ENSG00000157873

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355716 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding protein_coding 40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 16.753879 5.4562537 16.699190 0.5953909 2.0175547 1.6120175 0.42145833 0.382700 0.497025 0.114325 0.749591454 0.007297103 FALSE  
ENST00000463471 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding retained_intron 40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 4.690617 2.0049795 3.233616 0.1697857 0.4026438 0.6868377 0.11874167 0.140150 0.095725 -0.044425 0.811259530 0.007297103 FALSE  
ENST00000480305 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding protein_coding_CDS_not_defined 40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 2.858475 0.8532518 1.076874 0.8532518 0.4967804 0.3323313 0.05774167 0.053950 0.031600 -0.022350 0.834678301 0.007297103 FALSE  
ENST00000496064 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding retained_intron 40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 5.703135 2.8143876 3.387221 0.1695044 0.9993353 0.2664171 0.14762500 0.195050 0.099875 -0.095175 0.486459865 0.007297103 FALSE  
MSTRG.107.1 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding   40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 1.487682 0.0000000 2.678644 0.0000000 0.6951306 8.0707350 0.03437500 0.000000 0.078425 0.078425 0.007297103 0.007297103 FALSE  
MSTRG.107.7 ENSG00000157873 No_inf pgKDN_inf TNFRSF14 protein_coding   40.6312 14.44692 33.64665 0.5535194 0.7298821 1.219131 2.876583 1.2613845 2.205538 0.4889268 1.6366321 0.8012564 0.07387500 0.086975 0.065575 -0.021400 0.829119614 0.007297103 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157873 E001 0.0000000       1 2555639 2555667 29 +      
ENSG00000157873 E002 0.0000000       1 2555791 2555801 11 +      
ENSG00000157873 E003 0.0000000       1 2555802 2555850 49 +      
ENSG00000157873 E004 0.0000000       1 2555851 2555977 127 +      
ENSG00000157873 E005 0.0000000       1 2555978 2555979 2 +      
ENSG00000157873 E006 0.0000000       1 2555980 2556032 53 +      
ENSG00000157873 E007 0.0000000       1 2556033 2556058 26 +      
ENSG00000157873 E008 0.0000000       1 2556059 2556198 140 +      
ENSG00000157873 E009 0.0000000       1 2556199 2556221 23 +      
ENSG00000157873 E010 0.0000000       1 2556222 2556252 31 +      
ENSG00000157873 E011 0.0000000       1 2556253 2556261 9 +      
ENSG00000157873 E012 0.0000000       1 2556371 2556385 15 +      
ENSG00000157873 E013 0.0000000       1 2556386 2556404 19 +      
ENSG00000157873 E014 0.0000000       1 2556405 2556405 1 +      
ENSG00000157873 E015 0.0000000       1 2556406 2556455 50 +      
ENSG00000157873 E016 0.0000000       1 2556456 2556556 101 +      
ENSG00000157873 E017 0.0000000       1 2556557 2556570 14 +      
ENSG00000157873 E018 0.0000000       1 2556571 2556584 14 +      
ENSG00000157873 E019 3.4782715 0.0405865780 0.146745758 0.40781634 1 2556585 2556733 149 + 0.699 0.486 -0.956
ENSG00000157873 E020 0.0000000       1 2557077 2557320 244 +      
ENSG00000157873 E021 12.2313562 0.0013376686 0.002764083 0.03246782 1 2557726 2557812 87 + 1.179 0.915 -0.964
ENSG00000157873 E022 8.2725512 0.0018977244 0.012332556 0.09199780 1 2557813 2557834 22 + 1.024 0.765 -0.991
ENSG00000157873 E023 20.6401553 0.0011524712 0.001028411 0.01531373 1 2558343 2558468 126 + 1.383 1.159 -0.787
ENSG00000157873 E024 9.0729907 0.0016738636 0.911649210 0.97179299 1 2558469 2558880 412 + 0.987 0.982 -0.017
ENSG00000157873 E025 7.9466947 0.0019770452 0.021935310 0.13445380 1 2558881 2559206 326 + 0.840 1.067 0.850
ENSG00000157873 E026 2.6559415 0.0428519955 0.861151388 0.95185395 1 2559207 2559351 145 + 0.558 0.533 -0.116
ENSG00000157873 E027 4.9721785 0.0046296339 0.723839939 0.88905681 1 2559352 2559579 228 + 0.742 0.790 0.190
ENSG00000157873 E028 5.3476916 0.0343080582 0.396214057 0.68096875 1 2559580 2559822 243 + 0.742 0.857 0.453
ENSG00000157873 E029 22.7040731 0.0093080299 0.008875184 0.07423607 1 2559823 2559978 156 + 1.413 1.226 -0.653
ENSG00000157873 E030 0.0000000       1 2560554 2560623 70 +      
ENSG00000157873 E031 13.8498633 0.0011131722 0.293004248 0.58664943 1 2560624 2560681 58 + 1.120 1.208 0.313
ENSG00000157873 E032 11.3167616 0.0031903159 0.167926391 0.43880533 1 2560682 2560714 33 + 1.024 1.149 0.450
ENSG00000157873 E033 14.0611247 0.0349981011 0.008024773 0.06927269 1 2560715 2561493 779 + 1.045 1.314 0.959
ENSG00000157873 E034 5.0480085 0.0136913770 0.002220164 0.02764135 1 2561494 2561672 179 + 0.598 0.967 1.481
ENSG00000157873 E035 11.5871828 0.0282386582 0.077322168 0.28444872 1 2561673 2561724 52 + 1.010 1.189 0.648
ENSG00000157873 E036 11.5105124 0.0741711242 0.645807968 0.85020033 1 2561725 2561776 52 + 1.065 1.104 0.140
ENSG00000157873 E037 10.6519666 0.0199953680 0.918385034 0.97439961 1 2561777 2561800 24 + 1.045 1.054 0.032
ENSG00000157873 E038 10.6484584 0.0013909970 0.973660343 0.99528822 1 2561801 2561815 15 + 1.045 1.054 0.032
ENSG00000157873 E039 3.4153595 0.1758381164 0.367771262 0.65638755 1 2561816 2561957 142 + 0.557 0.738 0.778
ENSG00000157873 E040 9.2597172 0.0017237020 0.138342716 0.39570302 1 2561958 2562864 907 + 0.938 1.080 0.524
ENSG00000157873 E041 15.2158778 0.0009461384 0.471255261 0.73869565 1 2562865 2562896 32 + 1.208 1.159 -0.174
ENSG00000157873 E042 10.0733980 0.0014531128 0.376757207 0.66394071 1 2562897 2563147 251 + 0.995 1.080 0.311
ENSG00000157873 E043 61.1607761 0.0015177808 0.388546915 0.67434499 1 2563148 2563829 682 + 1.783 1.757 -0.090
ENSG00000157873 E044 0.2357071 0.0157948767 0.573152474   1 2565053 2565382 330 + 0.130 0.000 -9.509

Help

Please Click HERE to learn more details about the results from DEXseq.