ENSG00000157869

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288723 ENSG00000157869 No_inf pgKDN_inf RAB28 protein_coding protein_coding 13.08162 11.19004 16.47678 0.8168422 2.940728 0.5578057 2.838522 2.787674 1.626200 1.381032 0.6050730 -0.7738788 0.24195000 0.231775 0.120775 -0.111000 0.8259075 0.0141327 FALSE TRUE
ENST00000330852 ENSG00000157869 No_inf pgKDN_inf RAB28 protein_coding protein_coding 13.08162 11.19004 16.47678 0.8168422 2.940728 0.5578057 6.982800 5.067892 10.999593 1.027382 0.6002303 1.1164596 0.53534167 0.475075 0.719825 0.244750 0.4737484 0.0141327 FALSE TRUE
ENST00000508274 ENSG00000157869 No_inf pgKDN_inf RAB28 protein_coding nonsense_mediated_decay 13.08162 11.19004 16.47678 0.8168422 2.940728 0.5578057 1.918647 3.334473 0.000000 1.226539 0.0000000 -8.3856352 0.16471667 0.293175 0.000000 -0.293175 0.0141327 0.0141327 TRUE FALSE
MSTRG.21548.8 ENSG00000157869 No_inf pgKDN_inf RAB28 protein_coding   13.08162 11.19004 16.47678 0.8168422 2.940728 0.5578057 1.050089 0.000000 3.150268 0.000000 3.1502675 8.3039029 0.04160833 0.000000 0.124825 0.124825 0.8566597 0.0141327 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157869 E001 0.1187032 0.0120094658 0.602487999   4 13361354 13361633 280 - 0.091 0.000 -9.043
ENSG00000157869 E002 0.6079886 0.0149717972 0.745373999 0.89925067 4 13367724 13367724 1 - 0.229 0.181 -0.430
ENSG00000157869 E003 51.4189712 0.0003135837 0.002298294 0.02831989 4 13367725 13368500 776 - 1.669 1.766 0.327
ENSG00000157869 E004 15.2503697 0.0220267699 0.848335433 0.94630403 4 13368501 13368650 150 - 1.225 1.196 -0.099
ENSG00000157869 E005 1.5676054 0.0105898525 0.234115351 0.52315120 4 13369871 13369882 12 - 0.490 0.308 -1.015
ENSG00000157869 E006 3.0559871 0.0048605153 0.939173345 0.98258951 4 13369883 13369965 83 - 0.604 0.613 0.039
ENSG00000157869 E007 0.6080536 0.0164610148 0.744846180 0.89897204 4 13371795 13371867 73 - 0.229 0.181 -0.430
ENSG00000157869 E008 7.8339088 0.0018875509 0.647711534 0.85124413 4 13376545 13376622 78 - 0.925 0.967 0.155
ENSG00000157869 E009 10.1822799 0.0014776646 0.389596321 0.67530277 4 13381491 13381594 104 - 1.012 1.083 0.259
ENSG00000157869 E010 0.3642603 0.2528988196 0.711476652   4 13425110 13425172 63 - 0.166 0.100 -0.846
ENSG00000157869 E011 0.0000000       4 13459863 13459920 58 -      
ENSG00000157869 E012 9.1376299 0.0016458757 0.416080891 0.69600128 4 13460699 13460828 130 - 1.040 0.967 -0.272
ENSG00000157869 E013 7.3650159 0.0021227362 0.009498141 0.07779021 4 13474318 13474406 89 - 1.031 0.771 -0.990
ENSG00000157869 E014 6.9283112 0.0021261661 0.290840977 0.58436901 4 13479430 13479526 97 - 0.949 0.841 -0.409
ENSG00000157869 E015 10.5716897 0.0014808157 0.115270984 0.35793557 4 13484076 13484365 290 - 1.124 0.990 -0.486

Help

Please Click HERE to learn more details about the results from DEXseq.