ENSG00000157654

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259318 ENSG00000157654 No_inf pgKDN_inf PALM2AKAP2 protein_coding protein_coding 5.38801 9.181908 2.8908 0.2901586 0.2296045 -1.663913 0.73883726 0.69719455 0.8146969 0.69719455 0.4719606 0.2217568 0.1957500 0.072925 0.323325 0.250400 0.64500265 0.02191576 FALSE TRUE
ENST00000302798 ENSG00000157654 No_inf pgKDN_inf PALM2AKAP2 protein_coding protein_coding 5.38801 9.181908 2.8908 0.2901586 0.2296045 -1.663913 0.09751456 0.04474263 0.2478011 0.04474263 0.1784399 2.2355217 0.0306250 0.005125 0.086750 0.081625 0.48205319 0.02191576 FALSE TRUE
ENST00000374525 ENSG00000157654 No_inf pgKDN_inf PALM2AKAP2 protein_coding protein_coding 5.38801 9.181908 2.8908 0.2901586 0.2296045 -1.663913 1.30034403 2.97244737 0.6156167 1.02373914 0.6156167 -2.2531458 0.2024917 0.326950 0.178050 -0.148900 0.62599768 0.02191576 FALSE TRUE
ENST00000482335 ENSG00000157654 No_inf pgKDN_inf PALM2AKAP2 protein_coding protein_coding_CDS_not_defined 5.38801 9.181908 2.8908 0.2901586 0.2296045 -1.663913 2.31433936 5.37981559 0.2620808 0.37314533 0.2620808 -4.3081290 0.3225000 0.585800 0.098125 -0.487675 0.02191576 0.02191576 FALSE FALSE
ENST00000495980 ENSG00000157654 No_inf pgKDN_inf PALM2AKAP2 protein_coding nonsense_mediated_decay 5.38801 9.181908 2.8908 0.2901586 0.2296045 -1.663913 0.48773097 0.00000000 0.6518436 0.00000000 0.4061712 6.0484185 0.1409750 0.000000 0.205375 0.205375 0.22311997 0.02191576 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157654 E001 0.0000000       9 109498325 109498700 376 +      
ENSG00000157654 E002 0.0000000       9 109514516 109514611 96 +      
ENSG00000157654 E003 0.0000000       9 109640788 109640866 79 +      
ENSG00000157654 E004 0.0000000       9 109780198 109780402 205 +      
ENSG00000157654 E005 0.0000000       9 109780403 109780438 36 +      
ENSG00000157654 E006 0.0000000       9 109780439 109780455 17 +      
ENSG00000157654 E007 0.0000000       9 109780456 109780487 32 +      
ENSG00000157654 E008 0.0000000       9 109780488 109780533 46 +      
ENSG00000157654 E009 0.0000000       9 109867031 109867074 44 +      
ENSG00000157654 E010 0.0000000       9 109867271 109867490 220 +      
ENSG00000157654 E011 0.1187032 0.0119330034 1.344223e-01   9 109867491 109867571 81 + 0.162 0.000 -12.908
ENSG00000157654 E012 0.1187032 0.0119330034 1.344223e-01   9 109880551 109880681 131 + 0.162 0.000 -14.338
ENSG00000157654 E013 0.1272623 0.0124208034 1.000000e+00   9 109923735 109923849 115 + 0.000 0.054 10.512
ENSG00000157654 E014 0.0000000       9 109925061 109925082 22 +      
ENSG00000157654 E015 0.2340080 0.2902203934 5.494417e-02   9 109931927 109932028 102 + 0.280 0.000 -14.707
ENSG00000157654 E016 0.4719109 0.0164827911 1.533981e-03   9 109942686 109943381 696 + 0.449 0.000 -16.138
ENSG00000157654 E017 1.7826787 0.2046107751 1.682516e-04 0.0036385253 9 109943382 109951476 8095 + 0.838 0.102 -4.475
ENSG00000157654 E018 0.3526461 0.0440234357 7.635133e-03   9 110015954 110016039 86 + 0.373 0.000 -15.662
ENSG00000157654 E019 0.0000000       9 110048598 110048695 98 +      
ENSG00000157654 E020 0.0000000       9 110048696 110048697 2 +      
ENSG00000157654 E021 0.7525912 0.0366053915 7.269990e-01 0.8908842541 9 110048698 110048855 158 + 0.162 0.220 0.545
ENSG00000157654 E022 0.0000000       9 110090197 110090416 220 +      
ENSG00000157654 E023 0.0000000       9 110125501 110125596 96 +      
ENSG00000157654 E024 0.7251186 0.0148552904 2.585113e-02 0.1485936903 9 110127646 110128012 367 + 0.449 0.102 -2.777
ENSG00000157654 E025 0.9623610 0.0118305885 2.261201e-03 0.0280293258 9 110136127 110136192 66 + 0.570 0.102 -3.362
ENSG00000157654 E026 30.2674710 0.0007993821 1.497206e-01 0.4120754941 9 110136193 110138170 1978 + 1.490 1.387 -0.354
ENSG00000157654 E027 9.0019095 0.0025834726 8.023354e-01 0.9263819858 9 110138171 110138539 369 + 0.916 0.924 0.030
ENSG00000157654 E028 0.0000000       9 110148528 110148703 176 +      
ENSG00000157654 E029 3.6083080 0.0044913929 6.089627e-01 0.8298288036 9 110156319 110156497 179 + 0.665 0.577 -0.385
ENSG00000157654 E030 0.1271363 0.0123501889 1.000000e+00   9 110162094 110162132 39 + 0.000 0.054 10.513
ENSG00000157654 E031 135.3544041 0.0001832385 7.839438e-06 0.0002767096 9 110168399 110172512 4114 + 2.005 2.060 0.185

Help

Please Click HERE to learn more details about the results from DEXseq.