ENSG00000157954

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288828 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 2.479922 6.509519 0.0000000 2.2060791 0.0000000 -9.3486217 0.07878333 0.193300 0.000000 -0.193300 0.01247224 0.01247224 FALSE TRUE
ENST00000382384 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 2.765814 7.141257 1.1561850 2.5408165 1.1561850 -2.6164001 0.08316667 0.206275 0.043225 -0.163050 0.23923259 0.01247224 FALSE TRUE
ENST00000401525 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 8.228818 6.082903 9.9811010 2.5866651 0.6314763 0.7135139 0.28962500 0.192525 0.305525 0.113000 0.76405175 0.01247224 FALSE TRUE
ENST00000404704 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 5.564180 2.938820 5.9752896 2.9388196 2.0453485 1.0212835 0.19893333 0.090075 0.170925 0.080850 0.31397444 0.01247224 FALSE TRUE
ENST00000465102 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding retained_intron 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 1.675385 2.051547 2.6096577 1.3438348 2.6096577 0.3456511 0.05491667 0.063000 0.087150 0.024150 0.83046673 0.01247224 FALSE TRUE
ENST00000480238 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding_CDS_not_defined 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 4.070856 3.821216 7.4839502 3.8212156 4.3728077 0.9679242 0.10900833 0.093275 0.191750 0.098475 0.83695530 0.01247224 FALSE FALSE
ENST00000485854 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding_CDS_not_defined 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 1.355678 2.225306 0.3278752 0.6161922 0.1895591 -2.7259102 0.04551667 0.067675 0.008400 -0.059275 0.11122672 0.01247224   FALSE
ENST00000496867 ENSG00000157954 No_inf pgKDN_inf WIPI2 protein_coding protein_coding_CDS_not_defined 30.34583 33.95708 33.69267 2.435027 3.15372 -0.01127424 2.198865 0.000000 4.7571351 0.0000000 1.8499663 8.8969787 0.07278333 0.000000 0.146825 0.146825 0.01925524 0.01247224 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000157954 E001 0.6001170 0.0149877388 0.0879700476 0.307630517 7 5190196 5190232 37 + 0.327 0.084 -2.399
ENSG00000157954 E002 0.8357591 0.0129702930 0.0183041539 0.119532175 7 5190233 5190245 13 + 0.429 0.084 -2.984
ENSG00000157954 E003 1.5515930 0.0085101638 0.0017384356 0.022890817 7 5190246 5190258 13 + 0.612 0.154 -2.858
ENSG00000157954 E004 1.5515930 0.0085101638 0.0017384356 0.022890817 7 5190259 5190264 6 + 0.612 0.154 -2.858
ENSG00000157954 E005 1.9059383 0.0073187885 0.0001839446 0.003904316 7 5190265 5190272 8 + 0.693 0.154 -3.206
ENSG00000157954 E006 24.8404120 0.0124832294 0.0445587451 0.206339088 7 5190273 5190493 221 + 1.476 1.349 -0.441
ENSG00000157954 E007 0.0000000       7 5190693 5190843 151 +      
ENSG00000157954 E008 7.5915128 0.0030167962 0.2212004506 0.508253104 7 5193118 5193171 54 + 0.987 0.881 -0.399
ENSG00000157954 E009 0.3709916 0.0166027523 0.7993073410   7 5193172 5193345 174 + 0.108 0.154 0.601
ENSG00000157954 E010 24.2417776 0.0021486732 0.7774750671 0.914594754 7 5199576 5199658 83 + 1.396 1.396 -0.001
ENSG00000157954 E011 1.8854317 0.0074218749 0.0162480401 0.110758568 7 5213110 5213402 293 + 0.194 0.577 2.302
ENSG00000157954 E012 0.1268540 0.0122770830 0.7382104692   7 5214186 5214268 83 + 0.000 0.084 9.612
ENSG00000157954 E013 0.3706447 0.2051259874 0.8407277132   7 5214269 5214534 266 + 0.108 0.154 0.601
ENSG00000157954 E014 16.9871167 0.0038315344 0.8820364932 0.960366533 7 5214535 5214560 26 + 1.245 1.251 0.022
ENSG00000157954 E015 37.2209653 0.0007406182 0.7928016283 0.920933809 7 5214561 5214704 144 + 1.558 1.588 0.103
ENSG00000157954 E016 0.0000000       7 5216172 5216250 79 +      
ENSG00000157954 E017 17.3036191 0.0008635122 0.2637987147 0.556968759 7 5216563 5216590 28 + 1.291 1.230 -0.214
ENSG00000157954 E018 22.4838871 0.0008772040 0.0024928318 0.030044334 7 5216591 5216659 69 + 1.455 1.286 -0.587
ENSG00000157954 E019 0.0000000       7 5216749 5216863 115 +      
ENSG00000157954 E020 25.6807459 0.0255662073 0.0444308880 0.206133412 7 5217090 5217187 98 + 1.504 1.349 -0.536
ENSG00000157954 E021 0.2536433 0.0160575092 0.3710591946   7 5217188 5217921 734 + 0.000 0.154 10.554
ENSG00000157954 E022 27.0167607 0.0326652191 0.4034886958 0.686471535 7 5217922 5218014 93 + 1.476 1.414 -0.214
ENSG00000157954 E023 0.7522145 0.0259007402 0.1936676935 0.473493807 7 5218015 5219031 1017 + 0.108 0.315 1.923
ENSG00000157954 E024 24.1440456 0.0229362829 0.9870876446 0.999619881 7 5222602 5222672 71 + 1.386 1.400 0.046
ENSG00000157954 E025 0.5083889 0.0160582606 0.0904709029 0.312385255 7 5222673 5222812 140 + 0.000 0.268 11.502
ENSG00000157954 E026 34.0755417 0.0009419686 0.0319181977 0.168854936 7 5225823 5225930 108 + 1.590 1.498 -0.315
ENSG00000157954 E027 0.9874472 0.1887963312 0.8365616621 0.941413330 7 5225931 5225949 19 + 0.265 0.315 0.339
ENSG00000157954 E028 10.0051354 0.0040750125 0.0001226008 0.002806330 7 5225950 5227179 1230 + 0.762 1.159 1.491
ENSG00000157954 E029 45.8133052 0.0023829273 0.1666860596 0.437046028 7 5227180 5227344 165 + 1.691 1.644 -0.158
ENSG00000157954 E030 40.5029623 0.0003984480 0.7891154152 0.919047071 7 5228104 5228211 108 + 1.609 1.614 0.016
ENSG00000157954 E031 0.8700650 0.0412038611 0.4711069684 0.738621427 7 5229408 5229607 200 + 0.194 0.315 0.924
ENSG00000157954 E032 39.4293245 0.0003816258 0.8302984576 0.938498675 7 5229608 5229705 98 + 1.584 1.611 0.093
ENSG00000157954 E033 12.8156203 0.0011837032 0.8706923023 0.955460307 7 5229706 5229738 33 + 1.117 1.146 0.106
ENSG00000157954 E034 267.8916858 0.0046719156 0.0001170649 0.002707451 7 5230835 5233840 3006 + 2.356 2.465 0.363

Help

Please Click HERE to learn more details about the results from DEXseq.