ENSG00000157657

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288466 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding protein_coding 12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 2.0736989 1.895835 2.86239980 0.7280354 1.29420026 0.59183299 0.16321667 0.117000 0.224350 0.107350 0.85030232 0.03109726 FALSE TRUE
ENST00000374126 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding protein_coding 12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 1.0587707 0.000000 1.49494637 0.0000000 0.52121875 7.23356827 0.09687500 0.000000 0.119700 0.119700 0.03109726 0.03109726 FALSE TRUE
ENST00000470105 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding protein_coding_CDS_not_defined 12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 0.5086484 1.151817 0.07188396 0.3595996 0.04184052 -3.82665878 0.03624167 0.070750 0.006025 -0.064725 0.15223040 0.03109726 FALSE TRUE
ENST00000615615 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding protein_coding 12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 1.3386053 3.161566 0.30238209 0.5219324 0.30238209 -3.34381191 0.08809167 0.196200 0.025950 -0.170250 0.05501251 0.03109726 FALSE TRUE
MSTRG.29199.12 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding   12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 5.5955605 8.155817 5.58395900 1.1124189 1.06623953 -0.54572758 0.41746667 0.504875 0.459075 -0.045800 0.93115427 0.03109726 FALSE TRUE
MSTRG.29199.8 ENSG00000157657 No_inf pgKDN_inf ZNF618 protein_coding   12.91232 16.13552 12.36419 0.2666658 0.408045 -0.3837997 1.6737354 1.548843 1.56049696 1.0416264 1.56049696 0.01074538 0.14615833 0.097550 0.128800 0.031250 0.84294323 0.03109726 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157657 E001 0.0000000       9 113876282 113876308 27 +      
ENSG00000157657 E002 0.1170040 1.171934e-02 0.356271459   9 113876309 113876349 41 + 0.114 0.000 -11.460
ENSG00000157657 E003 0.3516386 3.194496e-02 0.047865480   9 113876350 113876381 32 + 0.278 0.000 -14.486
ENSG00000157657 E004 0.8341901 1.257316e-02 0.013715156 0.09867711 9 113876382 113876413 32 + 0.447 0.079 -3.167
ENSG00000157657 E005 0.4913925 7.849088e-02 0.705220721   9 113877952 113877977 26 + 0.204 0.146 -0.582
ENSG00000157657 E006 1.5531389 8.651752e-03 0.001071313 0.01578212 9 113969117 113969160 44 + 0.633 0.146 -3.041
ENSG00000157657 E007 1.2015003 1.238942e-02 0.011085094 0.08596168 9 113988321 113988324 4 + 0.531 0.146 -2.582
ENSG00000157657 E008 1.5548367 1.215340e-01 0.005229548 0.05126326 9 113988325 113988361 37 + 0.633 0.146 -3.042
ENSG00000157657 E009 7.0038026 6.019269e-03 0.419565850 0.69911223 9 113988362 113988580 219 + 0.944 0.857 -0.328
ENSG00000157657 E010 0.4712842 4.459869e-02 0.018244959   9 113998259 113998289 31 + 0.342 0.000 -14.829
ENSG00000157657 E011 0.6064155 2.026887e-02 0.377859300 0.66497417 9 113998290 113998321 32 + 0.278 0.146 -1.167
ENSG00000157657 E012 0.9715197 1.151868e-02 0.208136470 0.49185364 9 113998322 113998354 33 + 0.397 0.204 -1.319
ENSG00000157657 E013 6.8730128 3.986034e-02 0.395694066 0.68063670 9 114001996 114002073 78 + 0.944 0.845 -0.375
ENSG00000157657 E014 5.9301559 1.905917e-02 0.752274174 0.90241692 9 114002624 114002662 39 + 0.805 0.845 0.155
ENSG00000157657 E015 0.2435110 1.633167e-02 0.756739071   9 114004798 114004821 24 + 0.114 0.079 -0.582
ENSG00000157657 E016 7.1740749 1.860864e-03 0.540253958 0.78832468 9 114007350 114007439 90 + 0.863 0.924 0.235
ENSG00000157657 E017 4.3291867 1.753368e-02 0.726642206 0.89067796 9 114008344 114008379 36 + 0.690 0.733 0.177
ENSG00000157657 E018 6.3723883 1.050327e-02 0.173935054 0.44743229 9 114008477 114008554 78 + 0.944 0.793 -0.582
ENSG00000157657 E019 3.4299964 6.369230e-03 0.302143082 0.59533784 9 114016113 114016172 60 + 0.715 0.580 -0.582
ENSG00000157657 E020 6.3592283 5.262741e-03 0.095785320 0.32232709 9 114016695 114016784 90 + 0.958 0.778 -0.693
ENSG00000157657 E021 1.7671989 1.813452e-02 0.005998955 0.05647542 9 114027921 114028732 812 + 0.114 0.556 3.119
ENSG00000157657 E022 4.9639835 2.113271e-02 0.364503398 0.65318198 9 114028733 114028909 177 + 0.690 0.806 0.473
ENSG00000157657 E023 2.7436265 1.379793e-02 0.221406705 0.50855402 9 114028910 114028972 63 + 0.447 0.623 0.833
ENSG00000157657 E024 0.2541163 1.599541e-02 0.412244601   9 114030804 114030882 79 + 0.000 0.146 12.191
ENSG00000157657 E025 1.1169739 1.163407e-02 0.676993571 0.86610234 9 114032645 114032647 3 + 0.278 0.343 0.418
ENSG00000157657 E026 5.0533453 1.270348e-02 0.870315478 0.95528003 9 114032648 114032728 81 + 0.785 0.764 -0.084
ENSG00000157657 E027 0.8808000 1.805852e-02 0.143141591 0.40293995 9 114035191 114035235 45 + 0.114 0.343 2.003
ENSG00000157657 E028 5.2798612 6.850649e-03 0.410615525 0.69249962 9 114036300 114036377 78 + 0.844 0.748 -0.380
ENSG00000157657 E029 0.1272623 1.234326e-02 0.810381303   9 114037361 114037482 122 + 0.000 0.079 11.244
ENSG00000157657 E030 5.8594666 2.418474e-03 0.052602383 0.22794722 9 114047893 114047994 102 + 0.944 0.733 -0.823
ENSG00000157657 E031 614.0264813 8.979295e-05 0.001440207 0.01979892 9 114048651 114056593 7943 + 2.769 2.781 0.041

Help

Please Click HERE to learn more details about the results from DEXseq.