ENSG00000158517

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000289473 ENSG00000158517 No_inf pgKDN_inf NCF1 protein_coding protein_coding 76.37528 35.13697 91.17688 1.157788 1.372002 1.375426 65.16092 28.41144 83.3445 0.9924491 1.133898 1.552281 0.8457833 0.80845 0.91435 0.1059 0.001948613 0.001948613 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158517 E001 0.0000000       7 74774011 74774103 93 +      
ENSG00000158517 E002 0.0000000       7 74776809 74776853 45 +      
ENSG00000158517 E003 0.1268540 0.0123707725 0.209601152   7 74777267 74777268 2 + 0.000 0.138 11.774
ENSG00000158517 E004 0.2539903 0.0161583517 0.061423811   7 74777269 74777347 79 + 0.000 0.243 13.874
ENSG00000158517 E005 0.1187032 0.0119322492 1.000000000   7 74777348 74777420 73 + 0.064 0.000 -10.593
ENSG00000158517 E006 0.1187032 0.0119322492 1.000000000   7 74777554 74777701 148 + 0.064 0.000 -10.593
ENSG00000158517 E007 0.1271363 0.0124430488 0.209544864   7 74778307 74778328 22 + 0.000 0.138 12.888
ENSG00000158517 E008 0.4833718 0.5150067876 1.000000000   7 74778329 74778399 71 + 0.170 0.138 -0.354
ENSG00000158517 E009 8.6883090 0.0017777113 0.911650402 0.97179299 7 74779082 74779157 76 + 0.953 0.966 0.048
ENSG00000158517 E010 18.4971677 0.0008039312 0.444999639 0.71953057 7 74779257 74779422 166 + 1.242 1.296 0.190
ENSG00000158517 E011 0.0000000       7 74780157 74780226 70 +      
ENSG00000158517 E012 0.0000000       7 74780396 74780779 384 +      
ENSG00000158517 E013 0.0000000       7 74780780 74780835 56 +      
ENSG00000158517 E014 0.0000000       7 74781552 74781622 71 +      
ENSG00000158517 E015 28.6605385 0.0005945419 0.265605346 0.55892153 7 74782939 74783061 123 + 1.459 1.398 -0.210
ENSG00000158517 E016 3.6821353 0.0041439956 0.007843365 0.06822297 7 74783062 74783442 381 + 0.510 0.845 1.426
ENSG00000158517 E017 0.9644450 0.1169792866 0.797819880 0.92380567 7 74783443 74783524 82 + 0.292 0.243 -0.353
ENSG00000158517 E018 41.3433782 0.0092161437 0.407031184 0.68958128 7 74783525 74783632 108 + 1.609 1.564 -0.152
ENSG00000158517 E019 11.4073161 0.0013218761 0.131672009 0.38499149 7 74785182 74785261 80 + 1.102 0.966 -0.497
ENSG00000158517 E020 18.9632810 0.0134976011 0.716052313 0.88551457 7 74785262 74785299 38 + 1.261 1.287 0.093
ENSG00000158517 E021 0.0000000       7 74785300 74785546 247 +      
ENSG00000158517 E022 31.9936837 0.0070883770 0.728542413 0.89176095 7 74787984 74788088 105 + 1.480 1.502 0.075
ENSG00000158517 E023 0.8623236 0.0479339286 0.151998384 0.41569296 7 74788089 74788558 470 + 0.170 0.398 1.648
ENSG00000158517 E024 18.7129354 0.0008855721 0.773572561 0.91293106 7 74788559 74788704 146 + 1.257 1.279 0.076
ENSG00000158517 E025 0.0000000       7 74789039 74789315 277 +      

Help

Please Click HERE to learn more details about the results from DEXseq.