ENSG00000158473

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368171 ENSG00000158473 No_inf pgKDN_inf CD1D protein_coding protein_coding 19.05539 36.16935 11.7009 0.7106837 0.981969 -1.627315 4.068656 9.095696 0.0000000 3.5869858 0.0000000 -9.830626 0.19314167 0.256625 0.000000 -0.256625 0.055627287 0.001727938 FALSE TRUE
ENST00000674047 ENSG00000158473 No_inf pgKDN_inf CD1D protein_coding retained_intron 19.05539 36.16935 11.7009 0.7106837 0.981969 -1.627315 4.438736 9.529185 1.3580809 0.8925824 1.1512821 -2.801712 0.20642500 0.262900 0.096775 -0.166125 0.243685182 0.001727938 FALSE TRUE
ENST00000674085 ENSG00000158473 No_inf pgKDN_inf CD1D protein_coding protein_coding 19.05539 36.16935 11.7009 0.7106837 0.981969 -1.627315 3.673038 2.771957 7.4427086 2.7719575 0.6113519 1.421664 0.27345833 0.072375 0.650175 0.577800 0.001727938 0.001727938 FALSE TRUE
MSTRG.2046.13 ENSG00000158473 No_inf pgKDN_inf CD1D protein_coding   19.05539 36.16935 11.7009 0.7106837 0.981969 -1.627315 1.424297 3.057427 0.8901179 1.1130800 0.1539305 -1.768843 0.06702500 0.086250 0.080150 -0.006100 0.997188823 0.001727938 TRUE FALSE
MSTRG.2046.14 ENSG00000158473 No_inf pgKDN_inf CD1D protein_coding   19.05539 36.16935 11.7009 0.7106837 0.981969 -1.627315 2.455233 6.162658 0.1964884 0.7267446 0.1964884 -4.901759 0.09785833 0.169900 0.013600 -0.156300 0.007509125 0.001727938 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158473 E001 0.3811266 0.0253122367 6.359612e-01   1 158173371 158173443 73 + 0.000 0.148 9.133
ENSG00000158473 E002 0.0000000       1 158178030 158178039 10 +      
ENSG00000158473 E003 1.1328702 0.0107998312 3.571347e-01 6.468311e-01 1 158178040 158178068 29 + 0.159 0.318 1.284
ENSG00000158473 E004 0.8810485 0.1589307649 6.347241e-01 8.439019e-01 1 158179947 158180162 216 + 0.159 0.258 0.869
ENSG00000158473 E005 3.2549140 0.0044649039 6.041243e-01 8.273713e-01 1 158180819 158180888 70 + 0.508 0.584 0.355
ENSG00000158473 E006 1.6143190 0.0109289072 5.515637e-01 7.954241e-01 1 158180889 158180894 6 + 0.443 0.345 -0.546
ENSG00000158473 E007 10.2633829 0.0015316844 3.872977e-01 6.732149e-01 1 158180895 158181035 141 + 0.908 0.996 0.329
ENSG00000158473 E008 5.3837276 0.0130545367 4.613426e-01 7.321143e-01 1 158181036 158181050 15 + 0.658 0.758 0.414
ENSG00000158473 E009 13.5613664 0.0011449271 3.279398e-01 6.204478e-01 1 158181051 158181162 112 + 1.156 1.067 -0.319
ENSG00000158473 E010 7.5351032 0.0130288582 1.225699e-01 3.705216e-01 1 158181229 158181454 226 + 0.698 0.897 0.787
ENSG00000158473 E011 14.6964954 0.0010264495 4.792000e-01 7.450538e-01 1 158181455 158181489 35 + 1.169 1.106 -0.227
ENSG00000158473 E012 46.6109172 0.0015893522 2.723352e-01 5.660679e-01 1 158181490 158181721 232 + 1.644 1.584 -0.202
ENSG00000158473 E013 3.6679828 0.0749912512 3.769473e-02 1.872722e-01 1 158181722 158181864 143 + 0.276 0.667 2.039
ENSG00000158473 E014 5.0537417 0.0029011864 7.571513e-03 6.657780e-02 1 158181865 158182031 167 + 0.367 0.778 1.909
ENSG00000158473 E015 38.2273970 0.0008561169 7.951446e-01 9.221637e-01 1 158182032 158182177 146 + 1.506 1.517 0.038
ENSG00000158473 E016 31.0081473 0.0004646794 1.523837e-01 4.163244e-01 1 158182178 158182310 133 + 1.494 1.406 -0.303
ENSG00000158473 E017 4.0194294 0.0035694044 2.749913e-01 5.684942e-01 1 158182311 158182375 65 + 0.508 0.667 0.717
ENSG00000158473 E018 5.4262105 0.0026997627 1.592455e-02 1.094479e-01 1 158182376 158182434 59 + 0.443 0.797 1.570
ENSG00000158473 E019 27.7309022 0.0005615654 4.475065e-07 2.238944e-05 1 158182435 158182877 443 + 1.049 1.441 1.383
ENSG00000158473 E020 59.3961412 0.0002479775 6.322584e-01 8.424178e-01 1 158182878 158183156 279 + 1.720 1.696 -0.082
ENSG00000158473 E021 3.7259130 0.0041965883 4.172966e-01 6.970318e-01 1 158183931 158183935 5 + 0.698 0.584 -0.493
ENSG00000158473 E022 42.6740553 0.0004257888 3.361476e-02 1.743919e-01 1 158183936 158184035 100 + 1.644 1.534 -0.373
ENSG00000158473 E023 176.1201652 0.0076245520 4.271431e-01 7.056555e-01 1 158184129 158186427 2299 + 2.189 2.161 -0.092

Help

Please Click HERE to learn more details about the results from DEXseq.