ENSG00000158545

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301011 ENSG00000158545 No_inf pgKDN_inf ZC3H18 protein_coding protein_coding 28.78104 32.47963 27.78795 1.05863 2.458774 -0.225001 16.6766677 15.327848 17.1609926 0.9667847 0.4845783 0.1628773 0.59322500 0.475925 0.63040 0.154475 4.292688e-01 6.891937e-09 FALSE TRUE
ENST00000452588 ENSG00000158545 No_inf pgKDN_inf ZC3H18 protein_coding protein_coding 28.78104 32.47963 27.78795 1.05863 2.458774 -0.225001 3.2401230 2.276355 4.1447090 0.8185735 0.3522256 0.8616980 0.11629167 0.069000 0.15390 0.084900 4.463905e-01 6.891937e-09 FALSE TRUE
ENST00000565583 ENSG00000158545 No_inf pgKDN_inf ZC3H18 protein_coding protein_coding 28.78104 32.47963 27.78795 1.05863 2.458774 -0.225001 1.9337397 5.801219 0.0000000 0.8605215 0.0000000 -9.1826971 0.05896667 0.176900 0.00000 -0.176900 6.891937e-09 6.891937e-09 FALSE FALSE
ENST00000566317 ENSG00000158545 No_inf pgKDN_inf ZC3H18 protein_coding retained_intron 28.78104 32.47963 27.78795 1.05863 2.458774 -0.225001 0.9492746 0.000000 2.8478237 0.0000000 1.7064625 8.1587731 0.02988333 0.000000 0.08965 0.089650 4.038832e-01 6.891937e-09 FALSE FALSE
ENST00000566496 ENSG00000158545 No_inf pgKDN_inf ZC3H18 protein_coding retained_intron 28.78104 32.47963 27.78795 1.05863 2.458774 -0.225001 3.1052049 5.028647 0.8742477 0.5045360 0.2722399 -2.5105138 0.10627500 0.154150 0.03435 -0.119800 4.492858e-02 6.891937e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158545 E001 4.8991122 0.0045073656 0.7142169413 0.884879549 16 88570403 88570477 75 + 0.789 0.752 -0.148
ENSG00000158545 E002 9.0233682 0.0016141839 0.1537290967 0.418585839 16 88570478 88570566 89 + 1.063 0.938 -0.461
ENSG00000158545 E003 20.8897724 0.0007397879 0.1067214696 0.342267690 16 88577110 88577375 266 + 1.388 1.292 -0.334
ENSG00000158545 E004 30.8450185 0.0010966571 0.1926118837 0.472496058 16 88577376 88577726 351 + 1.535 1.471 -0.217
ENSG00000158545 E005 9.4233022 0.0106054794 0.4248875220 0.703999374 16 88586600 88586616 17 + 1.053 0.982 -0.261
ENSG00000158545 E006 13.4285380 0.0010519386 0.1172113898 0.361548704 16 88586617 88586684 68 + 1.216 1.101 -0.411
ENSG00000158545 E007 5.6967075 0.0026682566 0.0222290648 0.135576431 16 88587542 88587613 72 + 0.941 0.695 -0.968
ENSG00000158545 E008 22.5093538 0.0073885174 0.0066525895 0.060840748 16 88598178 88598326 149 + 1.460 1.277 -0.636
ENSG00000158545 E009 12.8521182 0.0011515200 0.4854222897 0.749242073 16 88598620 88598712 93 + 1.166 1.117 -0.176
ENSG00000158545 E010 9.9124298 0.0031954411 0.5312233180 0.781912737 16 88599791 88599835 45 + 1.063 1.013 -0.184
ENSG00000158545 E011 18.8983232 0.0012053678 0.0248272881 0.144870453 16 88599836 88599948 113 + 1.370 1.226 -0.504
ENSG00000158545 E012 0.2533610 0.0160062231 0.2850320297   16 88608517 88608933 417 + 0.000 0.166 9.064
ENSG00000158545 E013 22.0021318 0.0011836625 0.0945582306 0.319983913 16 88608934 88609051 118 + 1.411 1.312 -0.341
ENSG00000158545 E014 0.0000000       16 88609052 88609264 213 +      
ENSG00000158545 E015 37.0057663 0.0026508357 0.3898157022 0.675349975 16 88611268 88611536 269 + 1.598 1.560 -0.129
ENSG00000158545 E016 29.2383373 0.0020020458 0.1869507216 0.464860988 16 88622197 88622388 192 + 1.514 1.447 -0.233
ENSG00000158545 E017 0.2447669 0.0163354401 0.9272523530   16 88622389 88623218 830 + 0.100 0.091 -0.148
ENSG00000158545 E018 21.1627893 0.0010369584 0.1927630423 0.472567360 16 88623219 88623344 126 + 1.384 1.307 -0.265
ENSG00000158545 E019 0.0000000       16 88623542 88623957 416 +      
ENSG00000158545 E020 16.0326792 0.0050511480 0.3769105416 0.664062889 16 88623958 88624042 85 + 1.262 1.201 -0.214
ENSG00000158545 E021 9.8111928 0.0189569662 0.9677684323 0.993494933 16 88624043 88624062 20 + 1.033 1.032 -0.004
ENSG00000158545 E022 2.3612455 0.0397103550 0.2025069584 0.484927141 16 88624063 88624601 539 + 0.406 0.604 0.967
ENSG00000158545 E023 18.2093115 0.0019070581 0.1524848346 0.416474253 16 88624602 88624687 86 + 1.330 1.237 -0.323
ENSG00000158545 E024 13.5750805 0.0019749544 0.2807426313 0.573931715 16 88624688 88624745 58 + 1.203 1.125 -0.278
ENSG00000158545 E025 14.4768743 0.0011604811 0.9317566103 0.980094415 16 88625202 88625248 47 + 1.188 1.188 -0.001
ENSG00000158545 E026 11.5649297 0.0106501059 0.5451053063 0.791144199 16 88625249 88625267 19 + 1.063 1.125 0.222
ENSG00000158545 E027 9.9692888 0.0016765364 0.0001511583 0.003322157 16 88625268 88626699 1432 + 0.807 1.168 1.342
ENSG00000158545 E028 5.9066219 0.0675078510 0.0004813262 0.008475301 16 88627062 88627621 560 + 0.448 1.013 2.367
ENSG00000158545 E029 29.2758530 0.0105645411 0.4143189790 0.694619315 16 88627622 88627782 161 + 1.444 1.507 0.217
ENSG00000158545 E030 10.6107551 0.0013053724 0.1624046041 0.430826320 16 88627920 88627921 2 + 0.989 1.117 0.465
ENSG00000158545 E031 32.8624253 0.0217811110 0.2214420087 0.508594994 16 88627922 88628119 198 + 1.475 1.569 0.322
ENSG00000158545 E032 0.7437762 0.0254330046 0.5029697060 0.762574385 16 88628648 88628757 110 + 0.181 0.286 0.852
ENSG00000158545 E033 21.2918198 0.0196849483 0.4167664365 0.696621346 16 88628758 88628854 97 + 1.302 1.381 0.272
ENSG00000158545 E034 1.2525787 0.0109565190 0.0777383923 0.285325049 16 88630155 88630484 330 + 0.181 0.456 1.852
ENSG00000158545 E035 23.2972703 0.0022599200 0.7140936292 0.884874248 16 88630485 88630581 97 + 1.393 1.376 -0.057
ENSG00000158545 E036 50.7615277 0.0004272202 0.4586170902 0.730456875 16 88631101 88631339 239 + 1.692 1.729 0.125
ENSG00000158545 E037 37.5618133 0.0051864255 0.1420065122 0.400931524 16 88631340 88631493 154 + 1.535 1.622 0.300
ENSG00000158545 E038 41.4121677 0.0003371242 0.0002425984 0.004906000 16 88631494 88631671 178 + 1.521 1.697 0.600
ENSG00000158545 E039 29.6280889 0.0157162213 0.0664085423 0.259560716 16 88631672 88631964 293 + 1.402 1.543 0.487

Help

Please Click HERE to learn more details about the results from DEXseq.