ENSG00000158636

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000334736 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.1585086 0.0000000 0.4755258 0.00000000 0.4755258 5.6014760 0.02683333 0.000000 0.080500 0.080500 0.8437553992 0.0005302914 FALSE TRUE
ENST00000524767 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.3080632 0.0000000 0.9241895 0.00000000 0.9241895 6.5456433 0.04625000 0.000000 0.138750 0.138750 0.8466549518 0.0005302914 FALSE TRUE
ENST00000525038 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.1903459 0.0000000 0.5710377 0.00000000 0.5710377 5.8605598 0.02387500 0.000000 0.071625 0.071625 0.8370945062 0.0005302914 FALSE TRUE
ENST00000525919 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 1.0211148 0.6321268 1.0943513 0.63212683 0.6536990 0.7822689 0.18295000 0.094850 0.170400 0.075550 0.8239680878 0.0005302914 FALSE TRUE
ENST00000531641 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding retained_intron 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.6236664 1.0767970 0.3260750 0.26985136 0.1892748 -1.6932272 0.09566667 0.152475 0.047525 -0.104950 0.4932219634 0.0005302914 FALSE TRUE
ENST00000531793 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.6994960 1.6199691 0.0000000 0.21331475 0.0000000 -7.3487008 0.11190833 0.238275 0.000000 -0.238275 0.0005302914 0.0005302914 FALSE TRUE
ENST00000532719 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.3256405 0.0000000 0.7933294 0.00000000 0.4828970 6.3279198 0.04588333 0.000000 0.106975 0.106975 0.4676538342 0.0005302914 FALSE TRUE
ENST00000533988 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.5299689 0.4478160 0.5234794 0.15943235 0.1910577 0.2206646 0.08068333 0.059800 0.073125 0.013325 0.9788556217 0.0005302914   FALSE
ENST00000534573 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding retained_intron 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.6626371 0.8618122 1.0089848 0.20483988 0.6044287 0.2250432 0.10060833 0.122975 0.157025 0.034050 0.9118714492 0.0005302914 FALSE FALSE
ENST00000695367 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding protein_coding 6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.7282499 1.1814247 0.0000000 0.69646269 0.0000000 -6.8965440 0.11574167 0.149550 0.000000 -0.149550 0.4720738875 0.0005302914 FALSE TRUE
MSTRG.5231.1 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding   6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.3731183 0.1836077 0.7169594 0.06194736 0.4716138 1.9087382 0.05402500 0.028375 0.095375 0.067000 0.8893779040 0.0005302914 FALSE TRUE
MSTRG.5231.10 ENSG00000158636 No_inf pgKDN_inf EMSY protein_coding   6.319737 6.896873 6.842353 0.6510752 0.4264089 -0.01143305 0.3016562 0.5874629 0.0000000 0.58746288 0.0000000 -5.9007772 0.05534167 0.113000 0.000000 -0.113000 0.8642127589 0.0005302914 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000158636 E001 0.0000000       11 76444923 76445017 95 +      
ENSG00000158636 E002 0.0000000       11 76445018 76445021 4 +      
ENSG00000158636 E003 0.0000000       11 76445022 76445024 3 +      
ENSG00000158636 E004 0.1176306 0.0118004231 0.574919673   11 76445025 76445041 17 + 0.093 0.000 -9.840
ENSG00000158636 E005 0.1176306 0.0118004231 0.574919673   11 76445042 76445043 2 + 0.093 0.000 -12.228
ENSG00000158636 E006 0.1176306 0.0118004231 0.574919673   11 76445044 76445046 3 + 0.093 0.000 -12.228
ENSG00000158636 E007 0.1176306 0.0118004231 0.574919673   11 76445047 76445051 5 + 0.093 0.000 -12.228
ENSG00000158636 E008 0.9965106 0.0116940726 0.126871231 0.37756505 11 76445052 76445128 77 + 0.169 0.399 1.659
ENSG00000158636 E009 1.1030380 0.2650510472 0.569064770 0.80616526 11 76446900 76446938 39 + 0.291 0.353 0.399
ENSG00000158636 E010 1.9392055 0.0693010868 0.449878988 0.72340638 11 76446939 76447008 70 + 0.530 0.399 -0.662
ENSG00000158636 E011 3.0308389 0.0047576690 0.216683283 0.50282713 11 76451858 76451957 100 + 0.683 0.513 -0.756
ENSG00000158636 E012 1.9492115 0.1345351988 0.781188517 0.91579908 11 76453314 76453388 75 + 0.498 0.440 -0.289
ENSG00000158636 E013 1.2229032 0.0107476447 0.916198925 0.97370534 11 76453389 76453931 543 + 0.341 0.353 0.074
ENSG00000158636 E014 0.8512823 0.0469743483 0.784155566 0.91683423 11 76454749 76454790 42 + 0.291 0.244 -0.341
ENSG00000158636 E015 0.0000000       11 76458161 76458182 22 +      
ENSG00000158636 E016 2.4017694 0.0062416222 0.033691418 0.17465750 11 76458183 76458358 176 + 0.661 0.353 -1.511
ENSG00000158636 E017 0.4879983 0.0762778358 0.946707824   11 76458359 76459932 1574 + 0.169 0.177 0.075
ENSG00000158636 E018 0.3532727 0.0164576587 0.116301089   11 76459933 76459935 3 + 0.234 0.000 -13.595
ENSG00000158636 E019 1.7868543 0.0077672249 0.004257006 0.04435106 11 76459936 76460085 150 + 0.613 0.177 -2.626
ENSG00000158636 E020 0.3533378 0.0157664631 0.116486561   11 76460086 76461015 930 + 0.234 0.000 -13.596
ENSG00000158636 E021 3.7336191 0.0040116361 0.029405892 0.16114719 11 76463821 76464080 260 + 0.796 0.513 -1.215
ENSG00000158636 E022 4.6409865 0.0438120688 0.877541470 0.95843514 11 76472564 76472840 277 + 0.761 0.742 -0.078
ENSG00000158636 E023 4.9916947 0.0140060969 0.403495656 0.68647153 11 76496215 76496469 255 + 0.828 0.722 -0.423
ENSG00000158636 E024 0.2447669 0.0162554701 0.958688004   11 76496470 76497231 762 + 0.093 0.097 0.074
ENSG00000158636 E025 1.2330929 0.0230285774 0.469922612 0.73790451 11 76513386 76513396 11 + 0.291 0.399 0.659
ENSG00000158636 E026 3.0730446 0.0051533513 0.445837213 0.72021398 11 76513397 76513535 139 + 0.559 0.655 0.422
ENSG00000158636 E027 3.9207376 0.0037940851 0.848346981 0.94630403 11 76516142 76516312 171 + 0.683 0.701 0.074
ENSG00000158636 E028 0.2533610 0.0160492279 0.220242033   11 76516313 76516842 530 + 0.000 0.177 12.286
ENSG00000158636 E029 1.8441692 0.1948652598 0.773604838 0.91293159 11 76523155 76523175 21 + 0.427 0.479 0.267
ENSG00000158636 E030 4.1461231 0.1460775716 0.621885801 0.83699549 11 76523176 76523291 116 + 0.762 0.655 -0.441
ENSG00000158636 E031 2.6823211 0.0265385204 0.508905334 0.76700113 11 76526462 76526478 17 + 0.613 0.513 -0.457
ENSG00000158636 E032 5.7000689 0.0025624214 0.092319275 0.31558377 11 76526479 76526635 157 + 0.912 0.722 -0.745
ENSG00000158636 E033 6.1500976 0.0023740105 0.276256197 0.56977443 11 76528268 76528466 199 + 0.796 0.905 0.422
ENSG00000158636 E034 5.8493124 0.0025772110 0.524812723 0.77780906 11 76535895 76536059 165 + 0.872 0.798 -0.288
ENSG00000158636 E035 5.5221875 0.0101650597 0.524627298 0.77768384 11 76537795 76537950 156 + 0.779 0.847 0.267
ENSG00000158636 E036 2.3000959 0.0662968730 0.190947470 0.47029687 11 76539599 76539640 42 + 0.613 0.399 -1.042
ENSG00000158636 E037 1.1069396 0.0128314039 0.666535224 0.86133908 11 76542010 76542050 41 + 0.291 0.353 0.396
ENSG00000158636 E038 1.4778635 0.0086534290 0.491533416 0.75379918 11 76542051 76542145 95 + 0.341 0.441 0.560
ENSG00000158636 E039 1.1150200 0.0113228783 0.272380492 0.56606790 11 76542146 76542167 22 + 0.234 0.399 1.074
ENSG00000158636 E040 0.7361595 0.0146092838 0.936263629 0.98182891 11 76542168 76542215 48 + 0.234 0.244 0.074
ENSG00000158636 E041 1.8190227 0.0694489878 0.299030663 0.59189371 11 76542216 76542238 23 + 0.530 0.353 -0.927
ENSG00000158636 E042 3.7708697 0.0057568584 0.287158221 0.58051619 11 76542239 76542367 129 + 0.743 0.604 -0.589
ENSG00000158636 E043 11.0760741 0.0031485976 0.210434688 0.49488029 11 76544259 76544746 488 + 1.135 1.023 -0.406
ENSG00000158636 E044 4.6417897 0.0031598103 0.905669371 0.96986681 11 76544747 76544822 76 + 0.761 0.742 -0.078
ENSG00000158636 E045 1.5046484 0.0090295101 0.012317086 0.09192390 11 76544823 76544999 177 + 0.169 0.545 2.396
ENSG00000158636 E046 5.5144390 0.0024869781 0.708145631 0.88166800 11 76545797 76545947 151 + 0.796 0.831 0.138
ENSG00000158636 E047 10.2196137 0.0015575081 0.079077785 0.28836925 11 76545948 76546297 350 + 0.971 1.116 0.530
ENSG00000158636 E048 0.0000000       11 76547028 76547100 73 +      
ENSG00000158636 E049 66.0388379 0.0002913304 0.007611813 0.06677985 11 76549952 76553031 3080 + 1.788 1.861 0.246

Help

Please Click HERE to learn more details about the results from DEXseq.