-01 17 81253073 81253240 168 - 1.791 1.738 -0.179
ENSG00000157637 E023 37.2621223 0.0004572532 5.391736e-02 2.310175e-01 17 81260238 81260360 123 - 1.630 1.534 -0.326
ENSG00000157637 E024 16.9724089 0.0008395650 1.091368e-02 8.516738e-02 17 81260361 81260394 34 - 1.344 1.164 -0.635
ENSG00000157637 E025 31.2916136 0.0005199245 4.364929e-03 4.510789e-02 17 81270918 81271024 107 - 1.585 1.433 -0.522
ENSG00000157637 E026 34.3652696 0.0120625697 1.924352e-03 2.484156e-02 17 81272516 81272627 112 - 1.652 1.443 -0.713
ENSG00000157637 E027 45.3108007 0.0022207583 4.071210e-04 7.415624e-03 17 81275969 81276151 183 - 1.750 1.581 -0.574
ENSG00000157637 E028 30.9689011 0.0004350912 2.230433e-02 1.358436e-01 17 81277031 81277133 103 - 1.566 1.443 -0.421
ENSG00000157637 E029 0.6345490 0.0150310931 3.974423e-02 1.932184e-01 17 81279699 81280160 462 - 0.000 0.318 11.058
ENSG00000157637 E030 33.1028029 0.0004525522 1.218984e-01 3.693951e-01 17 81280609 81280733 125 - 1.573 1.491 -0.278
ENSG00000157637 E031 30.8310174 0.0004569648 1.353387e-02 9.787283e-02 17 81282189 81282332 144 - 1.569 1.437 -0.456
ENSG00000157637 E032 17.5559639 0.0007763763 2.972849e-03 3.432619e-02 17 81283409 81283502 94 - 1.371 1.164 -0.726
ENSG00000157637 E033 11.8935680 0.0229271114 5.735808e-03 5.463522e-02 17 81284850 81284895 46 - 1.247 0.964 -1.023
ENSG00000157637 E034 0.9992127 0.0206671385 2.788879e-01 5.721271e-01 17 81284896 81285714 819 - 0.192 0.361 1.221
ENSG00000157637 E035 0.2455571 0.0162214995 8.473150e-01   17 81288733 81288945 213 - 0.106 0.085 -0.364
ENSG00000157637 E036 20.4883090 0.0120713577 9.827724e-03 7.936045e-02 17 81289691 81289808 118 - 1.433 1.230 -0.709
ENSG00000157637 E037 45.5882468 0.0003400690 3.130180e-04 6.010079e-03 17 81294823 81295307 485 - 1.748 1.588 -0.542
ENSG00000157637 E038 0.0000000       17 81295422 81295547 126 -      

Help

Please Click HERE to learn more details about the results from DEXseq.